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This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in ... See more...
Aliases for HOXD10 Gene
Aliases for HOXD10 Gene
External Ids for HOXD10 Gene
- HGNC: 5133
- Entrez Gene: 3236
- Ensembl: ENSG00000128710
- OMIM: 142984
- UniProtKB: P28358
Previous HGNC Symbols for HOXD10 Gene
- HOX4
- HOX4D
Previous GeneCards Identifiers for HOXD10 Gene
- GC02P175034
- GC02P175642
- GC02P176945
- GC02P177184
- GC02P176807
- GC02P176689
- GC02P168858
- GC02P176973
Summaries for HOXD10 Gene
-
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXD10 Gene
HOXD10 (Homeobox D10) is a Protein Coding gene. Diseases associated with HOXD10 include Vertical Talus, Congenital and Congenital Vertical Talus, Unilateral. Among its related pathways are Proteoglycans in cancer and MicroRNAs in cancer. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and chromatin binding. An important paralog of this gene is HOXA10.
UniProtKB/Swiss-Prot Summary for HOXD10 Gene
-
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Additional gene information for HOXD10 Gene
- Monarch Initiative
- Search for HOXD10 at DataMed
- Search for HOXD10 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HOXD10 Gene
Genomics for HOXD10 Gene
GeneHancer (GH) Regulatory Elements for HOXD10 Gene
Promoters and enhancers for HOXD10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HOXD10 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HOXD10
- Top Transcription factor binding sites by QIAGEN in the HOXD10 gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for HOXD10 Gene
Genomic Locations for HOXD10 Gene
- chr2:176,108,790-176,119,942
- (GRCh38/hg38)
- Size:
- 11,153 bases
- Orientation:
- Plus strand
- chr2:176,973,518-176,984,670
- (GRCh37/hg19)
- Size:
- 11,153 bases
- Orientation:
- Plus strand
Genomic View for HOXD10 Gene
Genes around HOXD10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q31.1 by HGNC
- 2q31.1 by Entrez Gene
- 2q31.1 by Ensembl
HOXD10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HOXD10 Gene
Proteins for HOXD10 Gene
-
Protein details for HOXD10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P28358-HXD10_HUMAN
- Recommended name:
- Homeobox protein Hox-D10
- Protein Accession:
- P28358
- Q6NT10
Protein attributes for HOXD10 Gene
- Size:
- 340 amino acids
- Molecular mass:
- 38411 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for HOXD10 Gene
Other Protein References for HOXD10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences HOXD10 Antibody (LS-B14549) and HOXD10 Antibody (LS-B9199)
- Creative Diagnostics Anti-HOXD10 monoclonal antibody
- Novus Biologicals Antibodies for HOXD10
-
Abcam antibodies for HOXD10
- Invitrogen Antibodies for HOXD10 (AFLGC-HOXD10)
-
Boster Bio Antibodies for HOXD10
-
Santa Cruz Biotechnology (SCBT) Antibodies for HOXD10
Protein Products
- Creative Biomart Recombinant Human HOXD10
-
OriGene Purified Proteins for HOXD10
- Search Origene for MassSpec and Protein Over-expression Lysates for HOXD10
- Origene Custom Protein Services for HOXD10
-
Abcam proteins for HOXD10
Assay Products
-
RayBiotech
- Human and Mouse Phosphotyrosine EGFR ELISA
- Human and Mouse Phospho-EGFR (Y1068) ELISA
- Human Phospho-EGFR (S1070) ELISA
- Human and Mouse Phospho-EGFR (Y1068) and Total EGFR ELISA
- Human and Mouse Phospho-EGFR (Y992) ELISA
- Human Phospho-EGFR (Y1045) ELISA
- Human and Mouse Phospho-EGFR (Y1086) ELISA
- Human and Mouse Phospho-EGFR (Y1086) and Total EGFR ELISA
- Human Phospho-EGFR (S1070) and Total EGFR ELISA
- Human and Mouse Phospho-EGFR (Y992) and Total EGFR ELISA
- Human Phospho-EGFR (Y1045) and Total EGFR ELISA
No data available for DME Specific Peptides for HOXD10 Gene
Domains & Families for HOXD10 Gene
Gene Families for HOXD10 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for HOXD10 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HOXD10 Gene
- GenScript: Design optimal peptide antigens:
-
- Homeobox protein Hox-4E (HXD10_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P28358- Family:
-
- Belongs to the Abd-B homeobox family.
Function for HOXD10 Gene
Molecular function for HOXD10 Gene
- UniProtKB/Swiss-Prot Function:
- Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
- GENATLAS Biochemistry:
- homeo box D10(4D),homologous to mouse Hox-4.5
Phenotypes From GWAS Catalog for HOXD10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IEA | -- |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | NAS | 19274049 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003682 | chromatin binding | IEA | -- |
Phenotypes for HOXD10 Gene
- MGI mutant phenotypes for HOXD10:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for HOXD10:
Animal Models for HOXD10 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HOXD10 - Select products 50% OFF >
- * HOXD10 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
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- Overview of 120 available HOXD10 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for HOXD10
miRNA for HOXD10 Gene
- miRTarBase miRNAs that target HOXD10
miRNA Products
Inhibitory RNA Products
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- Overview of 120 available HOXD10 gene related products
Clone Products
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- Sino Biological Human cDNA Clone for HOXD10
- Addgene plasmids for HOXD10
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Cell Line Products
-
Horizon Cell Lines for HOXD10
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for HOXD10 Gene
Localization for HOXD10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HOXD10 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytoplasmic bodies (2)
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0036464 | cytoplasmic ribonucleoprotein granule | IDA | -- |
Pathways & Interactions for HOXD10 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | MicroRNAs in cancer | ||
| 2 | Proteoglycans in cancer | ||
Pathways by source for HOXD10 Gene
2 KEGG pathways for HOXD10 Gene
Interacting Proteins for HOXD10 Gene
GPS-Prot Interaction Network for HOXD10
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001501 | skeletal system development | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0007338 | single fertilization | IEA | -- |
| GO:0007519 | skeletal muscle tissue development | IEA | -- |
Drugs & Compounds for HOXD10 Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human HOXD10
Transcripts for HOXD10 Gene
mRNA/cDNA for HOXD10 Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000249501 1989 bps (ENST00000249501.4)
- ENST00000490088 1010 bps (ENST00000490088.2)
- ENST00000549469 906 bps (ENST00000549469.1)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HOXD10 - Select products 50% OFF >
- * HOXD10 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HOXD10
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HOXD10
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- Overview of 120 available HOXD10 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for HOXD10
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HOXD10
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HOXD10
- genomics-online: shRNA clones - Search for available HOXD10 shRNA products
- Overview of 120 available HOXD10 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for HOXD10 - Select products 50% OFF >
- * HOXD10 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HOXD10
- Addgene plasmids for HOXD10
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HOXD10
Relevant External Links for HOXD10 Gene
- GeneLoc Exon Structure for
- HOXD10
Expression for HOXD10 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Mesenchymal Stem Cells (Uncategorized)
-
Limb (Muscoskeletal System)
- Progress Zone Cells Limb Bud
- Zone Of Polarizing Activity Cells Limb Bud
- Prechondrocytic Mesenchymal Cells Stylopod
- Limb Bud Mesenchyme Cells Limb Bud
- Umbilical Cord (Extraembryonic Tissues)
-
Kidney (Urinary System)
- Metanephric Mesenchyme Cells Metanephric Mesenchyme
- Renal Vesicle
- Metanephros
-
Bone (Muscoskeletal System)
- Sclerotome Cells Sacral Mesenchymal Sclerotome
- Progress Zone Cells Limb Bud
- Prechondrocytic Mesenchymal Cells Stylopod
-
Cartilage (Muscoskeletal System)
- Sclerotome Cells Sacral Mesenchymal Sclerotome
- Progress Zone Cells Limb Bud
- Prechondrocytic Mesenchymal Cells Stylopod
-
Mesoderm (Gastrulation Derivatives)
- Zone Of Polarizing Activity Cells Limb Bud
- Limb Bud Mesenchyme Cells Limb Bud
- Placenta (Extraembryonic Tissues)
- Blood (Hematopoietic System)
-
Somite (Muscoskeletal System)
- Sclerotome Cells Sacral Mesenchymal Sclerotome
-
Tendon amp Ligament
- Sclerotome Cells Sacral Mesenchymal Sclerotome
-
Spinal Cord (Nervous System)
- Lateral Motor Neurons Lumbar Lateral Motor Column
-
Neurons
- Lateral Motor Neurons Lumbar Lateral Motor Column
-
Ovary (Reproductive System)
- Ovarian Mesenchymal Stroma Cells Ovary Interstitium
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Dermis (Integumentary System)
- Dermal Fibroblasts Dorsal Dermis
-
Fibroblasts
- Dermal Fibroblasts Dorsal Dermis
- Brain (Nervous System)
- Neural Tube (Nervous System)
- Trophoblast (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for HOXD10 Gene
This gene is overexpressed in Uterus (x13.3), Vagina (x7.8), Colon - Sigmoid (x6.9), Cervix - Ectocervix (x5.5), Kidney - Cortex (x4.9), and Prostate (x4.8).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HOXD10
SOURCE GeneReport for Unigene cluster for HOXD10 Gene:
Hs.123070mRNA Expression by UniProt/SwissProt for HOXD10 Gene:
P28358-HXD10_HUMAN
Tissue specificity:
Strongly expressed in the adult male and female urogenital tracts.
Evidence on tissue expression from TISSUES for HOXD10 Gene
- Intestine(4.2)
- Nervous system(4.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for HOXD10 Gene
Germ Layers:
- mesoderm
Systems:
- skeletal muscle
- skeleton
Regions:
Limb:
- ankle
- digit
- elbow
- finger
- foot
- hand
- hip
- knee
- lower limb
- shoulder
- toe
- upper limb
- wrist
Primer Products
-
OriGene qPCR primer pairs for HOXD10
-
OriGene qPCR primer pairs and template standards for HOXD10
- genomics-online: primer clones - Search for available HOXD10 Primer products
- Overview of 120 available HOXD10 gene related products
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for HOXD10 Gene
Orthologs for HOXD10 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HOXD10 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HOXD11 30 |
|
||
| HOXD10 31 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | HOXD10 31 30 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Hoxd10 30 |
|
||
| mouse (Mus musculus) |
Mammalia | Hoxd10 17 31 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | HOXD10 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HOXD10 31 30 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | HOXD10 31 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hoxd10 30 |
|
||
| Str.2493 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC68611 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | hoxd10a 31 30 30 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for HOXD10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for HOXD10 Gene
- ENSEMBL:
- Gene Tree for HOXD10 (if available)
- TreeFam:
- Gene Tree for HOXD10 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HOXD10: view image
Paralogs for HOXD10 Gene
Paralogs for HOXD10 Gene
- HOXA10 5
- HOXC10 5
- HOXD9 5
- HOXC9 5
- HOXB9 5
- HOXA11 5
- HOXC11 5
- HOXD11 5
- HOXC12 5
- HOXD12 5
- HOXD13 5
- HOXA13 5
- PDX1 5
- HOXA3 5
- HOXB8 5
- HOXC8 5
- HOXB5 5
- HOXD8 5
- HOXC13 5
- HOXB1 5
- HOXA1 5
- HOXB4 5
- HOXC4 5
- HOXD3 5
- HOXC6 5
- HOXB3 5
- HOXA2 5
- HOXD4 5
- HOXA4 5
- HOXD1 5
- HOXA7 5
- HOXB2 5
- HOXA5 5
- TLX3 5
- TLX1 5
- HOXA6 5
- HOXB6 5
- HOXB7 5
- HOXC5 5
- HOXB13 5
- GSX2 5
- TLX2 5
- ENSG00000273049 5
Variants for HOXD10 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HOXD10 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 714132 | Benign: not provided | 176,118,976(+) | A/C | SYNONYMOUS_VARIANT | |
| 775790 | Benign: not provided | 176,118,951(+) | T/C | INTRON_VARIANT | |
| 808888 | Uncertain Significance: not provided | 176,117,125(+) | G/A | MISSENSE_VARIANT | |
| 811018 | Benign: not specified | 176,117,597(+) | G/A | INTRON_VARIANT | |
| 811668 | Likely Benign: not specified | 176,117,262(+) | C/T | SYNONYMOUS_VARIANT |
Residual Variation Intolerance Score:
42.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.29;
25.66% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HOXD10 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HOXD10 Gene
Disorders for HOXD10 Gene
(11) MalaCards diseases for HOXD10 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| vertical talus, congenital |
|
|
| congenital vertical talus, unilateral |
|
|
| congenital vertical talus, bilateral |
|
|
| syndactyly, type v |
|
|
| charcot-marie-tooth disease |
|
Search HOXD10 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
HXD10_HUMAN- Vertical talus, congenital (CVT) [MIM:192950]: A rare malformation characterized by vertical orientation of the talus with a rigid dorsal dislocation of the navicular, equinus deformity of the calcaneus, abduction deformity of the forefoot, and contracture of the soft tissues of the hind- and mid-foot. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity with familial occurrence. {ECO:0000269 PubMed:15146389}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for HOXD10
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for HOXD10 Gene
Publications for HOXD10 Gene
- A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. (PMID: 15146389) Shrimpton AE … Hootnick DR (American journal of human genetics 2004) 3 4 23 54
- HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities. (PMID: 1756725) Zappavigna V … Duboule D (The EMBO journal 1991) 3 4 23 54
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PMID: 19453261) Yerges LM … MrOS Research Group (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009) 3 41 54
- MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions. (PMID: 18922890) Reddy SD … Kumar R (Cancer research 2008) 3 23 54
- Absence of HOXD10 mutations in idiopathic clubfoot and sporadic vertical talus. (PMID: 17417092) Gurnett CA … Dobbs MB (Clinical orthopaedics and related research 2007) 3 41 54
ExternalLinks
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- VectorBuilder Viral vectors for HOXD10 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HOXD10 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HOXD10 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HOXD10
- Addgene plasmids for HOXD10
- antibodies-online: Show 75 available HOXD10 Antibodies ranked by validation data
- Compare Top HOXD10 Antibodies
- antibodies-online: Search results for available HOXD10 related products ranked by validation data
- antibodies-online: Show 12 available HOXD10 Proteins ranked by validation data
- Compare Top HOXD10 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for HOXD10
- Search Santa Cruz Biotechnology (SCBT) for HOXD10 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HOXD10
- Horizon Cell Lines for HOXD10
- genomics-online: cdna clones - Search for available HOXD10 CDNA products
- Overview of 120 available HOXD10 gene related products
- orf clones - Search for available HOXD10 ORF products
- Overview of 120 available HOXD10 gene related products
- genomics-online: gRNA clones - Search for available HOXD10 gRNA products
- Overview of 120 available HOXD10 gene related products
- genomics-online: primer clones - Search for available HOXD10 Primer products
- Overview of 120 available HOXD10 gene related products
- genomics-online: shRNA clones - Search for available HOXD10 shRNA products
- Overview of 120 available HOXD10 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HOXD10
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HOXD10
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HOXD10
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HOXD10
- Boster Bio Antibodies for HOXD10
- Browse Boster Bio ELISA Kits
Sources for HOXD10 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource
- (179) Signalway Antibody