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HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008]
HSF2BP (Heat Shock Transcription Factor 2 Binding Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 21900206 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA | -- |
GO:0005829 | cytosol | HDA | 16780588 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006366 | transcription by RNA polymerase II | TAS | 9651507 |
GO:0007283 | spermatogenesis | TAS | 9651507 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | HSF2BP 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | HSF2BP 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | HSF2BP 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Hsf2bp 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Hsf2bp 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | HSF2BP 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | HSF2BP 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | HSF2BP 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | HSF2BP 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | hsf2bp 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | hsf2bp 30 31 |
|
OneToOne |
No disorders were found for HSF2BP Gene.