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This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, a... See more...
Aliases for IAPP Gene
Aliases for IAPP Gene
External Ids for IAPP Gene
- HGNC: 5329
- Entrez Gene: 3375
- Ensembl: ENSG00000121351
- OMIM: 147940
- UniProtKB: P10997
Previous GeneCards Identifiers for IAPP Gene
- GC12P021811
- GC12P021527
- GC12P021426
- GC12P021417
- GC12P021299
- GC12P021507
Summaries for IAPP Gene
-
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]
GeneCards Summary for IAPP Gene
IAPP (Islet Amyloid Polypeptide) is a Protein Coding gene. Diseases associated with IAPP include Insulinoma and Hyperglycemia. Among its related pathways are Signaling by GPCR and Regulation of beta-cell development. Gene Ontology (GO) annotations related to this gene include identical protein binding and hormone activity. An important paralog of this gene is CALCB.
UniProtKB/Swiss-Prot Summary for IAPP Gene
-
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Additional gene information for IAPP Gene
- HGNC(5329)
- Entrez Gene(3375)
- Ensembl(ENSG00000121351)
- OMIM(147940)
- UniProtKB(P10997)
- Open Targets Platform(ENSG00000121351)
- Search for IAPP at DataMed
- Search for IAPP at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for IAPP Gene
Genomics for IAPP Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for IAPP Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH12J021372 | Promoter | 0.3 | EPDnew | 600.4 | +17.9 | 17924 | 0.1 | IAPP piR-40110-127 piR-46002-111 SLCO1A2 lnc-SLCO1A2-1 | ||
| GH12J021300 | Enhancer | 0.4 | Ensembl | 10.4 | -54.2 | -54158 | 0.8 | CEBPB ATF3 CEBPG MAFK | IAPP piR-39858-114 SLCO1A2 lnc-SLCO1A2-1 SLCO1B1 | |
| GH12J021296 | Enhancer | 0.4 | dbSUPER | 10.4 | -57.1 | -57106 | 3.3 | CTCF RAD21 SMC3 ZNF366 | IAPP piR-39858-114 SLCO1A2 lnc-SLCO1A2-1 SLCO1B1 | |
| GH12J021323 | Promoter/Enhancer | 1 | EPDnew Ensembl ENCODE dbSUPER | 0.3 | -30.3 | -30335 | 2 | NANOG POU5F1 | SLCO1A2 IAPP piR-39858-114 lnc-SLCO1A2-1 SLCO1B1 | |
| GH12J021393 | Promoter | 0.8 | Ensembl | 0.3 | +39.7 | 39742 | 1.8 | IKZF1 HDAC1 SOX6 POLR2A CTBP1 TAF9B ZSCAN29 NFRKB EP400 NCOR1 | piR-33432-103 piR-46002-111 piR-57176-114 lnc-SLCO1A2-1 SLCO1A2 piR-40110-127 IAPP |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around IAPP on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for IAPP
- Top Transcription factor binding sites by QIAGEN in the IAPP gene promoter:
-
- AP-1
- ATF-2
- c-Jun
- Cdc5
- GR
- GR-alpha
- GR-beta
- Pbx1a
- TBP
Genomic Locations for IAPP Gene
Genomic Locations for IAPP Gene
- chr12:21,354,959-21,379,980
- (GRCh38/hg38)
- Size:
- 25,022 bases
- Orientation:
- Plus strand
- chr12:21,507,893-21,532,914
- (GRCh37/hg19)
- Size:
- 25,022 bases
- Orientation:
- Plus strand
Genomic View for IAPP Gene
Genes around IAPP on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p12.1 by HGNC
- 12p12.1 by Entrez Gene
- 12p12.1 by Ensembl
IAPP Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IAPP Gene
Proteins for IAPP Gene
-
Protein details for IAPP Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P10997-IAPP_HUMAN
- Recommended name:
- Islet amyloid polypeptide
- Protein Accession:
- P10997
- Q0ZD87
- Q14598
Protein attributes for IAPP Gene
- Size:
- 89 amino acids
- Molecular mass:
- 9806 Da
- Quaternary structure:
-
- Interacts with IDE and INS. Can form homodimers. Interaction with INS inhibits homodimerization and fibril formation.
- Miscellaneous:
-
- IAPP is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.
Protein Expression for IAPP Gene
Post-translational modifications for IAPP Gene
- Amyloid fibrils are degraded by IDE.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for IAPP Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences IAPP / Amylin Monoclonal Antibody and IAPP / Amylin Antibody
- G Biosciences Immunotag™ Amylin Antibody
-
Custom Antibody ServicesOriGene Antibodies for IAPP
- Novus Biologicals Antibodies for IAPP
-
Abcam antibodies for IAPP
- Invitrogen Antibodies for IAPP (AFLGC-IAPP)
- antibodies-online: Show 48 available IAPP Antibodies ranked by validation data
- Compare Top IAPP Antibodies
-
Recommended
- 63 WB Antibodies (anti-human)
- 18 IHC Antibodies (anti-human)
- 17 IHC (p) Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 15 WB Antibodies (anti-mouse)
- 4 IHC Antibodies (anti-mouse)
- 16 WB Antibodies (anti-rat)
- 5 IHC Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for IAPP
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for IAPP
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-
Abcam proteins for IAPP
Assay Products
- RayBiotech Human Amylin EIA
- Novus Biologicals ELISA Kits for IAPP
- antibodies-online: Show 87 available IAPP Elisa Kits ranked by validation data
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-
Quality Products:
- ABIN367162
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- ABIN1380920
- ABIN367878
- ABIN1873385
- ABIN1570441
- ABIN1884498
- ABIN5696493
- ABIN628030
- ABIN5593118
- ABIN772810
- ABIN4881297
- ABIN4881384
- ABIN431403
- ABIN1570442
- ABIN1884499
- ABIN5522354
- ABIN771488
- ABIN5593119
- ABIN627217
- ABIN4881342
- ABIN776216
- ABIN628728
-
Boster Bio ELISA Kits for IAPP
-
Signalway ELISA kits for IAPP
No data available for DME Specific Peptides for IAPP Gene
Domains & Families for IAPP Gene
Gene Families for IAPP Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for IAPP Gene
- InterPro:
- Blocks:
-
- Islet amyloid protein (amylin) signature
- ProtoNet:
Suggested Antigen Peptide Sequences for IAPP Gene
- GenScript: Design optimal peptide antigens:
-
- Insulinoma amyloid peptide (IAPP_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P10997UniProtKB/Swiss-Prot:
IAPP_HUMAN :- The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
- Belongs to the calcitonin family.
- Domain:
-
- The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
- Family:
-
- Belongs to the calcitonin family.
Function for IAPP Gene
Molecular function for IAPP Gene
- UniProtKB/Swiss-Prot Function:
- Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
- GENATLAS Biochemistry:
- islet amyloid polypeptide
Phenotypes From GWAS Catalog for IAPP Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001540 | amyloid-beta binding | TAS | 22500019 |
| GO:0005102 | signaling receptor binding | TAS | 2608057 |
| GO:0005179 | hormone activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 17051221 |
| GO:0042802 | identical protein binding | IPI | 17640888 |
Phenotypes for IAPP Gene
- MGI mutant phenotypes for IAPP:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for IAPP:
Animal Models for IAPP Gene
- MGI Knock Outs for IAPP:
-
- Iapp Iapp<tm1Sgm>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for IAPP - Select products 50% OFF >
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-
Santa Cruz Biotechnology (SCBT) CRISPR for IAPP
miRNA for IAPP Gene
- miRTarBase miRNAs that target IAPP
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IAPP
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Clone Products
- Applied Biological Materials (abm): Clones for IAPP - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for IAPP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IAPP
Cell Line Products
-
Horizon Cell Lines for IAPP
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IAPP Gene
Localization for IAPP Gene
Subcellular locations from UniProtKB/Swiss-Prot for IAPP Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 3 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| endosome | 2 |
| cytosol | 2 |
| lysosome | 2 |
| golgi apparatus | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,TAS | -- |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005623 | cell | IEA | -- |
| GO:0043025 | neuronal cell body | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IAPP Gene
Pathways & Interactions for IAPP Gene
Pathways by source for IAPP Gene
12 Reactome pathways for IAPP Gene
2 KEGG pathways for IAPP Gene
Interacting Proteins for IAPP Gene
Selected Interacting proteins:
P10997-IAPP_HUMAN
ENSP00000240652
for IAPP Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for IAPP
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006915 | apoptotic process | TAS | 8152488 |
| GO:0007165 | signal transduction | IEA,TAS | 10342886 |
| GO:0007186 | G protein-coupled receptor signaling pathway | TAS | -- |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | ISS | -- |
| GO:0007204 | positive regulation of cytosolic calcium ion concentration | NAS | 22500019 |
No data available for SIGNOR curated interactions for IAPP Gene
Drugs & Compounds for IAPP Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Copper | Approved, Investigational | Pharma | Target | 249 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for IAPP Gene
mRNA/cDNA for IAPP Gene
- 2 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000240652 1942 nts (view in UCSC)
- ENST00000535428 460 nts (view in UCSC)
- ENST00000537593 351 nts (view in UCSC)
- ENST00000539393 409 nts (view in UCSC)
- ENST00000542023 2015 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for IAPP - Select products 50% OFF >
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-
Santa Cruz Biotechnology (SCBT) CRISPR for IAPP
miRNA Products
Inhibitory RNA Products
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Clone Products
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- Sino Biological Human cDNA Clone for IAPP
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| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||
| SP2: | - | ||||||||||||
| SP3: | - |
Relevant External Links for IAPP Gene
- GeneLoc Exon Structure for
- IAPP
Expression for IAPP Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Mature Beta Cells Islets of Langerhans
- Islets of Langerhans
-
Epithelial Cells
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Neural Ectoderm (Nervous System)
- Neural Tube (Nervous System)
mRNA differential expression in normal tissues according to GTEx for IAPP Gene
This gene is overexpressed in Pancreas (x51.2).
This gene is overexpressed in Pancreas (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IAPP Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for IAPP
SOURCE GeneReport for Unigene cluster for IAPP Gene:
Hs.46835Evidence on tissue expression from TISSUES for IAPP Gene
- Pancreas(5)
- Nervous system(2.8)
- Blood(2.7)
- Muscle(2.3)
- Skin(2.2)
- Liver(2.2)
- Kidney(2.2)
- Intestine(2.2)
- Stomach(2.2)
- Heart(2.1)
Primer Products
-
OriGene qPCR primer pairs for IAPP
-
OriGene qPCR primer pairs and template standards for IAPP
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for IAPP Gene
Orthologs for IAPP Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | IAPP 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | IAPP 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Iapp 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Iapp 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | IAPP 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | IAPP 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | IAPP 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | IAPP 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | IAPP 31 |
|
OneToOne |
- Species where no ortholog for IAPP was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for IAPP Gene
- ENSEMBL:
- Gene Tree for IAPP (if available)
- TreeFam:
- Gene Tree for IAPP (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for IAPP: view image
Paralogs for IAPP Gene
Variants for IAPP Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for IAPP Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1800203 | - | p.Ser53Gly |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3628806 | CNV | loss | 21293372 |
| nsv1040888 | CNV | loss | 25217958 |
| nsv469161 | CNV | loss | 19166990 |
| nsv469162 | CNV | loss | 19166990 |
| nsv470274 | CNV | loss | 18288195 |
| nsv519603 | CNV | gain+loss | 19592680 |
| nsv557735 | CNV | loss | 21841781 |
| nsv557737 | CNV | loss | 21841781 |
| nsv557738 | CNV | loss | 21841781 |
| nsv557739 | CNV | loss | 21841781 |
| nsv557740 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
72.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.45;
9.89% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for IAPP Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IAPP Gene
Disorders for IAPP Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| insulinoma |
|
|
| hyperglycemia |
|
|
| islet cell tumor |
|
|
| amyloidosis |
|
|
| glucose intolerance |
|
Search IAPP in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for IAPP
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for IAPP Gene
Publications for IAPP Gene
- Missense mutation of amylin gene (S20G) in Japanese NIDDM patients. (PMID: 8772735) Sakagashira S … Nanjo K (Diabetes 1996) 3 4 23 41
- Cloning and expression of human islet amyloid polypeptide in cultured cells. (PMID: 17374526) Bhattacharya S … Singh S (Biochemical and biophysical research communications 2007) 3 4 23
- Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the severity of islet amyloidosis. (PMID: 15878744) Esapa C … Clark A (Biochimica et biophysica acta 2005) 3 23 41
- S20G mutation of the amylin gene is associated with a lower body mass index in Korean type 2 diabetic patients. (PMID: 12706321) Cho YM … Lee HK (Diabetes research and clinical practice 2003) 3 23 41
- Polymorphism in intron 2 of islet amyloid polypeptide gene is associated with lower low-density lipoprotein cholesterol in nondiabetic subjects and in type 2 diabetic patients. (PMID: 12588049) Rojas I … Novials A (Endocrine 2002) 3 23 41
ExternalLinks
Products for IAPP Gene
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- antibodies-online: Show 48 available IAPP Antibodies ranked by validation data
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- Recommended
- 63 WB Antibodies (anti-human)
- 18 IHC Antibodies (anti-human)
- 17 IHC (p) Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 15 WB Antibodies (anti-mouse)
- 4 IHC Antibodies (anti-mouse)
- 16 WB Antibodies (anti-rat)
- 5 IHC Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- antibodies-online: Show 87 available IAPP Elisa Kits ranked by validation data
- Compare Top IAPP Elisa Kits
- Quality Products:
- ABIN367162
- ABIN1873383
- ABIN1113372
- ABIN5522353
- ABIN454238
- ABIN1029052
- ABIN5593117
- ABIN770586
- ABIN626489
- ABIN1380920
- ABIN367878
- ABIN1873385
- ABIN1570441
- ABIN1884498
- ABIN5696493
- ABIN628030
- ABIN5593118
- ABIN772810
- ABIN4881297
- ABIN4881384
- ABIN431403
- ABIN1570442
- ABIN1884499
- ABIN5522354
- ABIN771488
- ABIN5593119
- ABIN627217
- ABIN4881342
- ABIN776216
- ABIN628728
- antibodies-online: Show 11 available IAPP Proteins ranked by validation data
- Compare Top IAPP Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for IAPP
- Search Santa Cruz Biotechnology (SCBT) for IAPP siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IAPP
- Horizon Cell Lines for IAPP
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for IAPP
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for IAPP
- Search GeneCopoeia for miRNA 3'UTR Target clone products for IAPP
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for IAPP
Sources for IAPP Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB