Free for academic non-profit institutions. Other users need a Commercial license

Aliases for HOXA11-AS Gene

Subcategory (RNA class) for HOXA11-AS Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for HOXA11-AS Gene

  • HOXA11 Antisense RNA 2 3 5
  • HOXA Cluster Antisense RNA 5 (Non-Protein Coding) 2 3
  • HOXA11 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Homeobox A11 Antisense 2 3
  • Homeo Box A11, Opposite Strand Transcript 3
  • HOXA11 Antisense RNA (Non-Protein Coding) 2
  • Non-Protein Coding RNA 76 2
  • HOXA11-AS1 3
  • NCRNA00076 3
  • HOXA-AS5 3
  • HOXA11AS 3
  • HOXA11S 3

External Ids for HOXA11-AS Gene

Previous HGNC Symbols for HOXA11-AS Gene

  • HOXA11AS

Previous GeneCards Identifiers for HOXA11-AS Gene

  • GC07P027230

Summaries for HOXA11-AS Gene

Entrez Gene Summary for HOXA11-AS Gene

  • This gene produces a long non-coding RNA in antisense to transcription of the homeobox A11 gene. This transcript may associate with chromatin factors such as Polycomb repressive complex and act as a sponge for microRNAs, thereby participating in the regulation of expression of target genes. High levels of this transcript may be associated with tumor progression. [provided by RefSeq, Dec 2017]

GeneCards Summary for HOXA11-AS Gene

HOXA11-AS (HOXA11 Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with HOXA11-AS include Cervix Carcinoma and Melanoma, Uveal.

Additional gene information for HOXA11-AS Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HOXA11-AS Gene

Genomics for HOXA11-AS Gene

GeneHancer (GH) Regulatory Elements for HOXA11-AS Gene

Promoters and enhancers for HOXA11-AS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J027181 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 677.7 -0.2 -199 5.1 HDGF PKNOX1 FEZF1 ZNF2 YY1 GLIS2 ELK1 KLF7 REST SMARCB1 HOXA11-AS ENSG00000273961 ENSG00000276496 ENSG00000278334 GC07P027266 GC07P027267 HOXA11 HOXA10-AS HOTAIRM1 HOXA10
GH07J027095 Promoter/Enhancer 3.4 VISTA UCNEbase EPDnew FANTOM5 Ensembl ENCODE dbSUPER 15.8 -46.3 -46323 86.3 MLX FEZF1 DMAP1 YY1 ZNF213 ZNF143 SP3 NFYC SSRP1 ZNF610 HOXA2 HOXA9 HOXA10 HOXA1 HOXA3 HOXA6 HOXA4 HOXA5 HOXA7 HNRNPA2B1
GH07J027920 Enhancer 1 Ensembl ENCODE 10.7 +736.8 736797 0.6 MZF1 SIN3A BMI1 FEZF1 ZNF2 RAD21 RFX5 ZNF335 ZNF213 ZSCAN5C ENSG00000253508 HOTTIP HOXA13 HOXA11 HOXA11-AS HOXA10 HOXA9 ENSG00000253308 EVX1 EVX1-AS
GH07J028082 Enhancer 1.1 FANTOM5 Ensembl ENCODE 9.7 +899.2 899165 2.6 FOXA2 RXRA CEBPB REST EP300 RFX5 YY1 SP1 JUND ATF3 JAZF1 JAZF1-AS1 HOXA11 HOXA11-AS HOXA10 HOXA9 HOXA13 ENSG00000253508 HOTTIP EVX1-AS
GH07J028018 Enhancer 1 Ensembl ENCODE 10.3 +835.2 835235 2.2 RB1 SIN3A ZNF2 RAD21 RFX5 ZNF143 RCOR1 RUNX3 CREM DEK ENSG00000253508 HOXA13 HOTTIP HOXA10 HOXA11-AS HOXA11 HOXA9 PIR54187 PIR39851 JAZF1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HOXA11-AS on UCSC Golden Path with GeneCards custom track

Genomic Locations for HOXA11-AS Gene

Genomic Locations for HOXA11-AS Gene
chr7:27,184,518-27,189,293
(GRCh38/hg38)
Size:
4,776 bases
Orientation:
Plus strand
chr7:27,224,137-27,228,912
(GRCh37/hg19)
Size:
4,776 bases
Orientation:
Plus strand

Genomic View for HOXA11-AS Gene

Genes around HOXA11-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HOXA11-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HOXA11-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HOXA11-AS Gene

Proteins for HOXA11-AS Gene

Post-translational modifications for HOXA11-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for HOXA11-AS Gene

Domains & Families for HOXA11-AS Gene

Gene Families for HOXA11-AS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HOXA11-AS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HOXA11-AS Gene

Function for HOXA11-AS Gene

Phenotypes From GWAS Catalog for HOXA11-AS Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HOXA11-AS Gene

Localization for HOXA11-AS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HOXA11-AS Gene

Pathways & Interactions for HOXA11-AS Gene

SuperPathways for HOXA11-AS Gene

No Data Available

Interacting Proteins for HOXA11-AS Gene

Gene Ontology (GO) - Biological Process for HOXA11-AS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HOXA11-AS Gene

Drugs & Compounds for HOXA11-AS Gene

No Compound Related Data Available

Transcripts for HOXA11-AS Gene

mRNA/cDNA for HOXA11-AS Gene

(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(6) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for HOXA11-AS Gene

No ASD Table

Relevant External Links for HOXA11-AS Gene

GeneLoc Exon Structure for
HOXA11-AS
ECgene alternative splicing isoforms for
HOXA11-AS

Expression for HOXA11-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HOXA11-AS Gene

mRNA differential expression in normal tissues according to GTEx for HOXA11-AS Gene

This gene is overexpressed in Prostate (x8.0), Colon - Transverse (x7.2), Uterus (x6.3), Colon - Sigmoid (x6.3), Cervix - Endocervix (x5.8), and Cervix - Ectocervix (x5.3).
genes like me logo Genes that share expression patterns with HOXA11-AS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HOXA11-AS Gene

Orthologs for HOXA11-AS Gene

Evolution for HOXA11-AS Gene

ENSEMBL:
Gene Tree for HOXA11-AS (if available)
TreeFam:
Gene Tree for HOXA11-AS (if available)

No data available for Orthologs for HOXA11-AS Gene

Paralogs for HOXA11-AS Gene

No data available for Paralogs for HOXA11-AS Gene

Variants for HOXA11-AS Gene

Sequence variations from dbSNP and Humsavar for HOXA11-AS Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1085307723 uncertain-significance, not specified 27,184,520(+) C/T upstream_transcript_variant
rs1000053708 -- 27,188,643(+) A/T non_coding_transcript_variant
rs1000416261 -- 27,188,780(+) G/A non_coding_transcript_variant
rs1000472153 -- 27,188,484(+) A/C intron_variant
rs1000801577 -- 27,187,286(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for HOXA11-AS Gene

Variant ID Type Subtype PubMed ID
dgv1094n67 CNV gain 20364138
nsv5675 CNV insertion 18451855
nsv606465 CNV loss 21841781
nsv606468 CNV loss 21841781
nsv606469 CNV loss 21841781
nsv7393 OTHER inversion 18451855
nsv824042 CNV gain 20364138

Additional Variant Information for HOXA11-AS Gene

Human Gene Mutation Database (HGMD)
HOXA11-AS
SNPedia medical, phenotypic, and genealogical associations of SNPs for
HOXA11-AS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HOXA11-AS Gene

Disorders for HOXA11-AS Gene

MalaCards: The human disease database

(13) MalaCards diseases for HOXA11-AS Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
cervix carcinoma
  • cancer of cervix
melanoma, uveal
  • uveal melanoma
cervical cancer
  • cervical cancer, somatic
glioma
malignant glioma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for HOXA11-AS

genes like me logo Genes that share disorders with HOXA11-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HOXA11-AS Gene

Publications for HOXA11-AS Gene

  1. HOXA11 silencing and endogenous HOXA11 antisense ribonucleic acid in the uterine endometrium. (PMID: 12050232) Chau YM … Taylor HS (The Journal of clinical endocrinology and metabolism 2002) 2 3 58
  2. Evolutionary conservation and tissue-specific processing of Hoxa 11 antisense transcripts. (PMID: 9745033) Potter SS … Branford WW (Mammalian genome : official journal of the International Mammalian Genome Society 1998) 2 3 58
  3. Aberrant Expression of lncRNA ( HOXA11-AS1) and Homeobox A ( HOXA9, HOXA10, HOXA11, and HOXA13) Genes in Infertile Women With Endometriosis. (PMID: 29017417) Wang M … Yan W (Reproductive sciences (Thousand Oaks, Calif.) 2018) 3 58
  4. Effect of lncRNA HOXA11-AS1 on adipocyte differentiation in human adipose-derived stem cells. (PMID: 29217197) Nuermaimaiti N … Guan Y (Biochemical and biophysical research communications 2018) 3 58
  5. Underexpression of HOXA11 Is Associated with Treatment Resistance and Poor Prognosis in Glioblastoma. (PMID: 27456940) Se YB … Park CK (Cancer research and treatment : official journal of Korean Cancer Association 2017) 3 58

Products for HOXA11-AS Gene

Sources for HOXA11-AS Gene

Content
Loading form....