Aliases for HYI Gene
Previous GeneCards Identifiers for HYI Gene
This gene encodes a putative hydroxypyruvate isomerase, which likely catalyzes the conversion of hydroxypyruvate to 2-hydroxy-3-oxopropanoate, and may be involved in carbohydrate transport and metabolism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for HYI Gene
HYI (Hydroxypyruvate Isomerase (Putative)) is a Protein Coding gene. Diseases associated with HYI include Hydrolethalus Syndrome 1 and Arthrogryposis, Renal Dysfunction, And Cholestasis 1. Among its related pathways are Glyoxylate and dicarboxylate metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include hydroxypyruvate isomerase activity.
UniProtKB/Swiss-Prot Summary for HYI Gene
Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).