Aliases for HSF2 Gene
Aliases for HSF2 Gene
External Ids for HSF2 Gene
- HGNC: 5225
- Entrez Gene: 3298
- Ensembl: ENSG00000025156
- OMIM: 140581
- UniProtKB: Q03933
Previous GeneCards Identifiers for HSF2 Gene
- GC06P122491
- GC06P122678
- GC06P122702
- GC06P122703
- GC06P122762
- GC06P120297
Summaries for HSF2 Gene
-
The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
GeneCards Summary for HSF2 Gene
HSF2 (Heat Shock Transcription Factor 2) is a Protein Coding gene. Diseases associated with HSF2 include Acute Erythroid Leukemia. Among its related pathways are Proteolysis Putative SUMO-1 pathway. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is HSF1.
UniProtKB/Swiss-Prot for HSF2 Gene
-
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HSF2 Gene
Genomics for HSF2 Gene
GeneHancer (GH) Regulatory Elements for HSF2 Gene
Promoters and enhancers for HSF2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J122398 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 669.7 | +0.2 | 249 | 2.4 | HDGF PKNOX1 CLOCK ARID4B SIN3A DMAP1 YY1 POLR2B ZNF207 FOS | HSF2 PKIB ENSG00000279453 | |
| GH06J122470 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE dbSUPER | 18 | +71.8 | 71836 | 2.8 | PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 POLR2B | PKIB SERINC1 ENSG00000279114 HSF2 ENSG00000275339 | |
| GH06J122609 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE | 6.2 | +211.1 | 211144 | 2.6 | PKNOX1 FOXA2 ARID4B SIN3A FEZF1 YY1 GLIS2 ZNF213 NFKBIZ SP3 | PKIB SERINC1 HSF2 SMPDL3A PIR47029 ENSG00000272472 | |
| GH06J122408 | Enhancer | 0.6 | ENCODE | 19.5 | +9.6 | 9560 | 1.7 | ZBTB11 MAFG DPF2 ZNF316 GABPB1 KDM1A MAFK PRDM1 EMSY | HSF2 ENSG00000279453 | |
| GH06J122455 | Enhancer | 0.6 | dbSUPER | 18.1 | +60.9 | 60915 | 9.9 | SMARCE1 SOX13 KLF1 RFX1 DPF2 PLRG1 FOXA1 MITF ZNF217 CTBP1 | HSF2 PKIB ENSG00000275339 SERINC1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around HSF2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the HSF2 gene promoter:
-
- Sp1
- FOXO1a
- FOXO1
- RORalpha1
- HFH-1
- FOXL1
- PPAR-gamma2
- PPAR-gamma1
- CHOP-10
- C/EBPalpha
Regulatory Element Products
Genomic Locations for HSF2 Gene
Genomic Locations for HSF2 Gene
- chr6:122,399,546-122,433,119
- (GRCh38/hg38)
- Size:
- 33,574 bases
- Orientation:
- Plus strand
- chr6:122,720,691-122,754,264
- (GRCh37/hg19)
- Size:
- 33,574 bases
- Orientation:
- Plus strand
Genomic View for HSF2 Gene
Genes around HSF2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6q22.31 by Entrez Gene
- 6q22.31 by HGNC
- 6q22.31 by Ensembl
HSF2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HSF2 Gene
Proteins for HSF2 Gene
-
Protein details for HSF2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q03933-HSF2_HUMAN
- Recommended name:
- Heat shock factor protein 2
- Protein Accession:
- Q03933
- B4DGJ4
- Q0VAH9
- Q2M1K4
- Q9H445
Protein attributes for HSF2 Gene
- Size:
- 536 amino acids
- Molecular mass:
- 60348 Da
- Quaternary structure:
-
- DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer.
Protein Expression for HSF2 Gene
Post-translational modifications for HSF2 Gene
Other Protein References for HSF2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for HSF2 (HSF2)
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-
Abcam antibodies for HSF2
- Invitrogen Antibodies for HSF2 (AFLGC-HSF2)
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-
Santa Cruz Biotechnology (SCBT) Antibodies for HSF2
Protein Products
-
OriGene Purified Proteins for HSF2
- Search Origene for MassSpec and Protein Over-expression Lysates for HSF2
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- Search GeneTex for Proteins for HSF2
-
ProSci Proteins for HSF2
-
Abcam proteins for HSF2
Assay Products
- antibodies-online: Search results for available Hsf2 related products ranked by validation data
No data available for DME Specific Peptides for HSF2 Gene
Domains & Families for HSF2 Gene
Gene Families for HSF2 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Transcription factors
Protein Domains for HSF2 Gene
Suggested Antigen Peptide Sequences for HSF2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q03933- Family:
-
- Belongs to the HSF family.
Function for HSF2 Gene
Molecular function for HSF2 Gene
- UniProtKB/Swiss-Prot Function:
- DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Phenotypes From GWAS Catalog for HSF2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IDA | 10561509 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | -- |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | NAS | 19274049 |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | IDA | 10561509 |
| GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | IDA | 10561509 |
Phenotypes for HSF2 Gene
- MGI mutant phenotypes for HSF2:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for HSF2:
Animal Models for HSF2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
CRISPR Products
-
OriGene CRISPR knockouts for HSF2
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- Applied Biological Materials CRISPR for HSF2
-
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-
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- GenScript: Design CRISPR guide RNA sequences for HSF2
miRNA for HSF2 Gene
- miRTarBase miRNAs that target HSF2
-
- hsa-mir-18a-5p (MIRT005361)
- hsa-mir-26b-5p (MIRT029326)
- hsa-mir-24-3p (MIRT030504)
- hsa-let-7b-5p (MIRT052083)
- hsa-let-7a-5p (MIRT052530)
- hsa-mir-1324 (MIRT790104)
- hsa-mir-190a-3p (MIRT790142)
- hsa-mir-2115-3p (MIRT790178)
- hsa-mir-361-5p (MIRT790314)
- hsa-mir-3927-5p (MIRT790372)
- hsa-mir-4487 (MIRT790482)
- hsa-mir-454-5p (MIRT790520)
- hsa-mir-4633-3p (MIRT790525)
- hsa-mir-4802-5p (MIRT790653)
- hsa-mir-5011-5p (MIRT790680)
- hsa-mir-6500-5p (MIRT790851)
- hsa-mir-6514-5p (MIRT790862)
- hsa-mir-652-5p (MIRT790867)
- hsa-mir-6874-5p (MIRT791067)
- hsa-mir-8076 (MIRT791138)
Transcription Factor Targets for HSF2 Gene
miRNA Products
Inhibitory RNA Products
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Clone Products
- Sino Biological Human cDNA Clone for HSF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HSF2
- genomics-online: cdna clones - Search results for available Hsf2 gene related products
- orf clones - Search results for available Hsf2 gene related products
- Applied Biological Materials Clones for HSF2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for HSF2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology and HOMER Transcription for HSF2 Gene
Localization for HSF2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HSF2 Gene
- Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IBA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for HSF2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Proteolysis Putative SUMO-1 pathway | ||
Pathways by source for HSF2 Gene
1 GeneGo (Thomson Reuters) pathway for HSF2 Gene
Interacting Proteins for HSF2 Gene
Selected Interacting proteins:
Q03933-HSF2_HUMAN
ENSP00000357440
for HSF2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for HSF2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0006366 | transcription by RNA polymerase II | TAS | 1871106 |
| GO:0007283 | spermatogenesis | IEA | -- |
No data available for SIGNOR curated interactions for HSF2 Gene
Transcripts for HSF2 Gene
mRNA/cDNA for HSF2 Gene
- (3) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (164) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000368455 2549 bps (uc003pyu.3)
- ENST00000465214 642 bps (uc063rau.1)
- ENST00000452194 2643 bps (uc003pyv.2)
Unigene Clusters for HSF2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for HSF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HSF2
- genomics-online: gRNA clones - Search results for available Hsf2 gene related products
- Applied Biological Materials CRISPR for HSF2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HSF2
- GenScript: Design CRISPR guide RNA sequences for HSF2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HSF2
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HSF2
- genomics-online: shRNA clones - Search results for available Hsf2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for HSF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HSF2
- genomics-online: cdna clones - Search results for available Hsf2 gene related products
- orf clones - Search results for available Hsf2 gene related products
- Applied Biological Materials Clones for HSF2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for HSF2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for HSF2 Gene
This gene is overexpressed in Muscle - Skeletal (x4.4).
This gene is overexpressed in Bone marrow mesenchymal stem cell (68.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HSF2 Gene
NURSA nuclear receptor signaling pathways regulating expression of HSF2 Gene:
HSF2SOURCE GeneReport for Unigene cluster for HSF2 Gene:
Hs.158195Evidence on tissue expression from TISSUES for HSF2 Gene
- Nervous system(4.8)
Primer Products
-
OriGene qPCR primer pairs for HSF2
-
OriGene qPCR primer pairs and template standards for HSF2
- genomics-online: primer clones - Search results for available Hsf2 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HSF2 Gene
Orthologs for HSF2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HSF2 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HSF2 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | HSF2 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Hsf2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Hsf2 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HSF2 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | HSF2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HSF2 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | HSF2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hsf2 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hsf2 34 33 33 |
|
OneToOne | |
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7999 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Hsf 34 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | Y53C10A.12 35 |
|
|
|
| hsf-1 34 |
|
OneToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HSF1 34 |
|
OneToMany | |
| SKN7 36 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for HSF2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for HSF2 Gene
- ENSEMBL:
- Gene Tree for HSF2 (if available)
- TreeFam:
- Gene Tree for HSF2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HSF2: view image
Paralogs for HSF2 Gene
Variants for HSF2 Gene
| SNP ID | Clin | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs770437959 | uncertain-significance, Variant of unknown significance | 122,432,114(+) | G/A/T | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs1000001736 | -- | 122,401,317(+) | A/C | intron_variant | |
| rs1000101898 | -- | 122,408,492(+) | A/C | intron_variant | |
| rs1000228563 | -- | 122,426,992(+) | C/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000351585 | -- | 122,401,649(+) | T/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759467 | CNV | loss | 17122850 |
| nsv1161448 | CNV | duplication | 26073780 |
Residual Variation Intolerance Score:
14% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.82;
17.14% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HSF2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HSF2 Gene
Disorders for HSF2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acute erythroid leukemia |
|
Search HSF2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HSF2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for HSF2 Gene
Publications for HSF2 Gene
- Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans. (PMID: 1871106) Schuetz TJ … Kingston RE (Proceedings of the National Academy of Sciences of the United States of America 1991) 2 3 4 22 58
- Hydrophobic coiled-coil domains regulate the subcellular localization of human heat shock factor 2. (PMID: 8339932) Sheldon LA … Kingston RE (Genes & development 1993) 3 4 22 58
- PEST sequences mediate heat shock factor 2 turnover by interacting with the Cul3 subunit of the Cul3-RING ubiquitin ligase. (PMID: 19768582) Xing H … Sarge KD (Cell stress & chaperones 2010) 3 22 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Molecular basis for SUMOylation-dependent regulation of DNA binding activity of heat shock factor 2. (PMID: 19017645) Tateishi Y … Shirakawa M (The Journal of biological chemistry 2009) 3 22 58
Products for HSF2 Gene
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HSF2
- GeneCopoeia miRNA 3'UTR Target clone products for HSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HSF2
Sources for HSF2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt