Aliases for HNRNPLL Gene
External Ids for HNRNPLL Gene
Previous HGNC Symbols for HNRNPLL Gene
Previous GeneCards Identifiers for HNRNPLL Gene
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]
GeneCards Summary for HNRNPLL Gene
HNRNPLL (Heterogeneous Nuclear Ribonucleoprotein L Like) is a Protein Coding gene. Among its related pathways are Translational Control. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is HNRNPL.
UniProtKB/Swiss-Prot for HNRNPLL Gene
RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.