Aliases for IFITM10 Gene
Aliases for IFITM10 Gene
External Ids for IFITM10 Gene
- HGNC: 40022
- Entrez Gene: 402778
- Ensembl: ENSG00000244242
- UniProtKB: A6NMD0
Previous GeneCards Identifiers for IFITM10 Gene
- GC11M001755
Summaries for IFITM10 Gene
GeneCards Summary for IFITM10 Gene
IFITM10 (Interferon Induced Transmembrane Protein 10) is a Protein Coding gene. An important paralog of this gene is IFITM2.
Additional gene information for IFITM10 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IFITM10 Gene
Genomics for IFITM10 Gene
GeneHancer (GH) Regulatory Elements for IFITM10 Gene
Promoters and enhancers for IFITM10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around IFITM10 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for IFITM10 Gene
Genomic Locations for IFITM10 Gene
- chr11:1,732,410-1,750,594
- (GRCh38/hg38)
- Size:
- 18,185 bases
- Orientation:
- Minus strand
- chr11:1,753,640-1,771,824
- (GRCh37/hg19)
Genomic View for IFITM10 Gene
Genes around IFITM10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.5 by Ensembl
- 11p15.5 by Entrez Gene
- 11p15.5 by HGNC
IFITM10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IFITM10 Gene
Proteins for IFITM10 Gene
-
Protein details for IFITM10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NMD0-IFM10_HUMAN
- Recommended name:
- Interferon-induced transmembrane protein 10
- Protein Accession:
- A6NMD0
- A6NEU7
Protein attributes for IFITM10 Gene
- Size:
- 228 amino acids
- Molecular mass:
- 24599 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAF82263.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Post-translational modifications for IFITM10 Gene
No Post-translational modifications
Other Protein References for IFITM10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for IFITM10
Protein Products
-
OriGene Purified Proteins for IFITM10
- Search Origene for MassSpec and Protein Over-expression Lysates for IFITM10
- Origene Custom Protein Services for IFITM10
- Search GeneTex for Proteins for IFITM10
Assay Products
No data available for DME Specific Peptides for IFITM10 Gene
Domains & Families for IFITM10 Gene
Gene Families for IFITM10 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for IFITM10 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for IFITM10 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
A6NMD0- Family:
-
- Belongs to the CD225/Dispanin family.
Function for IFITM10 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IFITM10
-
-
ViGene Biosciences lentiviral particle packaged cDNA for IFITM10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFITM10 gene
- Search ViGene Biosciences for IFITM10
CRISPR Products
-
OriGene CRISPR knockouts for IFITM10
- genomics-online: gRNA clones - Search results for available IFITM10 gene related products
- Applied Biological Materials CRISPR for IFITM10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for IFITM10
- GenScript: Design CRISPR guide RNA sequences for IFITM10
miRNA Products
- Search ViGene Biosciences for IFITM10
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available IFITM10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for IFITM10 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for IFITM10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFITM10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available IFITM10 gene related products
- orf clones - Search results for available IFITM10 gene related products
- Applied Biological Materials Clones for IFITM10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for IFITM10
-
ViGene Biosciences adenoviral particle packaged cDNA for IFITM10 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IFITM10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFITM10 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IFITM10 Gene
Localization for IFITM10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for IFITM10 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| peroxisome | 2 |
| mitochondrion | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IFITM10 Gene
Pathways & Interactions for IFITM10 Gene
No Data Available
Interacting Proteins for IFITM10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0009607 | response to biotic stimulus | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for IFITM10 Gene
Transcripts for IFITM10 Gene
mRNA/cDNA for IFITM10 Gene
- (1) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for IFITM10 Gene
- Interferon induced transmembrane protein 10:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for IFITM10
- genomics-online: gRNA clones - Search results for available IFITM10 gene related products
- Applied Biological Materials CRISPR for IFITM10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for IFITM10
- GenScript: Design CRISPR guide RNA sequences for IFITM10
miRNA Products
- Search ViGene Biosciences for IFITM10
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for available IFITM10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for IFITM10 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for IFITM10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFITM10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available IFITM10 gene related products
- orf clones - Search results for available IFITM10 gene related products
- Applied Biological Materials Clones for IFITM10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for IFITM10 Gene
mRNA differential expression in normal tissues according to GTEx for IFITM10 Gene
This gene is overexpressed in Adrenal Gland (x6.9) and Artery - Aorta (x4.2).
NURSA nuclear receptor signaling pathways regulating expression of IFITM10 Gene:
IFITM10SOURCE GeneReport for Unigene cluster for IFITM10 Gene:
Hs.121575Evidence on tissue expression from TISSUES for IFITM10 Gene
- Nervous system(4.2)
Primer Products
- genomics-online: primer clones - Search results for available IFITM10 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IFITM10 Gene
Orthologs for IFITM10 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| LOC613464 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | IFITM10 33 |
|
||
| -- 34 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Ifitm10 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Ifitm10 34 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | IFITM10 33 |
|
||
| -- 34 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ifitm10 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | si:dkey-226m8.7 34 |
|
ManyToMany |
- Species where no ortholog for IFITM10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for IFITM10 Gene
Variants for IFITM10 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000306608 | -- | 1,733,667(-) | TCTTCTTCT/TCTTCT | 3_prime_UTR_variant | |
| rs1000588534 | -- | 1,738,799(-) | G/T | intron_variant | |
| rs1000676064 | -- | 1,744,933(-) | T/G | intron_variant | |
| rs1000734176 | -- | 1,749,904(-) | C/G | intron_variant | |
| rs1000884542 | -- | 1,751,610(-) | G/A | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2403037 | CNV | deletion | 18987734 |
| esv3370062 | CNV | duplication | 20981092 |
| nsv1121470 | CNV | deletion | 24896259 |
| nsv1129154 | CNV | insertion | 24896259 |
| nsv1137983 | CNV | deletion | 24896259 |
| nsv1140466 | CNV | tandem duplication | 24896259 |
| nsv467645 | CNV | gain | 19166990 |
| nsv553047 | CNV | gain | 21841781 |
| nsv7642 | CNV | insertion | 18451855 |
| nsv832049 | CNV | loss | 17160897 |
Gene Damage Index Score:
2.08;
37.99% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for IFITM10 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- IFITM10
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IFITM10 Gene
Disorders for IFITM10 Gene
Additional Disease Information for IFITM10
No disorders were found for IFITM10 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IFITM10 Gene
Publications for IFITM10 Gene
- The dispanins: a novel gene family of ancient origin that contains 14 human members. (PMID: 22363774) Sällman Almén M … Schiöth HB (PloS one 2012) 3 4 58
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
Products for IFITM10 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for IFITM10
- Search Origene for MassSpec and Protein Over-expression Lysates for IFITM10
- Origene Custom Protein Services for IFITM10
- Browse OriGene Inhibitory RNA Products For IFITM10
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for IFITM10
- OriGene ORF clones in human for IFITM10
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IFITM10
- GenScript: Next-day shipping of latest version cDNA ORF clones for IFITM10 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for IFITM10
- GenScript Custom Assay Services for IFITM10
- GenScript Custom overexpressing Cell Line Services for IFITM10
- GenScript: Design CRISPR guide RNA sequences for IFITM10
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IFITM10
- Browse Sino Biological cDNA Clones
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- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
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- Browse Knockouts at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for IFITM10
- VectorBuilder custom plasmid, inducible vectors for IFITM10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFITM10
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for IFITM10
- Search GeneTex for Proteins for IFITM10
- ViGene Biosciences adenoviral particle packaged cDNA for IFITM10 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IFITM10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IFITM10 gene
- Search ViGene Biosciences for IFITM10
- Horizon Cell Lines for IFITM10
- genomics-online: cdna clones - Search results for available IFITM10 gene related products
- orf clones - Search results for available IFITM10 gene related products
- genomics-online: gRNA clones - Search results for available IFITM10 gene related products
- genomics-online: primer clones - Search results for available IFITM10 gene related products
- genomics-online: shRNA clones - Search results for available IFITM10 gene related products
Sources for IFITM10 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew