Aliases for HMG20A Gene
External Ids for HMG20A Gene
Previous GeneCards Identifiers for HMG20A Gene
GeneCards Summary for HMG20A Gene
HMG20A (High Mobility Group 20A) is a Protein Coding gene. Diseases associated with HMG20A include Autosomal Recessive Congenital Cerebellar Ataxia and Cowpox. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and chromatin binding. An important paralog of this gene is HMG20B.
UniProtKB/Swiss-Prot Summary for HMG20A Gene
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity).