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IER2 (Immediate Early Response 2) is a Protein Coding gene. Diseases associated with IER2 include Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly. An important paralog of this gene is IER5.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | 19584537 |
GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | 19584537 |
GO:0003677 | DNA binding | IEA,IDA | 19584537 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA,IDA | 22120713 |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005737 | cytoplasm | IEA,IDA | 22120713 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0030182 | neuron differentiation | ISS | -- |
GO:0045944 | positive regulation of transcription by RNA polymerase II | IDA | 19584537 |
GO:0048870 | cell motility | IMP | 22120713 |
GO:0071774 | response to fibroblast growth factor | ISS | -- |
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c |
---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||
SP2: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | IER2 30 |
|
||
Dog (Canis familiaris) |
Mammalia | IER2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | IER2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ier2 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Ier2 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | IER2 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | IER2 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | IER2 31 |
|
OneToOne |
Disorder | Aliases | PubMed IDs |
---|---|---|
short-rib thoracic dysplasia 4 with or without polydactyly |
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