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Aliases for HRH1 Gene

Aliases for HRH1 Gene

  • Histamine Receptor H1 2 3 5
  • HH1R 3 4
  • H1R 3 4
  • Histamine Receptor, Subclass H1 3
  • Histamine H1 Receptor 3
  • HisH1 3
  • H1-R 3

External Ids for HRH1 Gene

Previous GeneCards Identifiers for HRH1 Gene

  • GC03P011223
  • GC03P011270
  • GC03P011271
  • GC03P011272

Summaries for HRH1 Gene

Entrez Gene Summary for HRH1 Gene

  • Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2015]

GeneCards Summary for HRH1 Gene

HRH1 (Histamine Receptor H1) is a Protein Coding gene. Diseases associated with HRH1 include Allergic Rhinitis and Rhinitis. Among its related pathways are Monoamine GPCRs and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and histamine binding. An important paralog of this gene is CHRM1.

UniProtKB/Swiss-Prot for HRH1 Gene

  • In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

Tocris Summary for HRH1 Gene

  • Histamine H1 receptors are Galphaq/11-protein-coupled receptors that mediate allergic responses. These receptors are expressed in a wide variety of tissues including the gastrointestinal tract, CNS, airway and vascular smooth muscle cells and endothelial cells.

Gene Wiki entry for HRH1 Gene

Additional gene information for HRH1 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HRH1 Gene

Genomics for HRH1 Gene

GeneHancer (GH) Regulatory Elements for HRH1 Gene

Promoters and enhancers for HRH1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I011154 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 553.4 +18.0 17988 2 RAD21 ZNF335 GLIS2 EGR1 ZNF143 RCOR1 DEK EGR2 ZNF654 SP3 HRH1 LOC105376951 SLC6A1 SLC6A11 VGLL4 LOC102723663
GH03I011223 Promoter/Enhancer 2 EPDnew Ensembl ENCODE dbSUPER 550.2 +88.3 88312 3.7 MXI1 ATF1 ZBTB21 JUN MAX SIN3A FOSL1 ZNF766 POLR2A FOSL2 HRH1 ATG7 CHCHD4P4 PIR59264
GH03I011134 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 550.8 -0.4 -374 3.7 PKNOX1 JUN MAX SIN3A RAD21 RFX5 FOSL1 ZFHX2 POLR2A NFYB HRH1 LOC101927467
GH03I011252 Promoter 0.7 EPDnew 550.1 +115.6 115587 0.1 SMARCE1 GATA3 HRH1 PIR61529 CHCHD4P4
GH03I011271 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 19.6 +136.3 136275 3.3 HDGF PKNOX1 SMAD1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 ATG7 HRH1 ENSG00000226621
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HRH1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the HRH1 gene promoter:

Genomic Locations for HRH1 Gene

Genomic Locations for HRH1 Gene
126,465 bases
Plus strand

Genomic View for HRH1 Gene

Genes around HRH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HRH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HRH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HRH1 Gene

Proteins for HRH1 Gene

  • Protein details for HRH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Histamine H1 receptor
    Protein Accession:
    Secondary Accessions:
    • A8K047
    • Q6P9E5

    Protein attributes for HRH1 Gene

    487 amino acids
    Molecular mass:
    55784 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for HRH1 Gene

neXtProt entry for HRH1 Gene

Post-translational modifications for HRH1 Gene

  • Phosphorylation at sites in the second and third cytoplasmic loops independently contribute to agonist-induced receptor downregulation.
  • Glycosylation at posLast=55 and posLast=1818
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for HRH1 Gene

Domains & Families for HRH1 Gene

Gene Families for HRH1 Gene

Human Protein Atlas (HPA):
  • FDA approved drug targets
  • G-protein coupled receptors
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for HRH1 Gene

Suggested Antigen Peptide Sequences for HRH1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with HRH1: view

Function for HRH1 Gene

Molecular function for HRH1 Gene

GENATLAS Biochemistry:
histamine H1 receptor,ubiquitous,G protein coupled receptor superfamily,activating adenylate cyclase,stimulating contraction on smooth muscle in the gut and bronchs and decreasing blood pressure
UniProtKB/Swiss-Prot Function:
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.

Phenotypes From GWAS Catalog for HRH1 Gene

Gene Ontology (GO) - Molecular Function for HRH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity TAS 7925364
GO:0004969 histamine receptor activity ISS --
genes like me logo Genes that share ontologies with HRH1: view
genes like me logo Genes that share phenotypes with HRH1: view

Animal Models for HRH1 Gene

MGI Knock Outs for HRH1:

Animal Model Products

Clone Products

  • Addgene plasmids for HRH1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HRH1 Gene

Localization for HRH1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HRH1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HRH1 gene
Compartment Confidence
plasma membrane 5
cytosol 5
nucleus 3
extracellular 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
  • Cytosol (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for HRH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane ISS,TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with HRH1: view

Pathways & Interactions for HRH1 Gene

genes like me logo Genes that share pathways with HRH1: view

SIGNOR curated interactions for HRH1 Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for HRH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006954 inflammatory response TAS 10818238
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS --
GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS 8280179
GO:0007613 memory IEA --
genes like me logo Genes that share ontologies with HRH1: view

Drugs & Compounds for HRH1 Gene

(296) Drugs for HRH1 Gene - From: DrugBank, ApexBio, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Cetirizine Approved Pharma Inverse agonist, Antagonist, Target, antagonist Antihistamine 140
Diphenhydramine Approved, Investigational Pharma Antagonist, Target, antagonist 255
Cyproheptadine Approved Pharma Antagonist, Target, antagonist 20
Risperidone Approved, Investigational Pharma Antagonist, Target, antagonist SR-2A inhibitor 498
Astemizole Approved, Withdrawn Pharma Pore Blocker, Target, antagonist 0

(34) Additional Compounds for HRH1 Gene - From: HMDB, Novoseek, and IUPHAR

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Promazine 5-sulfoxide

(5) Tocris Compounds for HRH1 Gene

Compound Action Cas Number
2-Pyridylethylamine dihydrochloride H1 receptor agonist 3343-39-3
Doxepin hydrochloride Highly potent H1 antagonist. Also binds to H4 receptor 1229-29-4
Histamine dihydrochloride Endogenous histamine receptor agonist 56-92-8
HTMT dimaleate H1 / H2 agonist 195867-54-0
Mepyramine maleate Selective H1 inverse agonist 59-33-6

(96) ApexBio Compounds for HRH1 Gene

Compound Action Cas Number
(R)-(-)-α-Methylhistamine dihydrobromide 868698-49-1
(S)-(+)-α-Methylhistamine dihydrobromide 75614-93-6
2-Pyridylethylamine dihydrochloride 3343-39-3
Alcaftadine 147084-10-4
Aminopotentidine 140873-26-3
Amthamine dihydrobromide 142457-00-9
Antazoline HCl 2508-72-7
Astemizole 68844-77-9
Azatadine 3964-81-6
Azatadine dimaleate 3978-86-7
Azelastine HCl 79307-93-0
Benztropine mesylate 132-17-2
Bepotastine Besilate 190786-44-8
Betahistine 2HCl 5579-84-0
Bilastine 202189-78-4
Brompheniramine hydrogen maleate 980-71-2
Buclizine HCl 129-74-8
Carcinine ditrifluoroacetate 56897-53-1
Cetirizine Antihistamine 83881-51-0
Cetirizine DiHCl H1 receptor inverse agonist 83881-52-1
Chlorpheniramine Maleate 113-92-8
Cimetidine H2 receptor antagonist 51481-61-9
Ciproxifan Histamine H3-receptor antagonist 184025-18-1
Ciproxifan maleate 184025-19-2
Clemastine Fumarate 14976-57-9
Clemizole H1 histamine receptor antagonist 442-52-4
Clemizole hydrochloride H1 histamine receptor antagonist 1163-36-6
Clobenpropit dihydrobromide 145231-35-2
Conessine 546-06-5
Cyclizine 2HCl 5897-18-7
Cyproheptadine hydrochloride 969-33-5
Decloxizine 3733-63-9
Decloxizine dihydrochloride 13073-96-6
Desloratadine 100643-71-8
Dimaprit dihydrochloride 23256-33-9
Diphenhydramine HCl 147-24-0
Doxylamine Succinate 562-10-7
DPPE fumarate 1185241-83-1
Ebastine 90729-43-4
Epinastine HCl 108929-04-0
Famotidine Histamine H2-receptor antagonist 76824-35-6
Fexofenadine HCl 153439-40-8
GT 2016 152241-24-2
Histamine 2HCl 56-92-8
Histamine Phosphate 51-74-1
HTMT dimaleate 195867-54-0
Hydroxyzine 68-88-2
Hydroxyzine 2HCl 2192-20-3
ICI 162,846 84545-30-2
Imetit dihydrobromide 32385-58-3
Immepip dihydrobromide 164391-47-3
Immethridine dihydrobromide 699020-93-4
Impentamine dihydrobromide 149629-70-9
Iodophenpropit dihydrobromide 145196-87-8
JNJ 10181457 dihydrochloride 544707-20-2
JNJ 10191584 maleate 869497-75-6
JNJ 5207852 dihydrochloride 398473-34-2
JNJ-7777120 Histamine H4 receptor antagonist 459168-41-3
Ketotifen Fumarate 34580-14-8
Lafutidine 118288-08-7
Latrepirdine Brain cell death inhibitor 97657-92-6
LED209 Highly selective for histidine sensor kinase QseC 245342-14-7
Levodropropizine Histamine receptor inhibitor,cough suppressant 99291-25-5
Lidocaine Anasthetic and class Ib antiarrhythmic agent 137-58-6
Loratadine Peripheral HH1R antagonist 79794-75-5
Meclizine 2HCl Histamine H1 receptor antagonist 1104-22-9
Mepyramine maleate 59-33-6
Methimepip dihydrobromide 817636-54-7
Mianserin 24219-97-4
Mianserin HCl 5-HT2 receptor antagonist 21535-47-7
Mizolastine 108612-45-9
Mizolastine dihydrochloride Histamine H1-receptor antagonist 1056596-82-7
Nizatidine 76963-41-2
Nα-Methylhistamine dihydrochloride 16503-22-3
Olopatadine HCl Histamine blocker 140462-76-6
Pemirolast potassium 100299-08-9
Pheniramine Maleate 132-20-7
Pitolisant Nonimidazole inverse agonist 362665-56-3
Pitolisant hydrochloride Nonimidazole inverse agonist 903576-44-3
Pitolisant oxalate Nonimidazole inverse agonist 362665-57-4
Promethazine HCl 58-33-3
Proxyfan oxalate 177708-09-7
Ranitidine Histamine H2-receptor antagonist 66357-59-3
ROS 234 dioxalate 184576-87-2
Roxatidine Acetate HCl 93793-83-0
Rupatadine Fumarate 182349-12-8
Serotonin HCl 153-98-0
Terfenadine Histamine H1-receptor antagonist 50679-08-8
Thioperamide 106243-16-7
Tiotidine 69014-14-8
trans-Triprolidine hydrochloride 550-70-9
Tripelennamine HCl H1-receptor antagonist 154-69-8
VUF 10460 1028327-66-3
VUF 5681 dihydrobromide 639089-06-8
VUF 8430 dihydrobromide 100130-32-3
Zolantidine dimaleate 104076-39-3
genes like me logo Genes that share compounds with HRH1: view

Drug Products

Transcripts for HRH1 Gene

Unigene Clusters for HRH1 Gene

Histamine receptor H1:
Representative Sequences:

Clone Products

  • Addgene plasmids for HRH1

Alternative Splicing Database (ASD) splice patterns (SP) for HRH1 Gene

No ASD Table

Relevant External Links for HRH1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HRH1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HRH1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for HRH1 Gene

This gene is overexpressed in Artery - Aorta (x4.1).

Protein differential expression in normal tissues from HIPED for HRH1 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for HRH1 Gene

Protein tissue co-expression partners for HRH1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of HRH1 Gene:


SOURCE GeneReport for Unigene cluster for HRH1 Gene:


Evidence on tissue expression from TISSUES for HRH1 Gene

  • Lung(4.5)
  • Eye(4.3)
  • Nervous system(2.7)
  • Blood(2)
  • Intestine(2)
  • Skin(2)
genes like me logo Genes that share expression patterns with HRH1: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HRH1 Gene

Orthologs for HRH1 Gene

This gene was present in the common ancestor of animals.

Orthologs for HRH1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia HRH1 33 34
  • 99.18 (n)
(Canis familiaris)
Mammalia HRH1 33 34
  • 86.65 (n)
(Bos Taurus)
Mammalia HRH1 33 34
  • 84.67 (n)
(Mus musculus)
Mammalia Hrh1 33 16 34
  • 80.73 (n)
(Rattus norvegicus)
Mammalia Hrh1 33
  • 80.3 (n)
(Ornithorhynchus anatinus)
Mammalia HRH1 34
  • 59 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 23 (a)
(Gallus gallus)
Aves HRH1 33 34
  • 54.88 (n)
(Anolis carolinensis)
Reptilia HRH1 34
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495566 33
  • 64.62 (n)
(Danio rerio)
Actinopterygii hrh1 33 34
  • 52.84 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG7918 34
  • 13 (a)
(Caenorhabditis elegans)
Secernentea gar-2 34
  • 15 (a)
gar-1 34
  • 14 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 23 (a)
-- 34
  • 23 (a)
Species where no ortholog for HRH1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HRH1 Gene

Gene Tree for HRH1 (if available)
Gene Tree for HRH1 (if available)

Paralogs for HRH1 Gene

Paralogs for HRH1 Gene

(2) SIMAP similar genes for HRH1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with HRH1: view

Variants for HRH1 Gene

Sequence variations from dbSNP and Humsavar for HRH1 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
VAR_035761 A colorectal cancer sample p.Asp385Glu
rs1000008364 -- 11,150,838(+) A/T genic_upstream_transcript_variant, intron_variant
rs1000032945 -- 11,228,773(+) G/A genic_upstream_transcript_variant, intron_variant
rs1000047411 -- 11,239,398(+) G/C genic_upstream_transcript_variant, intron_variant
rs1000064204 -- 11,190,765(+) C/T genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for HRH1 Gene

Variant ID Type Subtype PubMed ID
dgv4680n100 CNV loss 25217958
dgv762e201 CNV deletion 23290073
esv2151338 CNV deletion 18987734
esv2609663 CNV insertion 19546169
esv2724908 CNV deletion 23290073
esv2724909 CNV deletion 23290073
esv3331396 CNV insertion 20981092
esv3335879 CNV insertion 20981092
esv3404688 CNV insertion 20981092
esv3568612 CNV loss 25503493
esv3595288 CNV loss 21293372
esv3595289 CNV loss 21293372
esv3893662 CNV loss 25118596
esv4117 OTHER complex 18987735
nsv1073204 CNV deletion 25765185
nsv1076851 CNV insertion 25765185
nsv1121603 CNV deletion 24896259
nsv1123624 CNV deletion 24896259
nsv1140169 CNV insertion 24896259
nsv1143043 CNV tandem duplication 24896259
nsv1152949 CNV insertion 26484159
nsv436362 CNV deletion 17901297
nsv436869 CNV insertion 17901297

Variation tolerance for HRH1 Gene

Residual Variation Intolerance Score: 75.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.05; 37.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for HRH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HRH1 Gene

Disorders for HRH1 Gene

MalaCards: The human disease database

(14) MalaCards diseases for HRH1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
allergic rhinitis
  • alrh
  • runny nose
allergic conjunctivitis
  • conjunctivitis allergic
  • asthma, susceptibility to
- elite association - COSMIC cancer census association via MalaCards
Search HRH1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for HRH1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with HRH1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HRH1 Gene

Publications for HRH1 Gene

  1. Polymorphisms of high-affinity IgE receptor and histamine-related genes in patients with ASA-induced urticaria/angioedema. (PMID: 15953854) Choi JH … Park HS (Journal of Korean medical science 2005) 3 22 44 58
  2. Two threonine residues and two serine residues in the second and third intracellular loops are both involved in histamine H1 receptor downregulation. (PMID: 15328002) Horio S … Fukui H (FEBS letters 2004) 3 4 22 58
  3. Stable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the gene. (PMID: 7925364) Moguilevsky N … Bollen A (European journal of biochemistry 1994) 3 4 22 58
  4. Molecular cloning of the human histamine H1 receptor gene. (PMID: 8003029) Fukui H … Ito S (Biochemical and biophysical research communications 1994) 2 3 4 58
  5. Genomic cloning, heterologous expression and pharmacological characterization of a human histamine H1 receptor. (PMID: 8280179) De Backer MD … Luyten WH (Biochemical and biophysical research communications 1993) 3 4 22 58

Products for HRH1 Gene

  • Addgene plasmids for HRH1

Sources for HRH1 Gene

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