The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an imp... See more...

Aliases for HYOU1 Gene

Aliases for HYOU1 Gene

  • Hypoxia Up-Regulated 1 2 3 5
  • 170 KDa Glucose-Regulated Protein 3 4
  • 150 KDa Oxygen-Regulated Protein 3 4
  • Hypoxia Up-Regulated Protein 1 3 4
  • GRP-170 3 4
  • ORP-150 3 4
  • ORP150 3 4
  • Epididymis Secretory Sperm Binding Protein 3
  • Oxygen Regulated Protein (150kD) 3
  • Glucose-Regulated Protein 170 2
  • Grp170 3
  • HSP12A 3
  • GRP170 4
  • IMD59 3

External Ids for HYOU1 Gene

Previous GeneCards Identifiers for HYOU1 Gene

  • GC11P135580
  • GC11M120426
  • GC11M118948
  • GC11M118452
  • GC11M118420
  • GC11M114854
  • GC11M118914

Summaries for HYOU1 Gene

Entrez Gene Summary for HYOU1 Gene

  • The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

GeneCards Summary for HYOU1 Gene

HYOU1 (Hypoxia Up-Regulated 1) is a Protein Coding gene. Diseases associated with HYOU1 include Immunodeficiency 59 And Hypoglycemia and Hypoxia. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Unfolded Protein Response (UPR). Gene Ontology (GO) annotations related to this gene include chaperone binding. An important paralog of this gene is HSPA4.

UniProtKB/Swiss-Prot Summary for HYOU1 Gene

  • Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.

Gene Wiki entry for HYOU1 Gene

Additional gene information for HYOU1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HYOU1 Gene

Genomics for HYOU1 Gene

GeneHancer (GH) Regulatory Elements for HYOU1 Gene

Promoters and enhancers for HYOU1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J119055 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +0.3 333 3.4 FOXK2 HNRNPK ZBTB40 CTCF TCF12 NRF1 USF1 POLR2G SP1 RBAK VPS11 HYOU1 lnc-SLC37A4-3 lnc-VPS11-3 HINFP UBE4A ARCN1 RPS25 BCL9L ENSG00000254909
GH11J119066 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 500.4 -10.5 -10455 3.4 ZBTB40 ZNF217 EP300 SIN3A NRF1 TCF12 POLR2G USF1 SP1 PHF8 VPS11 ENSG00000272186 piR-33614-047 HYOU1 HMBS H2AX C2CD2L DPAGT1 SLC37A4 RPS25
GH11J118906 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 2.9 +138.1 138105 25.3 RXRA EP300 ZNF217 CTCF SIN3A NRF1 TCF12 MYC POLR2G USF1 BCL9L UPK2 DPAGT1 CCDC84 CXCR5 DDX6 VPS11 HMBS ENSG00000222529 FOXR1
GH11J119076 Enhancer 0.2 ENCODE 12.7 -20.7 -20683 2.5 VPS11 HMBS C2CD2L DPAGT1 HYOU1 ENSG00000255114 SLC37A4 RPS25 TRAPPC4 HINFP
GH11J119051 Enhancer 0.7 ENCODE 0.4 +5.3 5318 0.3 RELA POLR2A TCF12 ARNT NBN IKZF1 RB1 NR2F1 TAF1 MTA3 piR-50547 ENSG00000255114 HYOU1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HYOU1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HYOU1

Top Transcription factor binding sites by QIAGEN in the HYOU1 gene promoter:
  • MyoD
  • p53

Genomic Locations for HYOU1 Gene

Genomic Locations for HYOU1 Gene
chr11:119,044,185-119,057,246
(GRCh38/hg38)
Size:
13,062 bases
Orientation:
Minus strand
chr11:118,914,896-118,927,925
(GRCh37/hg19)
Size:
13,030 bases
Orientation:
Minus strand

Genomic View for HYOU1 Gene

Genes around HYOU1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HYOU1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HYOU1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HYOU1 Gene

Proteins for HYOU1 Gene

  • Protein details for HYOU1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y4L1-HYOU1_HUMAN
    Recommended name:
    Hypoxia up-regulated protein 1
    Protein Accession:
    Q9Y4L1
    Secondary Accessions:
    • A8C1Z0
    • B7Z909
    • Q2I204
    • Q53H25

    Protein attributes for HYOU1 Gene

    Size:
    999 amino acids
    Molecular mass:
    111335 Da
    Quaternary structure:
    • Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.

    Alternative splice isoforms for HYOU1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for HYOU1 Gene

Post-translational modifications for HYOU1 Gene

  • Glycosylation at Asn155, Asn222, Asn515, Thr580, Thr589, Thr590, Asn596, Asn830, Asn862, Asn869, Asn922, and Asn931
  • Ubiquitination at Lys398
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • HYOU1_HUMAN (1383)

No data available for DME Specific Peptides for HYOU1 Gene

Domains & Families for HYOU1 Gene

Gene Families for HYOU1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for HYOU1 Gene

Suggested Antigen Peptide Sequences for HYOU1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA, FLJ94899, Homo sapiens hypoxia up-regulated 1 (HYOU1), mRNA (A8C1Z0_HUMAN)
  • cDNA FLJ54708, highly similar to 150 kDa oxygen-regulated protein (Orp150) (B7Z909_HUMAN)
  • 170 kDa glucose-regulated protein (HYOU1_HUMAN)
  • HYOU1 protein (Q05D91_HUMAN)
  • HYOU1 protein (Q6IN67_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9Y4L1

UniProtKB/Swiss-Prot:

HYOU1_HUMAN :
  • Belongs to the heat shock protein 70 family.
Family:
  • Belongs to the heat shock protein 70 family.
genes like me logo Genes that share domains with HYOU1: view

Function for HYOU1 Gene

Molecular function for HYOU1 Gene

UniProtKB/Swiss-Prot Function:
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
UniProtKB/Swiss-Prot Induction:
By hypoxia and also by 2-deoxyglucose or tunicamycin.

Phenotypes From GWAS Catalog for HYOU1 Gene

Gene Ontology (GO) - Molecular Function for HYOU1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 26496610
GO:0005524 ATP binding IEA --
GO:0051087 chaperone binding ISS 10837345
genes like me logo Genes that share ontologies with HYOU1: view
genes like me logo Genes that share phenotypes with HYOU1: view

Human Phenotype Ontology for HYOU1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for HYOU1 Gene

MGI Knock Outs for HYOU1:

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for HYOU1 Gene

Localization for HYOU1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HYOU1 Gene

Endoplasmic reticulum lumen.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HYOU1 gene
Compartment Confidence
endoplasmic reticulum 5
extracellular 4
plasma membrane 2
cytoskeleton 2
mitochondrion 2
nucleus 2
endosome 2
cytosol 2
lysosome 2
golgi apparatus 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for HYOU1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005783 endoplasmic reticulum NAS 9020069
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0005790 smooth endoplasmic reticulum ISS --
GO:0005925 focal adhesion HDA 21423176
genes like me logo Genes that share ontologies with HYOU1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for HYOU1 Gene

Pathways & Interactions for HYOU1 Gene

genes like me logo Genes that share pathways with HYOU1: view

SIGNOR curated interactions for HYOU1 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for HYOU1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002931 response to ischemia ISS --
GO:0006888 ER to Golgi vesicle-mediated transport IDA 10837345
GO:0006898 receptor-mediated endocytosis TAS --
GO:0034976 response to endoplasmic reticulum stress IEP 9020069
GO:0036498 IRE1-mediated unfolded protein response TAS --
genes like me logo Genes that share ontologies with HYOU1: view

Drugs & Compounds for HYOU1 Gene

(8) Drugs for HYOU1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(6) Additional Compounds for HYOU1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with HYOU1: view

Transcripts for HYOU1 Gene

mRNA/cDNA for HYOU1 Gene

2 REFSEQ mRNAs :
25 NCBI additional mRNA sequence :
23 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HYOU1 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^
SP1: - - - -
SP2: - - - - -
SP3: - - - - - - - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: -
SP7: - -
SP8: - - -
SP9:
SP10:

ExUns: 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29a · 29b
SP1: - -
SP2: - -
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for HYOU1 Gene

GeneLoc Exon Structure for
HYOU1

Expression for HYOU1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HYOU1 Gene

mRNA differential expression in normal tissues according to GTEx for HYOU1 Gene

This gene is overexpressed in Liver (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HYOU1 Gene



Protein tissue co-expression partners for HYOU1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HYOU1

SOURCE GeneReport for Unigene cluster for HYOU1 Gene:

Hs.277704

mRNA Expression by UniProt/SwissProt for HYOU1 Gene:

Q9Y4L1-HYOU1_HUMAN
Tissue specificity: Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.

Evidence on tissue expression from TISSUES for HYOU1 Gene

  • Nervous system(5)
  • Liver(4.7)
  • Blood(4.4)
  • Heart(4.4)
  • Bone marrow(4.3)
  • Kidney(3.9)
  • Lung(3.9)
  • Intestine(3.3)
  • Pancreas(2.6)
  • Spleen(2.3)
  • Lymph node(2.2)
  • Skin(2.1)
  • Thyroid gland(2)
genes like me logo Genes that share expression patterns with HYOU1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for HYOU1 Gene

Orthologs for HYOU1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for HYOU1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia HYOU1 31 30
  • 99.14 (n)
OneToOne
dog
(Canis familiaris)
Mammalia HYOU1 31 30
  • 89.46 (n)
OneToOne
cow
(Bos Taurus)
Mammalia HYOU1 31 30
  • 89.31 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Hyou1 30
  • 88.21 (n)
mouse
(Mus musculus)
Mammalia Hyou1 17 31 30
  • 87.55 (n)
oppossum
(Monodelphis domestica)
Mammalia HYOU1 31
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 26 (a)
ManyToMany
chicken
(Gallus gallus)
Aves HYOU1 31 30
  • 69.35 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia HYOU1 31
  • 69 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia hyou1 30
  • 67.8 (n)
Str.3875 30
African clawed frog
(Xenopus laevis)
Amphibia LOC398531 30
zebrafish
(Danio rerio)
Actinopterygii hyou1 31 30
  • 67.31 (n)
OneToOne
Dr.17462 30
fruit fly
(Drosophila melanogaster)
Insecta CG2918 31 30
  • 54.34 (n)
OneToOne
EG:25E8.1 32
  • 43 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001827 30
  • 54.22 (n)
worm
(Caenorhabditis elegans)
Secernentea T14G8.3 31 32 30
  • 49.73 (n)
OneToMany
T24H7.2 31 32
  • 34 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SSE1 31
  • 27 (a)
ManyToMany
SSE2 31
  • 25 (a)
ManyToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G16660 30
  • 47.8 (n)
rice
(Oryza sativa)
Liliopsida Os02g0710900 30
  • 47.36 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9387 31
  • 43 (a)
OneToOne
Cin.4458 30
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4458 30
Species where no ortholog for HYOU1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HYOU1 Gene

ENSEMBL:
Gene Tree for HYOU1 (if available)
TreeFam:
Gene Tree for HYOU1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for HYOU1: view image

Paralogs for HYOU1 Gene

(10) SIMAP similar genes for HYOU1 Gene using alignment to 14 proteins:

  • HYOU1_HUMAN
  • B7Z909_HUMAN
  • E9PJ21_HUMAN
  • E9PL22_HUMAN
  • J3KSJ2_HUMAN
  • J3KSR2_HUMAN
  • J3KT27_HUMAN
  • J3KTF1_HUMAN
  • J3QL06_HUMAN
  • J3QLE9_HUMAN
  • J3QQH7_HUMAN
  • Q05D91_HUMAN
  • Q6IN67_HUMAN
  • Q9BST8_HUMAN
genes like me logo Genes that share paralogs with HYOU1: view

Variants for HYOU1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HYOU1 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
636750 Uncertain Significance: not provided 119,055,026(-) T/C MISSENSE_VARIANT
719363 Benign: not provided 119,048,848(-) G/A SYNONYMOUS_VARIANT
724765 Benign: not provided 119,047,970(-) G/C SYNONYMOUS_VARIANT
730491 Likely Benign: not provided 119,048,548(-) T/A SYNONYMOUS_VARIANT
731881 Benign: not provided 119,055,740(-) C/A INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for HYOU1 Gene

Structural Variations from Database of Genomic Variants (DGV) for HYOU1 Gene

Variant ID Type Subtype PubMed ID
nsv819696 CNV loss 19587683
nsv952745 CNV deletion 24416366

Variation tolerance for HYOU1 Gene

Residual Variation Intolerance Score: 6.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.97; 36.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for HYOU1 Gene

Human Gene Mutation Database (HGMD)
HYOU1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
HYOU1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HYOU1 Gene

Disorders for HYOU1 Gene

MalaCards: The human disease database

(7) MalaCards diseases for HYOU1 Gene - From: OMIM, ClinVar, GTR, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
immunodeficiency 59 and hypoglycemia
  • imd59
hypoxia
ischemia
  • acute coronary syndrome
hypoglycemia
  • hypoglycaemia
granulocytopenia
  • agranulocytosis
- elite association - COSMIC cancer census association via MalaCards
Search HYOU1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

HYOU1_HUMAN
  • Immunodeficiency 59 and hypoglycemia (IMD59) [MIM:233600]: An autosomal recessive primary immunologic disorder characterized by combined immunodeficiency, granulocytopenia, B-cell and dendritic cell deficiency, recurrent septic infections of the respiratory tract, skin and mucous membranes, and disturbed glucose metabolism. {ECO:0000269 PubMed:27913302}. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Additional Disease Information for HYOU1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with HYOU1: view

No data available for Genatlas for HYOU1 Gene

Publications for HYOU1 Gene

  1. 150-kDa oxygen-regulated protein (ORP150) suppresses hypoxia-induced apoptotic cell death. (PMID: 10037731) Ozawa K … Tohyama M (The Journal of biological chemistry 1999) 2 3 4 23 54
  2. Cloning and expression of cDNA encoding the human 150 kDa oxygen-regulated protein, ORP150. (PMID: 9020069) Ikeda J … Yanagi H (Biochemical and biophysical research communications 1997) 2 3 4 23 54
  3. Molecular cloning, sequence, function and structural basis of human heart 150 kDa oxygen-regulated protein, an ER chaperone. (PMID: 17131193) Takeuchi S (The protein journal 2006) 3 4 23 54
  4. Production of three distinct mRNAs of 150 kDa oxygen-regulated protein (ORP150) by alternative promoters: preferential induction of one species under stress conditions. (PMID: 10965054) Kaneda S … Yanagi H (Journal of biochemistry 2000) 3 4 23 54
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41 54

Products for HYOU1 Gene

  • Signalway ELISA kits for HYOU1
  • Signalway Proteins for HYOU1

Sources for HYOU1 Gene