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Aliases for HOXA-AS2 Gene

Subcategory (RNA class) for HOXA-AS2 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HOXA-AS2 Gene

  • HOXA Cluster Antisense RNA 2 2 3 5
  • HOXA Cluster Antisense RNA 2 (Non-Protein Coding) 2 3
  • HOXA3as 3

External Ids for HOXA-AS2 Gene

Previous GeneCards Identifiers for HOXA-AS2 Gene

  • GC07P027151

Summaries for HOXA-AS2 Gene

Entrez Gene Summary for HOXA-AS2 Gene

  • This gene produces a long non-coding RNA that promotes cell proliferation. This transcript may interact with enhancer of zeste homolog 2 Polycomb repressive complex to repress gene expression. [provided by RefSeq, Dec 2017]

GeneCards Summary for HOXA-AS2 Gene

HOXA-AS2 (HOXA Cluster Antisense RNA 2) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for HOXA-AS2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HOXA-AS2 Gene

Genomics for HOXA-AS2 Gene

GeneHancer (GH) Regulatory Elements for HOXA-AS2 Gene

Promoters and enhancers for HOXA-AS2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I027095 Promoter/Enhancer 3.4 VISTA UCNEbase EPDnew FANTOM5 Ensembl ENCODE dbSUPER 21.2 +30.4 30418 86.3 MLX FEZF1 DMAP1 YY1 ZNF213 ZNF143 SP3 NFYC SSRP1 ZNF610 HOXA2 HOXA9 HOXA10 HOXA1 HOXA3 HOXA6 HOXA4 HOXA5 HOXA7 HNRNPA2B1
GH07I026862 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.6 -243.7 -243663 3.1 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 SKAP2 HOTAIRM1 HNRNPA2B1 HOXA-AS3 HOXA4 HOXA3 HOXA6 HOXA5 HOXA1 HOXA2
GH07I026855 Enhancer 1.3 Ensembl ENCODE dbSUPER 11.2 -250.2 -250229 4.8 HDAC1 PKNOX1 FEZF1 ZBTB40 TCF12 GLIS2 EGR1 ZNF366 EGR2 ZNF362 HOTAIRM1 HOXA5 HOXA-AS3 HOXA4 HOXA3 HOXA6 HOXA1 HOXA2 HOXA-AS2 SKAP2
GH07I027030 Enhancer 0.9 Ensembl ENCODE 10.4 -76.3 -76259 2 PKNOX1 RB1 SIN3A CEBPG ZNF384 FEZF1 ZIC2 POLR2A L3MBTL2 CEBPB HOTAIRM1 SKAP2 HOXA1 HOXA2 HOXA-AS2 HOXA3 TPM3P4 NHP2P2
GH07I026909 Enhancer 0.9 Ensembl ENCODE 10.1 -197.7 -197698 1.4 CTCF ELF3 JUN MAX RARA TEAD3 FOSL1 RCOR1 FOSL2 NR2F6 HOTAIRM1 SKAP2 HOXA2 HOXA-AS2 HOXA3 RPL7AP38 GC07P026846
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HOXA-AS2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for HOXA-AS2 Gene

Genomic Locations for HOXA-AS2 Gene
chr7:27,107,777-27,134,302
(GRCh38/hg38)
Size:
26,526 bases
Orientation:
Plus strand
chr7:27,147,396-27,173,921
(GRCh37/hg19)

Genomic View for HOXA-AS2 Gene

Genes around HOXA-AS2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HOXA-AS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HOXA-AS2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HOXA-AS2 Gene

Proteins for HOXA-AS2 Gene

Post-translational modifications for HOXA-AS2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HOXA-AS2 Gene

Domains & Families for HOXA-AS2 Gene

Gene Families for HOXA-AS2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HOXA-AS2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HOXA-AS2 Gene

Function for HOXA-AS2 Gene

Phenotypes From GWAS Catalog for HOXA-AS2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HOXA-AS2 Gene

Localization for HOXA-AS2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HOXA-AS2 Gene

Pathways & Interactions for HOXA-AS2 Gene

SuperPathways for HOXA-AS2 Gene

No Data Available

Interacting Proteins for HOXA-AS2 Gene

Gene Ontology (GO) - Biological Process for HOXA-AS2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HOXA-AS2 Gene

Drugs & Compounds for HOXA-AS2 Gene

No Compound Related Data Available

Transcripts for HOXA-AS2 Gene

mRNA/cDNA for HOXA-AS2 Gene

(7) Additional mRNA sequences :
(11) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HOXA-AS2 Gene

HOXA cluster antisense RNA 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HOXA-AS2 Gene

No ASD Table

Relevant External Links for HOXA-AS2 Gene

GeneLoc Exon Structure for
HOXA-AS2
ECgene alternative splicing isoforms for
HOXA-AS2

Expression for HOXA-AS2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HOXA-AS2 Gene

SOURCE GeneReport for Unigene cluster for HOXA-AS2 Gene:

Hs.714774
genes like me logo Genes that share expression patterns with HOXA-AS2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HOXA-AS2 Gene

Orthologs for HOXA-AS2 Gene

Evolution for HOXA-AS2 Gene

ENSEMBL:
Gene Tree for HOXA-AS2 (if available)
TreeFam:
Gene Tree for HOXA-AS2 (if available)

No data available for Orthologs for HOXA-AS2 Gene

Paralogs for HOXA-AS2 Gene

No data available for Paralogs for HOXA-AS2 Gene

Variants for HOXA-AS2 Gene

Sequence variations from dbSNP and Humsavar for HOXA-AS2 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000816682 -- 27,121,342(+) G/A upstream_transcript_variant
rs1000910670 -- 27,125,543(+) C/G intron_variant
rs1000960518 -- 27,127,498(+) T/C intron_variant
rs1001379085 -- 27,128,387(+) T/A non_coding_transcript_variant
rs1001544497 -- 27,128,830(+) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for HOXA-AS2 Gene

Variant ID Type Subtype PubMed ID
dgv1094n67 CNV gain 20364138
dgv11244n54 CNV loss 21841781
nsv5674 CNV deletion 18451855
nsv606464 CNV loss 21841781
nsv606465 CNV loss 21841781
nsv7393 OTHER inversion 18451855

Additional Variant Information for HOXA-AS2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HOXA-AS2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HOXA-AS2 Gene

Disorders for HOXA-AS2 Gene

Additional Disease Information for HOXA-AS2

No disorders were found for HOXA-AS2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HOXA-AS2 Gene

Publications for HOXA-AS2 Gene

  1. HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells. (PMID: 23649634) Zhao H … Newburger PE (Journal of cellular biochemistry 2013) 2 3 58
  2. Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer. (PMID: 28112720) Ding J … Wang K (Oncogenesis 2017) 3 58
  3. Upregulation of long non-coding RNA HOXA-AS2 promotes proliferation and induces epithelial-mesenchymal transition in gallbladder carcinoma. (PMID: 28388535) Zhang P … Gao Y (Oncotarget 2017) 3 58
  4. Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge. (PMID: 28545023) Fang Y … Zhang Q (Oncotarget 2017) 3 58
  5. Knockdown of HOXA-AS2 suppresses proliferation and induces apoptosis in colorectal cancer. (PMID: 29118916) Tong G … Wang S (American journal of translational research 2017) 3 58

Products for HOXA-AS2 Gene

Sources for HOXA-AS2 Gene

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