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Aliases for HLX Gene
Aliases for HLX Gene
External Ids for HLX Gene
- HGNC: 4978
- Entrez Gene: 3142
- Ensembl: ENSG00000136630
- OMIM: 142995
- UniProtKB: Q14774
Previous HGNC Symbols for HLX Gene
- HLX1
Previous GeneCards Identifiers for HLX Gene
- GC01P219120
- GC01P221052
- GC01P191727
Summaries for HLX Gene
GeneCards Summary for HLX Gene
HLX (H2.0 Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include Diaphragmatic Hernia-Short Bowel-Asplenia Syndrome and Osteogenesis Imperfecta, Type Vii. Among its related pathways are IL12-mediated signaling events. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DBX1.
UniProtKB/Swiss-Prot Summary for HLX Gene
-
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
Additional gene information for HLX Gene
- HGNC(4978)
- Entrez Gene(3142)
- Ensembl(ENSG00000136630)
- OMIM(142995)
- UniProtKB(Q14774)
- Open Targets Platform(ENSG00000136630)
- Search for HLX at DataMed
- Search for HLX at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HLX Gene
Genomics for HLX Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HLX Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HLX on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HLX
- Top Transcription factor binding sites by QIAGEN in the HLX gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- IRF-1
- Sox5
- STAT1
Genomic Locations for HLX Gene
Genomic Locations for HLX Gene
- chr1:220,879,431-220,885,059
- (GRCh38/hg38)
- Size:
- 5,629 bases
- Orientation:
- Plus strand
- chr1:221,051,699-221,058,401
- (GRCh37/hg19)
- Size:
- 6,703 bases
- Orientation:
- Plus strand
Genomic View for HLX Gene
Genes around HLX on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q41 by HGNC
- 1q41 by Entrez Gene
- 1q41 by Ensembl
HLX Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HLX Gene
Proteins for HLX Gene
-
Protein details for HLX Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14774-HLX_HUMAN
- Recommended name:
- H2.0-like homeobox protein
- Protein Accession:
- Q14774
- B2R8A8
- Q15988
- Q59HE7
- Q9NZ75
Protein attributes for HLX Gene
- Size:
- 488 amino acids
- Molecular mass:
- 50789 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAD92049.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAD92049.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=M60721; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for HLX Gene
Post-translational modifications for HLX Gene
Other Protein References for HLX Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ HLX1 Antibody
- Novus Biologicals Antibodies for HLX
-
Abcam antibodies for HLX
- Invitrogen Antibodies for HLX (AFLGC-HLX)
-
Santa Cruz Biotechnology (SCBT) Antibodies for HLX
Protein Products
-
OriGene Purified Proteins for HLX
- Search Origene for MassSpec and Protein Over-expression Lysates for HLX
- Origene Custom Protein Services for HLX
- antibodies-online: Show 6 available HLX Proteins ranked by validation data
- Compare Top HLX Proteins
-
Abcam proteins for HLX
No data available for DME Specific Peptides for HLX Gene
Domains & Families for HLX Gene
Gene Families for HLX Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for HLX Gene
- InterPro:
- Blocks:
-
- Lambda and other repressor helix-turn-helix signature
- ProtoNet:
Suggested Antigen Peptide Sequences for HLX Gene
- GenScript: Design optimal peptide antigens:
-
- Homeobox protein HLX1 (HLX_HUMAN)
- HLX1 protein (Q15989_HUMAN)
- H2.0-like homeobox (Q5VVT2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q14774- Family:
-
- Belongs to the H2.0 homeobox family.
Function for HLX Gene
Molecular function for HLX Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).
Phenotypes From GWAS Catalog for HLX Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 23455154 |
| GO:0043565 | sequence-specific DNA binding | IEA,IDA | 9073066 |
Phenotypes for HLX Gene
- MGI mutant phenotypes for HLX:
-
inferred from 1 alleles
- nervous system phenotype
- respiratory system phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- liver/biliary system phenotype
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- hematopoietic system phenotype
- integument phenotype
- GenomeRNAi human phenotypes for HLX:
Animal Models for HLX Gene
- MGI Knock Outs for HLX:
-
- Hlx Hlx<tm1Rph>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HLX - Select products 50% OFF >
- * HLX CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HLX
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HLX
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLX
miRNA for HLX Gene
- miRTarBase miRNAs that target HLX
-
- hsa-miR-1260b (MIRT052679)
- hsa-miR-5572 (MIRT717631)
- hsa-miR-4260 (MIRT717632)
- hsa-miR-450a-2-3p (MIRT717633)
- hsa-miR-6857-5p (MIRT717634)
- hsa-miR-6763-5p (MIRT717635)
- hsa-miR-3150a-3p (MIRT717636)
- hsa-miR-6810-5p (MIRT717637)
- hsa-miR-2110 (MIRT717638)
- hsa-miR-4423-3p (MIRT717639)
- hsa-miR-6825-5p (MIRT717640)
- hsa-miR-939-5p (MIRT717641)
- hsa-miR-1343-5p (MIRT717642)
- hsa-miR-3175 (MIRT717643)
- hsa-miR-6878-5p (MIRT717644)
- hsa-miR-3670 (MIRT717645)
- hsa-miR-645 (MIRT717646)
- hsa-miR-3622a-5p (MIRT717647)
- hsa-miR-5582-5p (MIRT717648)
- hsa-miR-1276 (MIRT717649)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HLX
- Browse OriGene Inhibitory RNA Products For HLX
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HLX
Clone Products
- Applied Biological Materials (abm): Clones for HLX - Select products 50% OFF >
- * HLX as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HLX
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HLX
Cell Line Products
-
Horizon Cell Lines for HLX
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HLX Gene
Localization for HLX Gene
Subcellular locations from UniProtKB/Swiss-Prot for HLX Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for HLX Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | IL12-mediated signaling events | ||
Pathways by source for HLX Gene
1 BioSystems pathway for HLX Gene
Interacting Proteins for HLX Gene
Selected Interacting proteins:
Q14774-HLX_HUMAN
ENSP00000355870
for HLX Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for HLX
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001889 | liver development | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0007275 | multicellular organism development | TAS | 8094082 |
| GO:0007519 | skeletal muscle tissue development | IEA | -- |
Transcripts for HLX Gene
mRNA/cDNA for HLX Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000366903 2237 nts (view in UCSC)
- ENST00000427693 695 nts (view in UCSC)
- ENST00000549319 5626 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HLX - Select products 50% OFF >
- * HLX CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HLX
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HLX
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLX
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HLX
- Browse OriGene Inhibitory RNA Products For HLX
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HLX
Clone Products
- Applied Biological Materials (abm): Clones for HLX - Select products 50% OFF >
- * HLX as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HLX
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HLX
Relevant External Links for HLX Gene
- GeneLoc Exon Structure for
- HLX
Expression for HLX Gene
mRNA differential expression in normal tissues according to GTEx for HLX Gene
This gene is overexpressed in Whole Blood (x8.1) and Colon - Sigmoid (x4.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HLX Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HLX
SOURCE GeneReport for Unigene cluster for HLX Gene:
Hs.74870mRNA Expression by UniProt/SwissProt for HLX Gene:
Q14774-HLX_HUMAN
Tissue specificity:
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Evidence on tissue expression from TISSUES for HLX Gene
- Nervous system(4.4)
- Intestine(4.4)
- Eye(4.2)
- Bone marrow(2.5)
- Liver(2.2)
- Heart(2.1)
- Blood(2.1)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for HLX
-
OriGene qPCR primer pairs and template standards for HLX
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for HLX Gene
Orthologs for HLX Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HLX 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | HLX 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | HLX 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Hlx 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Hlx 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | HLX 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | HLX 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | HLX 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | HLX 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | hlx 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | hlx1 30 31 |
|
OneToOne | |
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2656 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | H2.0 31 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for HLX was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for HLX Gene
- ENSEMBL:
- Gene Tree for HLX (if available)
- TreeFam:
- Gene Tree for HLX (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HLX: view image
Paralogs for HLX Gene
(29) SIMAP similar genes for HLX Gene using alignment to 3 proteins:
- HLX_HUMAN
- F8VVX3_HUMAN
- F8VWZ5_HUMAN
Variants for HLX Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HLX Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 777942 | Benign: not provided | 220,884,186(+) | G/A | INTRON_VARIANT | |
| 779861 | Benign: not provided | 220,881,305(+) | C/T | MISSENSE_VARIANT | |
| rs11578466 | - | p.Ala387Gly | |||
| rs12141189 | - | p.Ser116Pro | |||
| rs2738755 | - | p.Pro356Leu |
Residual Variation Intolerance Score:
55.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
12.70;
94.63% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HLX Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HLX Gene
Disorders for HLX Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| diaphragmatic hernia-short bowel-asplenia syndrome |
|
|
| osteogenesis imperfecta, type vii |
|
|
| ovarian endodermal sinus tumor |
|
|
| ovarian primitive germ cell tumor |
|
|
| osteogenesis imperfecta, type iv |
|
|
Search HLX in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HLX
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for HLX Gene
Publications for HLX Gene
- Cloning of a human homeobox gene that resembles a diverged Drosophila homeobox gene and is expressed in activated lymphocytes. (PMID: 1676597) Deguchi Y … Kehrl JH (The New biologist 1991) 2 3 4 23
- Genomic structure, promoter sequence, and revised translation of human homeobox gene HLX1. (PMID: 7806220) Kennedy MA … Morris CM (Genomics 1994) 2 3 4
- Linkage localization of TGFB2 and the human homeobox gene HLX1 to chromosome 1q. (PMID: 8095486) Nishimura DY … Murray JC (Genomics 1993) 3 4 23
- TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. (PMID: 19362357) Suttner K … Kabesch M (The Journal of allergy and clinical immunology 2009) 3 41
- HLX1 gene variants influence the development of childhood asthma. (PMID: 19038437) Suttner K … Kabesch M (The Journal of allergy and clinical immunology 2009) 3 41
ExternalLinks
Products for HLX Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HLX
- Search Origene for MassSpec and Protein Over-expression Lysates for HLX
- Origene Custom Protein Services for HLX
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HLX
- Browse OriGene Inhibitory RNA Products For HLX
- OriGene qPCR primer pairs for HLX
- OriGene qPCR primer pairs and template standards for HLX
- OriGene CRISPR knockouts for HLX
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HLX
- Sino Biological Human cDNA Clone for HLX
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for HLX
- Novus Biologicals proteins and lysates for HLX
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for HLX
- Abcam proteins for HLX
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for HLX (AFLGC-HLX)
- VectorBuilder Custom and pre-made DNA vectors for HLX (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for HLX (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HLX (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HLX CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HLX
- antibodies-online: Show 19 available HLX Antibodies ranked by validation data
- Compare Top HLX Antibodies
- antibodies-online: Search results for available HLX related products ranked by validation data
- antibodies-online: Show 6 available HLX Proteins ranked by validation data
- Compare Top HLX Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for HLX
- Search Santa Cruz Biotechnology (SCBT) for HLX siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HLX
- Horizon Cell Lines for HLX
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HLX
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HLX
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HLX
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HLX
Sources for HLX Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB