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HSP90AB3P Gene(Pseudogene)

Heat Shock Protein 90 Alpha Family Class B Member 3, Pseudogene

GCID:
GC04P087891
GIFtS:
22
Genes Participants
UDN Logo

Aliases for HSP90AB3P Gene

Aliases for HSP90AB3P Gene

  • Heat Shock Protein 90 Alpha Family Class B Member 3, Pseudogene 2 3 5
  • Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 3, Pseudogene 2 3
  • Heat Shock 90kDa Protein 1, Beta Pseudogene 1 2 3
  • Heat Shock 90kD Protein 1, Beta Pseudogene 1 2 3
  • Heat Shock Protein 90Bc 3 4
  • HSP90BC 3 4
  • Heat Shock Protein 90kDa Alpha Family Class B Member 3, Pseudogene 3
  • Heat Shock Protein 90-Beta C 4
  • HSPCP1 3

External Ids for HSP90AB3P Gene

Previous HGNC Symbols for HSP90AB3P Gene

  • HSPCP1

Previous GeneCards Identifiers for HSP90AB3P Gene

  • GC04P089031
  • GC04P088812

Summaries for HSP90AB3P Gene

GeneCards Summary for HSP90AB3P Gene

HSP90AB3P (Heat Shock Protein 90 Alpha Family Class B Member 3, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include unfolded protein binding.

UniProtKB/Swiss-Prot for HSP90AB3P Gene

  • Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

Additional gene information for HSP90AB3P Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSP90AB3P Gene

Genomics for HSP90AB3P Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for HSP90AB3P Gene

Promoters and enhancers for HSP90AB3P Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH04J088106 Enhancer 1.2 Ensembl ENCODE 5.1 +216.5 216485 4.2 PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ETS1 YY1 NFKBIZ RNU6-818P RNU6ATAC31P SPP1 HSP90AB3P PKD2 GC04P088089 RPL31P24 ABCG2
GH04J088096 Enhancer 0.2 dbSUPER 5.1 +207.6 207630 6.2 SPP1 PKD2 RNU6-818P RNU6ATAC31P HSP90AB3P GC04P088089 RPL31P24 ABCG2
GH04J087895 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.7 +4.8 4820 1.6 JUN CEBPG POLR2A SMC3 RCOR1 CHD2 TCF7L2 CEBPB HMG20A REST SPP1 PKD2 HSP90AB3P PIR37483
GH04J087864 Enhancer 1.1 Ensembl ENCODE 0.3 -25.0 -24992 5 FOXA2 MLX ARID4B SIN3A DMAP1 ETS1 YY1 NFKBIZ RXRA SP5 SPP1 ENSG00000249001 ENSG00000272856 PKD2 HSP90AB3P MEPE
GH04J087849 Enhancer 0.9 FANTOM5 Ensembl 0.3 -41.9 -41861 0.6 SMARCE1 CTCF CEBPB CEBPG GABPA CTBP1 CEBPA HMBOX1 MYC SPP1 IBSP HSD17B11 MEPE HSP90AB3P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HSP90AB3P on UCSC Golden Path with GeneCards custom track

Genomic Locations for HSP90AB3P Gene

Genomic Locations for HSP90AB3P Gene
chr4:87,891,748-87,894,288
(GRCh38/hg38)
Size:
2,541 bases
Orientation:
Plus strand
chr4:88,812,995-88,815,167
(GRCh37/hg19)
Size:
2,173 bases
Orientation:
Plus strand

Genomic View for HSP90AB3P Gene

Genes around HSP90AB3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HSP90AB3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HSP90AB3P Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for HSP90AB3P Gene

Proteins for HSP90AB3P Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for HSP90AB3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q58FF7-H90B3_HUMAN
    Recommended name:
    Putative heat shock protein HSP 90-beta-3
    Protein Accession:
    Q58FF7

    Protein attributes for HSP90AB3P Gene

    Size:
    597 amino acids
    Molecular mass:
    68325 Da
    Quaternary structure:
    • Homodimer.

neXtProt entry for HSP90AB3P Gene

Protein Expression for HSP90AB3P Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for HSP90AB3P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for HSP90AB3P Gene

Domains & Families for HSP90AB3P Gene

Protein Domains for HSP90AB3P Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for HSP90AB3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q58FF7

UniProtKB/Swiss-Prot:

H90B3_HUMAN :
  • The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
  • Belongs to the heat shock protein 90 family.
Domain:
  • The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
Family:
  • Belongs to the heat shock protein 90 family.
genes like me logo Genes that share domains with HSP90AB3P: view

No data available for Gene Families for HSP90AB3P Gene

Function for HSP90AB3P Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for HSP90AB3P Gene

UniProtKB/Swiss-Prot Function:
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.

Phenotypes From GWAS Catalog for HSP90AB3P Gene

Gene Ontology (GO) - Molecular Function for HSP90AB3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005524 ATP binding IEA --
GO:0051082 unfolded protein binding IEA --
genes like me logo Genes that share ontologies with HSP90AB3P: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90AB3P Gene

Localization for HSP90AB3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for HSP90AB3P Gene

Cytoplasm.

Gene Ontology (GO) - Cellular Components for HSP90AB3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0070062 extracellular exosome HDA 23533145
genes like me logo Genes that share ontologies with HSP90AB3P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for HSP90AB3P Gene

Pathways & Interactions for HSP90AB3P Gene

SuperPathways for HSP90AB3P Gene

PathCards logo More details on SuperPathways for HSP90AB3P
No Data Available

Interacting Proteins for HSP90AB3P Gene

Selected Interacting proteins: Q58FF7-H90B3_HUMAN for HSP90AB3P Gene via IID

Gene Ontology (GO) - Biological Process for HSP90AB3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006457 protein folding IEA --
GO:0006950 response to stress IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with HSP90AB3P: view

No data available for Pathways by source and SIGNOR curated interactions for HSP90AB3P Gene

Drugs & Compounds for HSP90AB3P Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for HSP90AB3P Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for HSP90AB3P Gene

(1) Additional mRNA sequences :
(35) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HSP90AB3P Gene

Heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HSP90AB3P Gene

No ASD Table

Relevant External Links for HSP90AB3P Gene

GeneLoc Exon Structure for
HSP90AB3P
ECgene alternative splicing isoforms for
HSP90AB3P

Expression for HSP90AB3P Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HSP90AB3P Gene

mRNA expression in normal human tissues for HSP90AB3P Gene
mRNA expression by GTEx for HSP90AB3P Gene

Protein differential expression in normal tissues from HIPED for HSP90AB3P Gene

This gene is overexpressed in Plasma (17.8), Liver, secretome (13.8), Cervix (9.2), NK cells (8.7), and Peripheral blood mononuclear cells (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HSP90AB3P Gene



NURSA nuclear receptor signaling pathways regulating expression of HSP90AB3P Gene:

HSP90AB3P

SOURCE GeneReport for Unigene cluster for HSP90AB3P Gene:

Hs.744112
genes like me logo Genes that share expression patterns with HSP90AB3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HSP90AB3P Gene

Orthologs for HSP90AB3P Gene

Evolution for HSP90AB3P Gene

ENSEMBL:
Gene Tree for HSP90AB3P (if available)
TreeFam:
Gene Tree for HSP90AB3P (if available)

No data available for Orthologs for HSP90AB3P Gene

Paralogs for HSP90AB3P Gene

(12) SIMAP similar genes for HSP90AB3P Gene using alignment to 1 proteins:

  • H90B3_HUMAN
genes like me logo Genes that share paralogs with HSP90AB3P: view

No data available for Paralogs for HSP90AB3P Gene

Variants for HSP90AB3P Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Additional Variant Information for HSP90AB3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HSP90AB3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for HSP90AB3P Gene

Disorders for HSP90AB3P Gene

Additional Disease Information for HSP90AB3P

Genetic Association Database
(GAD)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for HSP90AB3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90AB3P Gene

Publications for HSP90AB3P Gene

  1. The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B … Monteiro A (Genomics 2005) 2 3 4 58
  2. Assignment of an intron-containing human heat-shock protein gene (hsp90 beta, HSPCB) to chromosome 6 near TCTE1 (6p21) and two intronless pseudogenes to chromosomes 4 and 15 by polymerase chain reaction amplification from a panel of hybrid cell lines. (PMID: 8288256) Durkin AS … Nierman WC (Genomics 1993) 2 3 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. (PMID: 27173435) Boldt K … UK10K Rare Diseases Group (Nature communications 2016) 3 58
  5. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. (PMID: 25756610) Papp SJ … Lamia KA (eLife 2015) 3 58

Products for HSP90AB3P Gene

Sources for HSP90AB3P Gene

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