Aliases for HOXB-AS3 Gene

Data sources for HOXB-AS3 Gene:

RNA type for HOXB-AS3 Gene

lncRNA

Aliases for HOXB-AS3 Gene

External Ids for HOXB-AS3 Gene

Previous GeneCards Identifiers for HOXB-AS3 Gene

  • GC17P046667
  • GC17P046626

Summaries for HOXB-AS3 Gene

GeneCards Summary for HOXB-AS3 Gene

HOXB-AS3 (HOXB Cluster Antisense RNA 3) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with HOXB-AS3 include Colorectal Cancer.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HOXB-AS3 Gene

Genomics for HOXB-AS3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for HOXB-AS3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HOXB-AS3 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for HOXB-AS3 Gene

Latest Assembly
chr17:48,549,629-48,606,414
(GRCh38/hg38)
Size:
56,786 bases
Orientation:
Plus strand

Previous Assembly
chr17:46,667,782-46,683,776
(GRCh37/hg19 by Entrez Gene)
Size:
15,995 bases
Orientation:
Plus strand

chr17:46,626,992-46,683,776
(GRCh37/hg19 by Ensembl)
Size:
56,785 bases
Orientation:
Plus strand

Genomic View for HOXB-AS3 Gene

Genes around HOXB-AS3 on UCSC Golden Path with GeneCards custom track
HOXB-AS3 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
HOXB-AS3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HOXB-AS3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HOXB-AS3 Gene

Proteins for HOXB-AS3 Gene

Post-translational modifications for HOXB-AS3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HOXB-AS3 Gene

Domains & Families for HOXB-AS3 Gene

Gene Families for HOXB-AS3 Gene

genes like me logo Genes that share domains with HOXB-AS3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for HOXB-AS3 Gene

Function for HOXB-AS3 Gene

Phenotypes From GWAS Catalog for HOXB-AS3 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HOXB-AS3 Gene

Localization for HOXB-AS3 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HOXB-AS3 gene
Compartment Confidence
extracellular 1
nucleus 1
endoplasmic reticulum 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HOXB-AS3 Gene

Pathways & Interactions for HOXB-AS3 Gene

PathCards logo

SuperPathways for HOXB-AS3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for HOXB-AS3 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for HOXB-AS3 Gene

Drugs & Compounds for HOXB-AS3 Gene

No Compound Related Data Available

Transcripts for HOXB-AS3 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for HOXB-AS3 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000380DF0_9606 lncRNA 747 4

Ensembl: ENST00000477144 (view in UCSC) ,

LncBook: HSALNT0241979,

LNCipedia: HOXB-AS3:37,

NONCODE: NONHSAT054444.2,

URS000017907F_9606 lncRNA 744 4

Ensembl: ENST00000474040 (view in UCSC) ,

LncBook: HSALNT0241967,

LNCipedia: HOXB-AS3:27,

NONCODE: NONHSAT054432.2,

URS00000671A3_9606 lncRNA 438 4

Ensembl: ENST00000465846 (view in UCSC) ,

LncBook: HSALNT0241947,

LNCipedia: HOXB-AS3:21,

NONCODE: NONHSAT054408.2,

URS0000577CFF_9606 lncRNA 728 3

Ensembl: ENST00000460041 (view in UCSC) ,

LNCipedia: HOXB-AS3:35,

NONCODE: NONHSAT054442.2,

URS0000200F0A_9606 lncRNA 543 3

Ensembl: ENST00000476204 (view in UCSC) ,

LNCipedia: HOXB-AS3:22,

NONCODE: NONHSAT054431.2,

HOXB-AS3 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for HOXB-AS3 Gene

11 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for HOXB-AS3 Gene

No ASD Table

Relevant External Links for HOXB-AS3 Gene

GeneLoc Exon Structure for
HOXB-AS3

Expression for HOXB-AS3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HOXB-AS3 Gene

mRNA differential expression in normal tissues according to GTEx for HOXB-AS3 Gene

This gene is overexpressed in Colon - Sigmoid (x11.0), Kidney - Cortex (x8.6), and Colon - Transverse (x6.0).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HOXB-AS3

SOURCE GeneReport for Unigene cluster for HOXB-AS3 Gene:

Hs.660088
genes like me logo Genes that share expression patterns with HOXB-AS3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HOXB-AS3 Gene

Orthologs for HOXB-AS3 Gene

Evolution for HOXB-AS3 Gene

ENSEMBL:
Gene Tree for HOXB-AS3 (if available)
TreeFam:
Gene Tree for HOXB-AS3 (if available)
Alliance of Genome Resources:
Additional Orthologs for HOXB-AS3

No data available for Orthologs for HOXB-AS3 Gene

Paralogs for HOXB-AS3 Gene

No data available for Paralogs for HOXB-AS3 Gene

Variants for HOXB-AS3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HOXB-AS3 Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
rs756724993 Uncertain Significance: not specified 48,596,652(+) C/T
NM_018952.5(HOXB6):c.436G>A (p.Gly146Ser)
MISSENSE
rs762346893 Uncertain Significance: not specified 48,598,060(+) C/T
NM_018952.5(HOXB6):c.91G>A (p.Gly31Ser)
MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for HOXB-AS3 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for HOXB-AS3 Gene

Variant ID Type Subtype PubMed ID
dgv369n27 CNV loss 19166990
dgv5676n54 CNV loss 21841781
esv2758694 CNV gain 17122850
nsv833469 CNV loss 17160897
nsv833471 CNV gain 17160897

Additional Variant Information for HOXB-AS3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HOXB-AS3
Leiden Open Variation Database (LOVD)
HOXB-AS3

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HOXB-AS3 Gene

Disorders for HOXB-AS3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for HOXB-AS3 Gene - From: LNC and COP

Disorder Aliases PubMed IDs
colorectal cancer
  • crc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for HOXB-AS3

genes like me logo Genes that share disorders with HOXB-AS3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HOXB-AS3 Gene

Publications for HOXB-AS3 Gene

  1. Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome. (PMID: 31234830) Huang HH … Chen RH (BMC cancer 2019) 2 3
  2. A Peptide Encoded by a Putative lncRNA HOXB-AS3 Suppresses Colon Cancer Growth. (PMID: 28985503) Huang JZ … Yan GR (Molecular cell 2017) 3 72
  3. LncRNA HOXB-AS3 promotes growth, invasion and migration of epithelial ovarian cancer by altering glycolysis. (PMID: 33148416) Xu S … Wang Y (Life sciences 2021) 3
  4. lncRNA HOXB-AS3 exacerbates proliferation, migration, and invasion of lung cancer via activating the PI3K-AKT pathway. (PMID: 32039488) Jiang W … Wang W (Journal of cellular physiology 2020) 3
  5. The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia. (PMID: 31767858) Papaioannou D … Garzon R (Nature communications 2019) 3

Products for HOXB-AS3 Gene

Sources for HOXB-AS3 Gene