Aliases for HMGN1 Gene
Aliases for HMGN1 Gene
- High Mobility Group Nucleosome Binding Domain 1 2 3 5
- High Mobility Group Nucleosome-Binding Domain-Containing Protein 1 3 4
- High-Mobility Group (Nonhistone Chromosomal) Protein 14 2 3
- High-Mobility Group Nucleosome Binding 1 2 3
- Non-Histone Chromosomal Protein HMG-14 3 4
- Nonhistone Chromosomal Protein HMG-14 2 3
- HMG14 3 4
- High-Mobility Group Nucleosome Binding Domain 1 2
External Ids for HMGN1 Gene
- HGNC: 4984
- Entrez Gene: 3150
- Ensembl: ENSG00000205581
- OMIM: 163920
- UniProtKB: P05114
Previous HGNC Symbols for HMGN1 Gene
- HMG14
Previous GeneCards Identifiers for HMGN1 Gene
- GC21M037290
- GC21M039634
- GC21M039637
- GC21M040714
- GC21M026182
Summaries for HMGN1 Gene
-
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]
GeneCards Summary for HMGN1 Gene
HMGN1 (High Mobility Group Nucleosome Binding Domain 1) is a Protein Coding gene. Among its related pathways are Chromatin Regulation / Acetylation and ATM Signaling Network in Development and Disease. Gene Ontology (GO) annotations related to this gene include chromatin binding and nucleosomal DNA binding. An important paralog of this gene is HMGN3.
UniProtKB/Swiss-Prot for HMGN1 Gene
-
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HMGN1 Gene
Genomics for HMGN1 Gene
GeneHancer (GH) Regulatory Elements for HMGN1 Gene
Promoters and enhancers for HMGN1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HMGN1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the HMGN1 gene promoter:
-
- AREB6
- FOXD3
- FOXF2
- HNF-4alpha2
- Sox9
- SRF
- SRF (504 AA)
- TBP
- TFIID
Genomic Locations for HMGN1 Gene
Genomic Locations for HMGN1 Gene
- chr21:39,342,315-39,349,647
- (GRCh38/hg38)
- Size:
- 7,333 bases
- Orientation:
- Minus strand
- chr21:40,714,241-40,721,573
- (GRCh37/hg19)
- Size:
- 7,333 bases
- Orientation:
- Minus strand
Genomic View for HMGN1 Gene
Genes around HMGN1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 21q22.2 by HGNC
- 21q22.2 by Entrez Gene
- 21q22.2 by Ensembl
HMGN1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HMGN1 Gene
Proteins for HMGN1 Gene
-
Protein details for HMGN1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P05114-HMGN1_HUMAN
- Recommended name:
- Non-histone chromosomal protein HMG-14
- Protein Accession:
- P05114
- Q3KQR8
Protein attributes for HMGN1 Gene
- Size:
- 100 amino acids
- Molecular mass:
- 10659 Da
- Quaternary structure:
- No Data Available
Protein Expression for HMGN1 Gene
Post-translational modifications for HMGN1 Gene
- Phosphorylation on Ser-21 and Ser-25 weakens binding to nucleosomes and increases the rate of H3 phosphorylation (By similarity). Phosphorylation favors cytoplasmic localization.
- Ubiquitination at isoforms=14 and posLast=55
- Modification sites at PhosphoSitePlus
Other Protein References for HMGN1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-HMGN1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for HMGN1
- Novus Biologicals Antibodies for HMGN1
- Invitrogen Antibodies for HMGN1 (AFLGC-HMGN1)
- antibodies-online: Search results for 103 available HMGN1 Antibodies ranked by validation data
- Compare Top HMGN1 Antibodies
-
Recommended
- 58 WB Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
- 6 IHC (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-mouse)
- 20 WB Antibodies (anti-mouse)
- 5 IHC (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-rat)
- 17 WB Antibodies (anti-rat)
- 4 IHC (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
-
Boster Bio Antibodies for HMGN1
-
Santa Cruz Biotechnology (SCBT) Antibodies for HMGN1
Protein Products
- Atlas Antibodies PrEST Antigen HMGN1
-
OriGene Purified Proteins for HMGN1
- Search Origene for MassSpec and Protein Over-expression Lysates for HMGN1
- Origene Custom Protein Services for HMGN1
- ProSpec Recombinant Proteins for HMGN1
-
Abcam proteins for HMGN1
Assay Products
- Aviva Systems Biology HMGN1 ELISA Kit (Human) (OKEH01964) and HMGN1 ELISA Kit (Human) (OKCD07758)
No data available for DME Specific Peptides for HMGN1 Gene
Domains & Families for HMGN1 Gene
Gene Families for HMGN1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for HMGN1 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HMGN1 Gene
- GenScript: Design optimal peptide antigens:
-
- High mobility group nucleosome-binding domain-containing protein 1 (HMGN1_HUMAN)
- High-mobility group nucleosome binding domain 1 (Q3B790_HUMAN)
- High-mobility group nucleosome binding domain 1 (Q6NSG7_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P05114- Family:
-
- Belongs to the HMGN family.
Function for HMGN1 Gene
Molecular function for HMGN1 Gene
- UniProtKB/Swiss-Prot Function:
- Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).
Phenotypes From GWAS Catalog for HMGN1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | 8047885 |
| GO:0003682 | chromatin binding | IEA | -- |
| GO:0031492 | nucleosomal DNA binding | IEA | -- |
Phenotypes for HMGN1 Gene
- MGI mutant phenotypes for HMGN1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for HMGN1:
-
- Increased shRNA abundance (Z-score > 2)
- Decreased cell number
- Increased TP53 mRNA expression
- Decreased TP53 mRNA expression
- Reduced mammosphere formation
- Downregulation of Wnt pathway after Wnt3A stimulation
- Increased Nanog expression
- Decreased shRNA abundance (Z-score < -2)
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased hepcidin::fluc mRNA expression
- Decreased NF-kappaB reporter expression
- Increased viability
Animal Models for HMGN1 Gene
- MGI Knock Outs for HMGN1:
-
- Hmgn1 Hmgn1<tm1Mbus>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for HMGN1
-
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HMGN1 - Now 50% OFF >
- * HMGN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * HMGN1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for HMGN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HMGN1
- genomics-online: gRNA clones - Search results for 140 available HMGN1 gene related products
- Overview of 140 available HMGN1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for HMGN1
miRNA for HMGN1 Gene
- miRTarBase miRNAs that target HMGN1
-
- hsa-mir-197-3p (MIRT004185)
- hsa-mir-484 (MIRT041871)
- hsa-mir-125b-5p (MIRT045927)
- hsa-mir-100-5p (MIRT048518)
- hsa-mir-16-5p (MIRT051195)
- hsa-mir-27b-3p (MIRT454703)
- hsa-mir-27a-3p (MIRT454704)
- hsa-mir-513a-5p (MIRT454705)
- hsa-mir-570-3p (MIRT454706)
- hsa-mir-802 (MIRT454707)
- hsa-mir-4496 (MIRT454708)
- hsa-mir-7-2-3p (MIRT454709)
- hsa-mir-7-1-3p (MIRT454710)
- hsa-mir-5688 (MIRT454711)
- hsa-mir-495-3p (MIRT454712)
- hsa-mir-548at-5p (MIRT454713)
- hsa-mir-548ax (MIRT523155)
- hsa-mir-548ao-5p (MIRT523156)
- hsa-mir-32-3p (MIRT523157)
- hsa-mir-3662 (MIRT523158)
- hsa-mir-607 (MIRT687929)
- hsa-mir-3686 (MIRT687930)
- hsa-mir-3671 (MIRT687931)
- hsa-mir-3607-3p (MIRT687932)
- hsa-mir-4762-5p (MIRT687933)
- hsa-mir-4759 (MIRT687934)
- hsa-mir-140-3p (MIRT687935)
- hsa-mir-4700-3p (MIRT687936)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for HMGN1
- Browse OriGene Inhibitory RNA Products For HMGN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HMGN1
- genomics-online: shRNA clones - Search results for 140 available HMGN1 gene related products
- Overview of 140 available HMGN1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for HMGN1 - Now 50% OFF >
- * HMGN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * HMGN1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
-
- MG200269
- MR200269
- MR200269L1
- MR200269L1V
- MR200269L2
- MR200269L2V
- MR200269L3
- MR200269L3V
- MR200269L4
- MR200269L4V
- RC210454
- RC210454L1
- RC210454L1V
- RC210454L2
- RC210454L2V
- RC210454L3
- RC210454L3V
- RC210454L4
- RC210454L4V
- RG210454
- RR205499
- RR205499L1
- RR205499L1V
- RR205499L2
- RR205499L2V
- RR205499L3
- RR205499L3V
- RR205499L4
- RR205499L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HMGN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HMGN1
Cell Line Products
-
Horizon Cell Lines for HMGN1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HMGN1 Gene
Localization for HMGN1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HMGN1 Gene
- Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
- Nucleus (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | IEA | -- |
| GO:0005634 | nucleus | IDA,IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for HMGN1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | ||
| 2 | Chromatin Regulation / Acetylation | ||
| 3 | MAPK-Erk Pathway |
.38
|
|
| 4 | P38 MAPK Signaling Pathway (sino) | ||
| 5 | ERK Signaling |
.61
|
|
Pathways by source for HMGN1 Gene
2 Sino Biological pathways for HMGN1 Gene
2 BioSystems pathways for HMGN1 Gene
6 Reactome pathways for HMGN1 Gene
1 Qiagen pathway for HMGN1 Gene
1 Cell Signaling Technology pathway for HMGN1 Gene
Interacting Proteins for HMGN1 Gene
GPS-Prot Interaction Network for HMGN1
SIGNOR curated interactions for HMGN1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair | IEA | -- |
| GO:0006283 | transcription-coupled nucleotide-excision repair | IEA,TAS | -- |
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0010224 | response to UV-B | IEA | -- |
Drugs & Compounds for HMGN1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|
Drug Products
- Atlas Antibodies PrEST Antigen HMGN1
Transcripts for HMGN1 Gene
mRNA/cDNA for HMGN1 Gene
- (1) REFSEQ mRNAs :
- (16) Additional mRNA sequences :
- (792) Selected AceView cDNA sequences:
- (21) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000463631 583 bps (ENST00000463631.1)
- ENST00000482733 701 bps (ENST00000482733.1)
- ENST00000471260 615 bps (ENST00000471260.1)
- ENST00000479586 841 bps (ENST00000479586.5)
- ENST00000491183 527 bps (ENST00000491183.5)
Unigene Clusters for HMGN1 Gene
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HMGN1 - Now 50% OFF >
- * HMGN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * HMGN1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for HMGN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HMGN1
- genomics-online: gRNA clones - Search results for 140 available HMGN1 gene related products
- Overview of 140 available HMGN1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for HMGN1
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for HMGN1
- Browse OriGene Inhibitory RNA Products For HMGN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HMGN1
- genomics-online: shRNA clones - Search results for 140 available HMGN1 gene related products
- Overview of 140 available HMGN1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for HMGN1 - Now 50% OFF >
- * HMGN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * HMGN1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
-
- MG200269
- MR200269
- MR200269L1
- MR200269L1V
- MR200269L2
- MR200269L2V
- MR200269L3
- MR200269L3V
- MR200269L4
- MR200269L4V
- RC210454
- RC210454L1
- RC210454L1V
- RC210454L2
- RC210454L2V
- RC210454L3
- RC210454L3V
- RC210454L4
- RC210454L4V
- RG210454
- RR205499
- RR205499L1
- RR205499L1V
- RR205499L2
- RR205499L2V
- RR205499L3
- RR205499L3V
- RR205499L4
- RR205499L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for HMGN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HMGN1
Expression for HMGN1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- S-shaped Body Cells S-shaped Body
- S-shaped Body
- Metanephros
- Brain (Nervous System)
-
Eye (Sensory Organs)
- Fetal Corneal Basal Epithelial Cells Corneal Epithelium
- Adult Corneal Basal Epithelial Cells Corneal Epithelium
-
Epithelial Cells
- Fetal Corneal Basal Epithelial Cells Corneal Epithelium
- Adult Corneal Basal Epithelial Cells Corneal Epithelium
- Neural Tube (Nervous System)
- Blood (Hematopoietic System)
- Umbilical Cord (Extraembryonic Tissues)
- Bone (Muscoskeletal System)
- Thymus (Hematopoietic System)
- Endoderm (Gastrulation Derivatives)
This gene is overexpressed in Stomach (13.4), Lavage (13.0), and Nasal epithelium (11.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HMGN1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HMGN1 Gene:
HMGN1SOURCE GeneReport for Unigene cluster for HMGN1 Gene:
Hs.356285Evidence on tissue expression from TISSUES for HMGN1 Gene
- Nervous system(4.9)
- Liver(4.6)
- Blood(4.5)
- Bone marrow(4.4)
- Lung(3.5)
- Eye(3.3)
- Intestine(2.7)
- Spleen(2.5)
- Thyroid gland(2.5)
- Kidney(2.2)
- Pancreas(2.2)
- Lymph node(2.1)
Primer Products
-
OriGene qPCR primer pairs for HMGN1
-
OriGene qPCR primer pairs and template standards for HMGN1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HMGN1 Gene
Orthologs for HMGN1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HMGN1 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HMGN1 35 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | HMGN1 35 34 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Hmgn1 35 17 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | LOC100911295 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HMGN1 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | HMGN1 35 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | HMGN1 35 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | hmgn1-prov 34 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | MGC75785 34 |
|
- Species where no ortholog for HMGN1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for HMGN1 Gene
- ENSEMBL:
- Gene Tree for HMGN1 (if available)
- TreeFam:
- Gene Tree for HMGN1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HMGN1: view image
Paralogs for HMGN1 Gene
(2) SIMAP similar genes for HMGN1 Gene using alignment to 9 proteins:
- HMGN1_HUMAN
- A6NEL0_HUMAN
- A6NGZ2_HUMAN
- A6NL93_HUMAN
- F2Z2W6_HUMAN
- F2Z2Y5_HUMAN
- H7BXJ5_HUMAN
- Q3B790_HUMAN
- Q6NSG7_HUMAN
Pseudogenes.org Pseudogenes for HMGN1 Gene
- PGOHUM00000290349
- PGOHUM00000290397
- PGOHUM00000290851
- PGOHUM00000291267
- PGOHUM00000291562
- PGOHUM00000292031
- PGOHUM00000292392
- PGOHUM00000292764
- PGOHUM00000292982
- PGOHUM00000293302
- PGOHUM00000294447
- PGOHUM00000294502
- PGOHUM00000294670
- PGOHUM00000294676
- PGOHUM00000295125
- PGOHUM00000295983
- PGOHUM00000297369
- PGOHUM00000298298
- PGOHUM00000306571
- PGOHUM00000299606
- PGOHUM00000300223
- PGOHUM00000300715
- PGOHUM00000300720
- PGOHUM00000302618
- PGOHUM00000302905
- PGOHUM00000304919
- PGOHUM00000305128
- PGOHUM00000288953
- PGOHUM00000288973
- PGOHUM00000290054
Variants for HMGN1 Gene
| SNP ID | Clin | Chr 21 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000433303 | -- | 39,348,761(-) | G/A | intron_variant | |
| rs1000697562 | -- | 39,343,010(-) | G/C | 3_prime_UTR_variant, coding_sequence_variant, missense_variant | |
| rs1000868318 | -- | 39,347,932(-) | G/A | 5_prime_UTR_variant, intron_variant | |
| rs1001153863 | -- | 39,342,273(-) | T/A | downstream_transcript_variant | |
| rs1001207425 | -- | 39,348,072(-) | C/T | 5_prime_UTR_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2389n106 | CNV | deletion | 24896259 |
| nsv1073129 | CNV | deletion | 25765185 |
| nsv587483 | CNV | loss | 21841781 |
| nsv979537 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
87.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.26;
62.53% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HMGN1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HMGN1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HMGN1 Gene
Disorders for HMGN1 Gene
Additional Disease Information for HMGN1
No disorders were found for HMGN1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HMGN1 Gene
Publications for HMGN1 Gene
- Phosphorylation and subcellular redistribution of high mobility group proteins 14 and 17, analyzed by mass spectrometry. (PMID: 10739259) Louie DF … Ahn NG (Protein science : a publication of the Protein Society 2000) 3 4 23 58
- Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family. (PMID: 2563381) Landsman D … Bustin M (The Journal of biological chemistry 1989) 2 3 4 58
- Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family. (PMID: 3782107) Landsman D … Bustin M (The Journal of biological chemistry 1986) 2 3 4 58
- Serine ADP-Ribosylation Depends on HPF1. (PMID: 28190768) Bonfiglio JJ … Matic I (Molecular cell 2017) 3 4 58
- HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility. (PMID: 19524541) Rattner BP … Kadonaga JT (Molecular cell 2009) 3 23 58
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Products for HMGN1 Gene
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Sources for HMGN1 Gene
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