Aliases for HLX Gene
External Ids for HLX Gene
Previous HGNC Symbols for HLX Gene
Previous GeneCards Identifiers for HLX Gene
GeneCards Summary for HLX Gene
HLX (H2.0 Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include Diaphragmatic Hernia-Short Bowel-Asplenia Syndrome and Ovarian Endodermal Sinus Tumor. Among its related pathways are IL12-mediated signaling events. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DBX1.
UniProtKB/Swiss-Prot Summary for HLX Gene
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity).