Aliases for HOXA3 Gene
External Ids for HOXA3 Gene
Previous HGNC Symbols for HOXA3 Gene
Previous GeneCards Identifiers for HOXA3 Gene
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for HOXA3 Gene
HOXA3 (Homeobox A3) is a Protein Coding gene. Diseases associated with HOXA3 include Penile Cancer and Penile Benign Neoplasm. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Developmental Biology. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and HMG box domain binding. An important paralog of this gene is HOXB3.
UniProtKB/Swiss-Prot Summary for HOXA3 Gene
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.