Aliases for HOXD9 Gene
External Ids for HOXD9 Gene
Previous HGNC Symbols for HOXD9 Gene
Previous GeneCards Identifiers for HOXD9 Gene
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXD9 Gene
HOXD9 (Homeobox D9) is a Protein Coding gene. Diseases associated with HOXD9 include Brachydactyly-Syndactyly Syndrome and Syndactyly, Type V. Among its related pathways are Chromatin Regulation / Acetylation. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is HOXC9.
UniProtKB/Swiss-Prot for HOXD9 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.