Aliases for HLF Gene
External Ids for HLF Gene
Previous GeneCards Identifiers for HLF Gene
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for HLF Gene
HLF (HLF, PAR BZIP Transcription Factor) is a Protein Coding gene. Diseases associated with HLF include Leukemia, Acute Lymphoblastic 3 and Leukemia. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and double-stranded DNA binding. An important paralog of this gene is TEF.