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Aliases for HTRA3 Gene
Aliases for HTRA3 Gene
External Ids for HTRA3 Gene
- HGNC: 30406
- Entrez Gene: 94031
- Ensembl: ENSG00000170801
- OMIM: 608785
- UniProtKB: P83110
Previous GeneCards Identifiers for HTRA3 Gene
- GC04P008238
- GC04P008421
- GC04P008464
- GC04P008389
- GC04P008271
- GC04P008191
Summaries for HTRA3 Gene
GeneCards Summary for HTRA3 Gene
HTRA3 (HtrA Serine Peptidase 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and endopeptidase activity. An important paralog of this gene is HTRA1.
UniProtKB/Swiss-Prot Summary for HTRA3 Gene
-
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (PubMed:21321049, PubMed:22229724).
Additional gene information for HTRA3 Gene
- HGNC(30406)
- Entrez Gene(94031)
- Ensembl(ENSG00000170801)
- OMIM(608785)
- UniProtKB(P83110)
- Open Targets Platform(ENSG00000170801)
- Search for HTRA3 at DataMed
- Search for HTRA3 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HTRA3 Gene
Genomics for HTRA3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HTRA3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HTRA3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HTRA3
- Top Transcription factor binding sites by QIAGEN in the HTRA3 gene promoter:
-
- AhR
- ATF-2
- Bach2
- c-Jun
- c-Myc
- GR
- GR-alpha
- GR-beta
- NF-kappaB1
- Zic3
Genomic Locations for HTRA3 Gene
Genomic Locations for HTRA3 Gene
- chr4:8,269,712-8,307,098
- (GRCh38/hg38)
- Size:
- 37,387 bases
- Orientation:
- Plus strand
- chr4:8,271,489-8,308,838
- (GRCh37/hg19)
- Size:
- 37,350 bases
- Orientation:
- Plus strand
Genomic View for HTRA3 Gene
Genes around HTRA3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.1 by HGNC
- 4p16.1 by Entrez Gene
- 4p16.1 by Ensembl
HTRA3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HTRA3 Gene
Proteins for HTRA3 Gene
-
Protein details for HTRA3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P83110-HTRA3_HUMAN
- Recommended name:
- Serine protease HTRA3
- Protein Accession:
- P83110
- Q7Z7A2
Protein attributes for HTRA3 Gene
- Size:
- 453 amino acids
- Molecular mass:
- 48608 Da
- Quaternary structure:
-
- Homotrimer (PubMed:26110759). Interacts with TGFB1; the interaction inhibits TGFB-mediated signaling. Interacts with BMP4; the interaction inhibits BMP4-mediated signaling. Interacts with TGFB2 and GDF5 (By similarity). Interacts with MYH9.
Protein Expression for HTRA3 Gene
Selected DME Specific Peptides for HTRA3 Gene
- P83110:
-
- GEVIGINT
- GNSGGPL
- NFIADVVEK
- GSPFALQNT
Post-translational modifications for HTRA3 Gene
Other Protein References for HTRA3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences HTRA3 Antibody
-
Custom Antibody ServicesOriGene Antibodies for HTRA3
- Novus Biologicals Antibodies for HTRA3
-
Abcam antibodies for HTRA3
- Invitrogen Antibodies for HTRA3 (AFLGC-HTRA3)
-
Boster Bio Antibodies for HTRA3
- Sino Biological Antibodies for HTRA3
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HTRA3
- Origene Custom Protein Services for HTRA3
- Novus Biologicals proteins for HTRA3
- antibodies-online: Show 7 available HTRA3 Proteins ranked by validation data
- Compare Top HTRA3 Proteins
-
Quality Products:
-
Abcam proteins for HTRA3
Assay Products
Domains & Families for HTRA3 Gene
Gene Families for HTRA3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted secreted proteins
Protein Domains for HTRA3 Gene
- InterPro:
- Blocks:
-
- PDZ/DHR/GLGF domain
- Protease inhibitor, Kazal-type
- HtrA/DegQ protease family signature
- ProtoNet:
Suggested Antigen Peptide Sequences for HTRA3 Gene
- GenScript: Design optimal peptide antigens:
-
- Pregnancy-related serine protease (HTRA3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P83110- Family:
-
- Belongs to the peptidase S1C family.
Function for HTRA3 Gene
Molecular function for HTRA3 Gene
- UniProtKB/Swiss-Prot Function:
- Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (PubMed:21321049, PubMed:22229724).
- UniProtKB/Swiss-Prot Induction:
- Down-regulated in ovarian and endometrial cancers (EC). Decrease of 3.2-fold in endometrial cancer.
Enzyme Numbers (IUBMB) for HTRA3 Gene
Phenotypes From GWAS Catalog for HTRA3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004175 | endopeptidase activity | IDA | 18387192 |
| GO:0004252 | serine-type endopeptidase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 22229724 |
| GO:0005520 | insulin-like growth factor binding | IEA | -- |
| GO:0008233 | peptidase activity | IEA | -- |
Phenotypes for HTRA3 Gene
- GenomeRNAi human phenotypes for HTRA3:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Decreased viability in non-small-cell lung cancer (NSCLC) lineage
- Decreased Sindbis virus (SINV) infection
- Inconclusive
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Increased epidermal growth factor (EGF) endocytosis, decreased endosome-nucleus distance (endosomes clustered in the perinuclear region)
Animal Model Products
-
Taconic Biosciences Mouse Models for HTRA3
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HTRA3 - Select products 50% OFF >
- * HTRA3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HTRA3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HTRA3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HTRA3
miRNA for HTRA3 Gene
- miRTarBase miRNAs that target HTRA3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HTRA3
- Browse OriGene Inhibitory RNA Products For HTRA3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HTRA3
Clone Products
- Applied Biological Materials (abm): Clones for HTRA3 - Select products 50% OFF >
- * HTRA3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HTRA3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HTRA3
Cell Line Products
-
Horizon Cell Lines for HTRA3
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HTRA3 Gene
Localization for HTRA3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HTRA3 Gene
- Secreted. Note=Secretion increased during decidualization of endometrial stromal cells.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| plasma membrane | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| cytosol | 1 |
| endoplasmic reticulum | 0 |
| lysosome | 0 |
| golgi apparatus | 0 |
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
Pathways & Interactions for HTRA3 Gene
Interacting Proteins for HTRA3 Gene
Selected Interacting proteins:
P83110-HTRA3_HUMAN
ENSP00000303766
for HTRA3 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for HTRA3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IDA | 18387192 |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | ISS | -- |
| GO:0030514 | negative regulation of BMP signaling pathway | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for HTRA3 Gene
Transcripts for HTRA3 Gene
mRNA/cDNA for HTRA3 Gene
- 2 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000307358 2539 nts (view in UCSC)
- ENST00000382512 2023 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HTRA3 - Select products 50% OFF >
- * HTRA3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HTRA3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HTRA3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HTRA3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HTRA3
- Browse OriGene Inhibitory RNA Products For HTRA3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HTRA3
Clone Products
- Applied Biological Materials (abm): Clones for HTRA3 - Select products 50% OFF >
- * HTRA3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HTRA3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HTRA3
Relevant External Links for HTRA3 Gene
- GeneLoc Exon Structure for
- HTRA3
Expression for HTRA3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Lens Vesicle Cells Lens Vesicle
- Lens
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for HTRA3 Gene
This gene is overexpressed in Heart - Atrial Appendage (x7.8).
This gene is overexpressed in Bone marrow mesenchymal stem cell (32.5), Heart (25.8), and Peripheral blood mononuclear cells (10.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HTRA3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HTRA3
SOURCE GeneReport for Unigene cluster for HTRA3 Gene:
Hs.479119mRNA Expression by UniProt/SwissProt for HTRA3 Gene:
P83110-HTRA3_HUMAN
Tissue specificity:
Widely expressed, with highest levels in both adult and fetal heart, ovary, uterus placenta, and bladder. In the endometrium, expressed in epithelial glands and the stroma. Also present in leukocytes. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney.
Evidence on tissue expression from TISSUES for HTRA3 Gene
- Heart(4.4)
- Nervous system(4.1)
Primer Products
-
OriGene qPCR primer pairs for HTRA3
-
OriGene qPCR primer pairs and template standards for HTRA3
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for HTRA3 Gene
Orthologs for HTRA3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HTRA3 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | HTRA3 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Htra3 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Htra3 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | HTRA3 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | HTRA3 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | HTRA3 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | HTRA3 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | HTRA3 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | htra3 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC573378 30 |
|
||
| HTRA3 (1 of 3) 31 |
|
OneToMany | |||
| htra3a 31 |
|
OneToMany | |||
| HTRA3 (3 of 3) 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG8464 32 |
|
|
|
| HtrA2 31 |
|
OneToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for HTRA3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for HTRA3 Gene
- ENSEMBL:
- Gene Tree for HTRA3 (if available)
- TreeFam:
- Gene Tree for HTRA3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HTRA3: view image
Paralogs for HTRA3 Gene
Variants for HTRA3 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv8956n54 | CNV | gain | 21841781 |
| dgv8957n54 | CNV | gain | 21841781 |
| esv1430054 | CNV | insertion | 17803354 |
| esv1923424 | CNV | deletion | 18987734 |
| esv2493897 | CNV | insertion | 19546169 |
| esv2727109 | CNV | deletion | 23290073 |
| esv29195 | CNV | loss | 19812545 |
| esv34196 | OTHER | inversion | 12058347 |
| esv3569280 | CNV | loss | 25503493 |
| esv3575676 | CNV | gain | 25503493 |
| esv3599544 | CNV | loss | 21293372 |
| nsv1002794 | CNV | gain | 25217958 |
| nsv1009011 | CNV | loss | 25217958 |
| nsv1073303 | CNV | deletion | 25765185 |
| nsv1125239 | CNV | insertion | 24896259 |
| nsv1132929 | CNV | insertion | 24896259 |
| nsv1136815 | CNV | deletion | 24896259 |
| nsv1142385 | CNV | tandem duplication | 24896259 |
| nsv1145025 | CNV | deletion | 24896259 |
| nsv4222 | CNV | insertion | 18451855 |
| nsv461216 | CNV | loss | 19166990 |
| nsv461218 | CNV | loss | 19166990 |
| nsv593626 | CNV | loss | 21841781 |
| nsv593627 | CNV | gain | 21841781 |
| nsv593628 | CNV | loss | 21841781 |
| nsv593634 | CNV | loss | 21841781 |
| nsv593635 | CNV | gain+loss | 21841781 |
| nsv593636 | CNV | loss | 21841781 |
| nsv829853 | CNV | gain+loss | 17160897 |
| nsv949784 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
34% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.85;
48.11% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HTRA3 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HTRA3 Gene
Disorders for HTRA3 Gene
Additional Disease Information for HTRA3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for HTRA3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HTRA3 Gene
Publications for HTRA3 Gene
- Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2. (PMID: 12513693) Nie GY … Salamonsen LA (The Biochemical journal 2003) 2 3 4 23
- Expression of human HtrA1, HtrA2, HtrA3 and TGF-beta1 genes in primary endometrial cancer. (PMID: 19424634) Narkiewicz J … Lipinska B (Oncology reports 2009) 3 4 23
- Serine proteases HTRA1 and HTRA3 are down-regulated with increasing grades of human endometrial cancer. (PMID: 16650464) Bowden MA … Nie G (Gynecologic oncology 2006) 3 4 23
- Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains. (PMID: 26110759) Glaza P … Lipinska B (PloS one 2015) 3 4
- Application of the wheat-germ cell-free translation system to produce high temperature requirement A3 (HtrA3) proteases. (PMID: 22229724) Singh H … Nie G (BioTechniques 2012) 3 4
ExternalLinks
Products for HTRA3 Gene
- Custom Antibody ServicesOriGene Antibodies for HTRA3
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HTRA3
- Origene Custom Protein Services for HTRA3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HTRA3
- Browse OriGene Inhibitory RNA Products For HTRA3
- OriGene qPCR primer pairs for HTRA3
- OriGene qPCR primer pairs and template standards for HTRA3
- OriGene CRISPR knockouts for HTRA3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HTRA3
- Sino Biological Human cDNA Clone for HTRA3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for HTRA3
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for HTRA3
- Novus Biologicals proteins for HTRA3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for HTRA3
- Abcam proteins for HTRA3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for HTRA3
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for HTRA3 (AFLGC-HTRA3)
- VectorBuilder Custom and pre-made DNA vectors for HTRA3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for HTRA3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HTRA3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HTRA3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HTRA3
- antibodies-online: Show 22 available HTRA3 Antibodies ranked by validation data
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- antibodies-online: Show 16 available HTRA3 Elisa Kits ranked by validation data
- Compare Top HTRA3 Elisa Kits
- Quality Products:
- antibodies-online: Show 7 available HTRA3 Proteins ranked by validation data
- Compare Top HTRA3 Proteins
- Quality Products:
- Horizon Cell Lines for HTRA3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HTRA3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HTRA3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HTRA3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HTRA3
- Boster Bio Antibodies for HTRA3
- Browse Boster Bio ELISA Kits
Sources for HTRA3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
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