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HSF5 (Heat Shock Transcription Factor 5) is a Protein Coding gene. Diseases associated with HSF5 include Prediabetes Syndrome. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is HSF1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IBA | 21873635 |
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | NAS | 19274049 |
GO:0003677 | DNA binding | IEA | -- |
GO:0003700 | DNA-binding transcription factor activity | IBA | 21873635 |
GO:0043565 | sequence-specific DNA binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0034605 | cellular response to heat | IBA | 21873635 |
GO:0061408 | positive regulation of transcription from RNA polymerase II promoter in response to heat stress | IBA | 21873635 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | HSF5 33 32 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | HSF5 33 32 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | HSF5 33 32 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Hsf5 17 33 32 |
|
||
rat (Rattus norvegicus) |
Mammalia | Hsf5 32 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | HSF5 33 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | HSF5 33 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | LOC100858064 32 |
|
||
HSF5 33 |
|
OneToOne | |||
lizard (Anolis carolinensis) |
Reptilia | HSF5 33 |
|
OneToOne | |
zebrafish (Danio rerio) |
Actinopterygii | hsf5 33 |
|
OneToOne |
SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000020417 | -- | 58,463,544(-) | A/C | intron_variant | |
rs1000050063 | -- | 58,463,919(-) | A/T | intron_variant | |
rs1000073788 | -- | 58,459,921(-) | C/A | intron_variant | |
rs1000077964 | -- | 58,467,643(-) | T/C | intron_variant | |
rs1000129261 | -- | 58,452,671(-) | G/A | intron_variant |
Disorder | Aliases | PubMed IDs |
---|---|---|
prediabetes syndrome |
|
|