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HSDL2 (Hydroxysteroid Dehydrogenase Like 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity. An important paralog of this gene is CBR1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0016491 | oxidoreductase activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005739 | mitochondrion | IBA,IDA | -- |
GO:0005777 | peroxisome | IEA,IDA | 19703561 |
GO:0016020 | membrane | HDA | 19946888 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008150 | biological_process | ND | -- |
GO:0055114 | oxidation-reduction process | IEA | -- |
ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||||||||||||
SP2: | - | - | - | ||||||||||||||||||||||||||||||
SP3: | - | - | |||||||||||||||||||||||||||||||
SP4: | - | - | - | - | |||||||||||||||||||||||||||||
SP5: | - | - | - | ||||||||||||||||||||||||||||||
SP6: |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | HSDL2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | HSDL2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | HSDL2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Hsdl2 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | HSDL2 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Mouse (Mus musculus) |
Mammalia | Hsdl2 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | HSDL2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | HSDL2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | hsdl2 30 |
|
||
Str.15284 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | MGC68498 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | hsdl2 30 31 |
|
OneToOne | |
wufb58f08 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP012513 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG5590 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | dhs-18 30 31 |
|
OneToMany | |
dhs-6 31 |
|
OneToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8410 31 |
|
OneToOne | |
Bread mold (Neurospora crassa) |
Ascomycetes | NCU00305 30 |
|
||
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.4883 30 |
|
SNP ID | Clinical significance and condition | Chr 09 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs3739696 | Benign: not provided | 112,454,041(+) |
A/G NM_032303.5(HSDL2):c.894A>G (p.Lys298=) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS | |
rs41280175 | Benign: not provided | 112,405,714(+) |
A/T NM_032303.5(HSDL2):c.272A>T (p.Lys91Ile) |
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT | |
rs77339398 | Benign: not provided | 112,409,029(+) |
T/C NM_032303.5(HSDL2):c.395+8T>C |
INTRON |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1231n67 | CNV | gain | 20364138 |
esv2678312 | CNV | deletion | 23128226 |
esv32838 | CNV | gain | 17666407 |
esv3621513 | CNV | loss | 21293372 |
esv3621514 | CNV | loss | 21293372 |
esv3621515 | CNV | loss | 21293372 |
nsv1047919 | CNV | loss | 25217958 |
nsv1051625 | CNV | loss | 25217958 |
nsv466487 | CNV | loss | 19166990 |
nsv511430 | CNV | loss | 21212237 |
nsv615196 | CNV | loss | 21841781 |
nsv6668 | CNV | insertion | 18451855 |
nsv6669 | CNV | insertion | 18451855 |
nsv825046 | CNV | gain | 20364138 |
No disorders were found for HSDL2 Gene.