Aliases for HNRNPA0 Gene
External Ids for HNRNPA0 Gene
Previous HGNC Symbols for HNRNPA0 Gene
Previous GeneCards Identifiers for HNRNPA0 Gene
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008]
GeneCards Summary for HNRNPA0 Gene
HNRNPA0 (Heterogeneous Nuclear Ribonucleoprotein A0) is a Protein Coding gene. Among its related pathways are Translational Control and mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is HNRNPA3.
UniProtKB/Swiss-Prot Summary for HNRNPA0 Gene
mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs.