Aliases for IER2 Gene
Previous GeneCards Identifiers for IER2 Gene
GeneCards Summary for IER2 Gene
IER2 (Immediate Early Response 2) is a Protein Coding gene. Diseases associated with IER2 include Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly. An important paralog of this gene is IER5.
UniProtKB/Swiss-Prot Summary for IER2 Gene
DNA-binding protein that seems to act as a transcription factor (PubMed:19584537). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713).