Aliases for HOXC8 Gene
External Ids for HOXC8 Gene
Previous HGNC Symbols for HOXC8 Gene
Previous GeneCards Identifiers for HOXC8 Gene
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXC8 Gene
HOXC8 (Homeobox C8) is a Protein Coding gene. Among its related pathways are Differentiation of white and brown adipocyte. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is HOXB8.
UniProtKB/Swiss-Prot for HOXC8 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.