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IFI44L (Interferon Induced Protein 44 Like) is a Protein Coding gene. Diseases associated with IFI44L include Lymph Node Tuberculosis and Immunodeficiency 38 With Basal Ganglia Calcification. An important paralog of this gene is IFI44.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0005525 | GTP binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005575 | cellular_component | ND | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006955 | immune response | IBA | 21873635 |
GO:0051607 | defense response to virus | IEA,IDA | 21478870 |
ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | · | 2f | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP9: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP11: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP12: |
ExUns: | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c |
---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||
SP2: | |||||||||
SP3: | |||||||||
SP4: | |||||||||
SP5: | |||||||||
SP6: | |||||||||
SP7: | - | ||||||||
SP8: | |||||||||
SP9: | |||||||||
SP10: | |||||||||
SP11: | |||||||||
SP12: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | IFI44L 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | IFI44L 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | IFI44L 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ifi44l 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Ifi44l 30 17 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Zebrafish (Danio rerio) |
Actinopterygii | CR855320.1 31 |
|
ManyToMany | |
zgc:153654 31 |
|
ManyToMany | |||
si:ch211-197g15.8 31 |
|
ManyToMany | |||
si:ch211-197g15.9 31 |
|
ManyToMany | |||
si:dkey-193b15.5 31 |
|
ManyToMany | |||
si:ch211-197g15.7 31 |
|
ManyToMany | |||
si:ch211-197g15.6 31 31 |
|
ManyToMany | |||
si:ch211-197g15.10 31 |
|
ManyToMany | |||
si:dkey-79f11.7 31 |
|
ManyToMany | |||
si:dkeyp-9d4.2 31 |
|
ManyToMany | |||
si:dkey-79f11.9 31 |
|
ManyToMany | |||
si:dkey-79f11.5 31 |
|
ManyToMany | |||
si:ch211-208g24.8 31 |
|
ManyToMany | |||
si:dkey-79f11.4 31 |
|
ManyToMany | |||
CABZ01073795.1 31 |
|
ManyToMany | |||
si:dkey-79f11.8 31 |
|
ManyToMany | |||
CABZ01045230.1 31 |
|
ManyToMany | |||
si:dkey-79f11.10 31 |
|
ManyToMany | |||
si:dkeyp-75b4.9 31 |
|
ManyToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs143077503 | Likely Benign: not provided | 78,628,091(+) |
A/G NM_006820.4(IFI44L):c.176A>G (p.Asn59Ser) |
MISSENSE_VARIANT,INTRON | |
rs273258 | Benign: not provided. - | 78,628,357(+) |
C/Tp.Arg148Cys NM_006820.4(IFI44L):c.442C>T (p.Arg148Cys) |
MISSENSE_VARIANT,INTRON | |
rs34615115 | Benign: not provided | 78,641,602(+) |
G/A NM_006820.4(IFI44L):c.1317G>A (p.Glu439=) |
SYNONYMOUS | |
rs61729831 | Benign: not provided | 78,637,042(+) |
G/A NM_006820.4(IFI44L):c.887G>A (p.Arg296His) |
MISSENSE | |
rs761700063 | Likely Benign: not provided | 78,629,710(+) |
A/G NM_006820.4(IFI44L):c.528-10A>G |
INTRON |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2661424 | CNV | deletion | 23128226 |
esv2750218 | CNV | deletion | 23290073 |
esv3303563 | CNV | mobile element insertion | 20981092 |
esv3309841 | CNV | mobile element insertion | 20981092 |
esv3386975 | CNV | insertion | 20981092 |
esv3406252 | CNV | insertion | 20981092 |
esv3431836 | CNV | insertion | 20981092 |
esv3586552 | CNV | loss | 21293372 |
nsv1001291 | CNV | loss | 25217958 |
nsv830315 | CNV | gain | 17160897 |
Disorder | Aliases | PubMed IDs |
---|---|---|
lymph node tuberculosis |
|
|
immunodeficiency 38 with basal ganglia calcification |
|
|
potocki-shaffer syndrome |
|
|
aicardi-goutieres syndrome |
|
|