Aliases for HNRNPUL1 Gene
External Ids for HNRNPUL1 Gene
Previous HGNC Symbols for HNRNPUL1 Gene
Previous GeneCards Identifiers for HNRNPUL1 Gene
This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016]
GeneCards Summary for HNRNPUL1 Gene
HNRNPUL1 (Heterogeneous Nuclear Ribonucleoprotein U Like 1) is a Protein Coding gene. Diseases associated with HNRNPUL1 include Familial Hypercholesterolemia. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is HNRNPU.
UniProtKB/Swiss-Prot Summary for HNRNPUL1 Gene
Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.