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Aliases for HSP90AB3P Gene
Aliases for HSP90AB3P Gene
External Ids for HSP90AB3P Gene
- HGNC: 5259
- Entrez Gene: 3327
- Ensembl: ENSG00000183199
- UniProtKB: Q58FF7
Previous HGNC Symbols for HSP90AB3P Gene
- HSPCP1
Previous GeneCards Identifiers for HSP90AB3P Gene
- GC04P089031
- GC04P088812
Summaries for HSP90AB3P Gene
GeneCards Summary for HSP90AB3P Gene
HSP90AB3P (Heat Shock Protein 90 Alpha Family Class B Member 3, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include unfolded protein binding.
UniProtKB/Swiss-Prot Summary for HSP90AB3P Gene
-
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
Additional gene information for HSP90AB3P Gene
- HGNC(5259)
- Entrez Gene(3327)
- Ensembl(ENSG00000183199)
- UniProtKB(Q58FF7)
- Open Targets Platform(ENSG00000183199)
- Search for HSP90AB3P at DataMed
- Search for HSP90AB3P at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HSP90AB3P Gene
Genomics for HSP90AB3P Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HSP90AB3P Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH04J087891 | Promoter | 0.3 | Ensembl | 600.7 | -0.6 | -647 | 0.2 | HSP90AB3P lnc-MEPE-1 piR-50968-096 SPP1 MEPE | ||
| GH04J088104 | Enhancer | 1.1 | Ensembl ENCODE | 5.1 | +215.6 | 215611 | 5.9 | GATAD2A PRDM10 REST ZNF629 SOX13 NFKBIZ ZNF692 RCOR2 FOXA1 RXRB | RNU6-818P RNU6ATAC31P PKD2 SPP1 HSP90AB3P lnc-PKD2-1 piR-60885-094 ABCG2 | |
| GH04J088100 | Enhancer | 0.4 | Ensembl dbSUPER | 5.1 | +209.8 | 209753 | 1.4 | SPI1 | RNU6-818P RNU6ATAC31P HSP90AB3P lnc-PKD2-1 piR-60885-094 PKD2 ABCG2 | |
| GH04J088044 | Enhancer | 0.2 | Ensembl | 5.9 | +153.5 | 153453 | 2 | RNU6-818P PKD2 HSP90AB3P hsa-miR-5095-372 piR-31199-267 ABCG2 | ||
| GH04J088069 | Enhancer | 0.2 | Ensembl | 5.5 | +178.2 | 178153 | 1.4 | PKD2 RNU6-818P HSP90AB3P piR-61945-389 hsa-miR-5095-372 ABCG2 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HSP90AB3P on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for HSP90AB3P Gene
Genomic Locations for HSP90AB3P Gene
- chr4:87,891,748-87,894,288
- (GRCh38/hg38)
- Size:
- 2,541 bases
- Orientation:
- Plus strand
- chr4:88,812,995-88,815,167
- (GRCh37/hg19)
- Size:
- 2,173 bases
- Orientation:
- Plus strand
Genomic View for HSP90AB3P Gene
Genes around HSP90AB3P on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q22.1 by HGNC
- 4q22.1 by Entrez Gene
- 4q22.1 by Ensembl
HSP90AB3P Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HSP90AB3P Gene
Proteins for HSP90AB3P Gene
-
Protein details for HSP90AB3P Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q58FF7-H90B3_HUMAN
- Recommended name:
- Putative heat shock protein HSP 90-beta-3
- Protein Accession:
- Q58FF7
Protein attributes for HSP90AB3P Gene
- Size:
- 597 amino acids
- Molecular mass:
- 68325 Da
- Quaternary structure:
-
- Homodimer.
Protein Expression for HSP90AB3P Gene
Post-translational modifications for HSP90AB3P Gene
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HSP90AB3P
- Origene Custom Protein Services for HSP90AB3P
No data available for DME Specific Peptides for HSP90AB3P Gene
Domains & Families for HSP90AB3P Gene
Protein Domains for HSP90AB3P Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HSP90AB3P Gene
- GenScript: Design optimal peptide antigens:
-
- Heat shock protein 90-beta c (H90B3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q58FF7UniProtKB/Swiss-Prot:
H90B3_HUMAN :- The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
- Belongs to the heat shock protein 90 family.
- Domain:
-
- The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins.
- Family:
-
- Belongs to the heat shock protein 90 family.
No data available for Gene Families for HSP90AB3P Gene
Function for HSP90AB3P Gene
Molecular function for HSP90AB3P Gene
- UniProtKB/Swiss-Prot Function:
- Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
Phenotypes From GWAS Catalog for HSP90AB3P Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0005524 | ATP binding | IBA | 21873635 |
| GO:0051082 | unfolded protein binding | IBA | 21873635 |
| GO:0097718 | disordered domain specific binding | IBA | 21873635 |
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HSP90AB3P - Select products 50% OFF >
- * HSP90AB3P CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for HSP90AB3P
miRNA Products
Inhibitory RNA Products
Clone Products
No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HSP90AB3P Gene
Localization for HSP90AB3P Gene
Subcellular locations from UniProtKB/Swiss-Prot for HSP90AB3P Gene
- Cytoplasm.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005829 | cytosol | IBA | 21873635 |
| GO:0005886 | plasma membrane | IBA | 21873635 |
| GO:0009986 | cell surface | IBA | 21873635 |
| GO:0032991 | protein-containing complex | IBA | 21873635 |
No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for HSP90AB3P Gene
Pathways & Interactions for HSP90AB3P Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006457 | protein folding | IBA | 21873635 |
| GO:0008150 | biological_process | ND | -- |
| GO:0034605 | cellular response to heat | IBA | 21873635 |
| GO:0050821 | protein stabilization | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for HSP90AB3P Gene
Transcripts for HSP90AB3P Gene
mRNA/cDNA for HSP90AB3P Gene
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000505987 2173 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HSP90AB3P - Select products 50% OFF >
- * HSP90AB3P CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for HSP90AB3P
miRNA Products
Inhibitory RNA Products
Clone Products
Relevant External Links for HSP90AB3P Gene
- GeneLoc Exon Structure for
- HSP90AB3P
Expression for HSP90AB3P Gene
This gene is overexpressed in Plasma (17.8), Liver, secretome (13.8), Cervix (9.2), NK cells (8.7), and Peripheral blood mononuclear cells (8.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HSP90AB3P Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HSP90AB3P
SOURCE GeneReport for Unigene cluster for HSP90AB3P Gene:
Hs.744112Primer Products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HSP90AB3P Gene
Orthologs for HSP90AB3P Gene
No data available for Orthologs for HSP90AB3P Gene
Paralogs for HSP90AB3P Gene
(12) SIMAP similar genes for HSP90AB3P Gene using alignment to 1 proteins:
- H90B3_HUMAN
No data available for Paralogs for HSP90AB3P Gene
Variants for HSP90AB3P Gene
Additional Variant Information for HSP90AB3P Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HSP90AB3P
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for HSP90AB3P Gene
Disorders for HSP90AB3P Gene
Additional Disease Information for HSP90AB3P
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for HSP90AB3P Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HSP90AB3P Gene
Publications for HSP90AB3P Gene
- The HSP90 family of genes in the human genome: insights into their divergence and evolution. (PMID: 16269234) Chen B … Monteiro A (Genomics 2005) 2 3 4
- Assignment of an intron-containing human heat-shock protein gene (hsp90 beta, HSPCB) to chromosome 6 near TCTE1 (6p21) and two intronless pseudogenes to chromosomes 4 and 15 by polymerase chain reaction amplification from a panel of hybrid cell lines. (PMID: 8288256) Durkin AS … Nierman WC (Genomics 1993) 2 3
- PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. (PMID: 31091453) Shami Shah A … Baskin JM (Cell reports 2019) 3
- The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. (PMID: 29845934) Faust TB … Frankel AD (eLife 2018) 3
- Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved. (PMID: 30619736) Hussain T … Aldaz CM (Frontiers in oncology 2018) 3
Products for HSP90AB3P Gene
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- Custom Antibody Services
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- Custom Assay Services
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- Origene Custom Protein Services for HSP90AB3P
- Browse OriGene Inhibitory RNA Products For HSP90AB3P
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for HSP90AB3P
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HSP90AB3P
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- antibodies-online: Search results for available HSP90AB3P related products ranked by validation data
- antibodies-online: Search results for available HSP90AB3P related products ranked by validation data
- antibodies-online: Search results for available HSP90AB3P related products ranked by validation data
- Browse GeneCopoeia Cell Lines
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Sources for HSP90AB3P Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB