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Aliases for HNF1A-AS1 Gene

Subcategory (RNA class) for HNF1A-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for HNF1A-AS1 Gene

  • HNF1A Antisense RNA 1 2 3 5
  • HNF1A Antisense RNA 1 (Non-Protein Coding) 2 3
  • Chromosome 12 Open Reading Frame 27 2
  • Non-Protein Coding RNA 262 2
  • NCRNA00262 3
  • C12orf27 3
  • HAS1 3

External Ids for HNF1A-AS1 Gene

Previous HGNC Symbols for HNF1A-AS1 Gene

  • C12orf27
  • NCRNA00262

Previous GeneCards Identifiers for HNF1A-AS1 Gene

  • GC12M121406

Summaries for HNF1A-AS1 Gene

GeneCards Summary for HNF1A-AS1 Gene

HNF1A-AS1 (HNF1A Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with HNF1A-AS1 include Esophagus Adenocarcinoma and Adenocarcinoma.

Additional gene information for HNF1A-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HNF1A-AS1 Gene

Genomics for HNF1A-AS1 Gene

GeneHancer (GH) Regulatory Elements for HNF1A-AS1 Gene

Promoters and enhancers for HNF1A-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J120977 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 650.7 -0.2 -230 8.2 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF48 ETS1 YY1 SLC30A9 ZNF121 HNF1A HNF1A-AS1 PSMD9 PXN GCN1 SETD1B RPLP0 MLEC SPPL3 C12orf43
GH12J120580 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 11.7 +399.6 399572 1.9 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF213 E2F8 POP5 COQ5 GATC HNF1A-AS1 MLEC UNC119B C12orf43 ACADS ENSG00000256569 OASL
GH12J121143 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.8 -163.6 -163587 3 PKNOX1 ARNT IRF4 ZNF766 E2F8 ATF7 RUNX3 CAVIN1 JUNB MEF2D P2RX4 P2RX7 ANAPC5 GCN1 SETD1B HNF1A-AS1 ENSG00000272849 KDM2B SRSF9 CAMKK2
GH12J121708 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE 5.2 -732.5 -732483 9.8 PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 POLR2B ZNF143 TMEM120B PSMD9 ZCCHC8 KNTC1 RSRC2 SETD1B LOC101928346 KDM2B HPD ENSG00000256950
GH12J120583 Enhancer 1.1 Ensembl ENCODE 11.7 +396.8 396762 2 ARID4B SIN3A GLIS2 ZNF143 ZFP91 ATF7 REST GLIS1 MXD3 NCOA4 COQ5 GATC HNF1A-AS1 MLEC UNC119B C12orf43 ENSG00000256569 ACADS OASL DYNLL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HNF1A-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for HNF1A-AS1 Gene

Genomic Locations for HNF1A-AS1 Gene
chr12:120,941,728-120,980,965
(GRCh38/hg38)
Size:
39,238 bases
Orientation:
Minus strand
chr12:121,406,416-121,418,768
(GRCh37/hg19)
Size:
12,353 bases
Orientation:
Minus strand

Genomic View for HNF1A-AS1 Gene

Genes around HNF1A-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HNF1A-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HNF1A-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HNF1A-AS1 Gene

Proteins for HNF1A-AS1 Gene

Post-translational modifications for HNF1A-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HNF1A-AS1 Gene

Domains & Families for HNF1A-AS1 Gene

Gene Families for HNF1A-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HNF1A-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HNF1A-AS1 Gene

Function for HNF1A-AS1 Gene

Phenotypes From GWAS Catalog for HNF1A-AS1 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HNF1A-AS1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HNF1A-AS1 Gene

Localization for HNF1A-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HNF1A-AS1 Gene

Pathways & Interactions for HNF1A-AS1 Gene

SuperPathways for HNF1A-AS1 Gene

No Data Available

Interacting Proteins for HNF1A-AS1 Gene

Gene Ontology (GO) - Biological Process for HNF1A-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HNF1A-AS1 Gene

Drugs & Compounds for HNF1A-AS1 Gene

No Compound Related Data Available

Transcripts for HNF1A-AS1 Gene

mRNA/cDNA for HNF1A-AS1 Gene

(2) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(5) RNA Central transcripts :

Unigene Clusters for HNF1A-AS1 Gene

HNF1A antisense RNA 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HNF1A-AS1

Alternative Splicing Database (ASD) splice patterns (SP) for HNF1A-AS1 Gene

No ASD Table

Relevant External Links for HNF1A-AS1 Gene

GeneLoc Exon Structure for
HNF1A-AS1
ECgene alternative splicing isoforms for
HNF1A-AS1

Expression for HNF1A-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HNF1A-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for HNF1A-AS1 Gene

This gene is overexpressed in Stomach (x10.7), Liver (x10.4), Colon - Transverse (x10.0), Kidney - Cortex (x9.8), and Pancreas (x7.6).

SOURCE GeneReport for Unigene cluster for HNF1A-AS1 Gene:

Hs.612351
genes like me logo Genes that share expression patterns with HNF1A-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HNF1A-AS1 Gene

Orthologs for HNF1A-AS1 Gene

Evolution for HNF1A-AS1 Gene

ENSEMBL:
Gene Tree for HNF1A-AS1 (if available)
TreeFam:
Gene Tree for HNF1A-AS1 (if available)

No data available for Orthologs for HNF1A-AS1 Gene

Paralogs for HNF1A-AS1 Gene

No data available for Paralogs for HNF1A-AS1 Gene

Variants for HNF1A-AS1 Gene

Sequence variations from dbSNP and Humsavar for HNF1A-AS1 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1001507405 -- 120,971,096(-) C/T non_coding_transcript_variant
rs1002164154 -- 120,972,021(-) T/C/G non_coding_transcript_variant
rs1002261600 -- 120,971,772(-) C/G non_coding_transcript_variant
rs1003692606 -- 120,969,476(-) T/C downstream_transcript_variant
rs1004204738 -- 120,974,094(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for HNF1A-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv521928 CNV gain 19592680

Additional Variant Information for HNF1A-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HNF1A-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HNF1A-AS1 Gene

Disorders for HNF1A-AS1 Gene

MalaCards: The human disease database

(12) MalaCards diseases for HNF1A-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
esophagus adenocarcinoma
  • adenocarcinoma of esophagus
adenocarcinoma
  • adenocarcinomas
squamous cell carcinoma
  • epidermoid carcinoma
bladder cancer
  • bladder cancer, somatic
nasopharyngeal carcinoma
  • npca
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for HNF1A-AS1

genes like me logo Genes that share disorders with HNF1A-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HNF1A-AS1 Gene

Publications for HNF1A-AS1 Gene

  1. Long non-coding RNA HNF1A-AS1 mediated repression of miR-34a/SIRT1/p53 feedback loop promotes the metastatic progression of colon cancer by functioning as a competing endogenous RNA. (PMID: 28943452) Fang C … Yan D (Cancer letters 2017) 2 3 58
  2. The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma. (PMID: 25863539) Wu Y … Song Y (Oncotarget 2015) 2 3 58
  3. Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells. (PMID: 24000294) Yang X … Mori Y (Gut 2014) 2 3 58
  4. The lncRNA HNF1A-AS1 is a negative prognostic factor and promotes tumorigenesis in osteosarcoma. (PMID: 28866868) Cai L … Yang H (Journal of cellular and molecular medicine 2017) 3 58
  5. Long non-coding RNA HNF1A-AS1 promotes hepatocellular carcinoma cell proliferation by repressing NKD1 and P21 expression. (PMID: 28292020) Wang C … Zhang XY (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017) 3 58

Products for HNF1A-AS1 Gene

Sources for HNF1A-AS1 Gene

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