Aliases for HSD17B7 Gene
External Ids for HSD17B7 Gene
Previous GeneCards Identifiers for HSD17B7 Gene
HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 126.96.36.199) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 188.8.131.520) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]
GeneCards Summary for HSD17B7 Gene
HSD17B7 (Hydroxysteroid 17-Beta Dehydrogenase 7) is a Protein Coding gene. Among its related pathways are Ovarian steroidogenesis and superpathway of steroid hormone biosynthesis. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and estradiol 17-beta-dehydrogenase activity. An important paralog of this gene is WWOX.
UniProtKB/Swiss-Prot Summary for HSD17B7 Gene
Responsible for the reduction of the keto group on the C-3 of sterols.