Aliases for HMCN1 Gene
External Ids for HMCN1 Gene
Previous HGNC Symbols for HMCN1 Gene
Previous GeneCards Identifiers for HMCN1 Gene
This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]
GeneCards Summary for HMCN1 Gene
HMCN1 (Hemicentin 1) is a Protein Coding gene. Diseases associated with HMCN1 include Macular Degeneration, Age-Related, 1 and Cardiomyopathy, Dilated, 1L. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is OBSCN.
UniProtKB/Swiss-Prot Summary for HMCN1 Gene
Promotes cleavage furrow maturation during cytokinesis in preimplantation embryos. May play a role in the architecture of adhesive and flexible epithelial cell junctions. May play a role during myocardial remodeling by imparting an effect on cardiac fibroblast migration.