This major histocompatibility complex gene represents a transcribed pseudogene, possibly derived from HLA-A. [provided by RefSeq, May 2010] See more...

Aliases for HLA-J Gene

Aliases for HLA-J Gene

  • Major Histocompatibility Complex, Class I, J (Pseudogene) 2 3 5
  • HLA-59 2 3
  • CDA12 2 3
  • HLA-CDA12 3
  • D6S203 3
  • HLA-J 5

External Ids for HLA-J Gene

Previous HGNC Symbols for HLA-J Gene

  • HLA-CDA12
  • D6S203

Previous GeneCards Identifiers for HLA-J Gene

  • GC06U990057
  • GC06M030029
  • GC06P029857
  • GC06P029905
  • GC06P030018
  • GC06P029908
  • GC06P029909
  • GC06P029910
  • GC06P030082
  • GC06P030073
  • GC06P029979
  • GC06P029984
  • GC06P029989
  • GC06P029998
  • GC06P030190
  • GC06P030222
  • GC06P030260
  • GC06P032259
  • GC06P032433
  • GC06P032564
  • GC06P033213
  • GC06P030359
  • GC06P030507
  • GC06P030714
  • GC06P030872
  • GC06P031032
  • GC06P031184
  • GC06P031364
  • GC06P031966

Summaries for HLA-J Gene

Entrez Gene Summary for HLA-J Gene

  • This major histocompatibility complex gene represents a transcribed pseudogene, possibly derived from HLA-A. [provided by RefSeq, May 2010]

GeneCards Summary for HLA-J Gene

HLA-J (Major Histocompatibility Complex, Class I, J (Pseudogene)) is a Pseudogene. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation.

Additional gene information for HLA-J Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HLA-J Gene

Genomics for HLA-J Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for HLA-J Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HLA-J on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the HLA-J gene promoter:
  • ATF6
  • E4BP4
  • ER-alpha
  • GATA-3
  • HEN1
  • HSF1 (long)
  • HSF1short
  • HSF2
  • p53

Genomic Locations for HLA-J Gene

Genomic Locations for HLA-J Gene
chr6:30,005,971-30,009,956
(GRCh38/hg38)
Size:
3,986 bases
Orientation:
Plus strand
chr6:29,973,748-29,977,733
(GRCh37/hg19)
Size:
3,986 bases
Orientation:
Plus strand

Genomic View for HLA-J Gene

Genes around HLA-J on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-J Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-J Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HLA-J Gene

Post-translational modifications for HLA-J Gene

No Post-translational modifications

No data available for DME Specific Peptides for HLA-J Gene

Domains & Families for HLA-J Gene

Gene Families for HLA-J Gene

Suggested Antigen Peptide Sequences for HLA-J Gene

GenScript: Design optimal peptide antigens:
  • MHC class I HLA-J antigen (Q30175_HUMAN)
genes like me logo Genes that share domains with HLA-J: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for HLA-J Gene

Function for HLA-J Gene

Molecular function for HLA-J Gene

GENATLAS Biochemistry:
HLA class I-like gene J,5.9 Hind III fragment,see MHC1

Phenotypes From GWAS Catalog for HLA-J Gene

genes like me logo Genes that share phenotypes with HLA-J: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HLA-J Gene

Localization for HLA-J Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HLA-J Gene

Pathways & Interactions for HLA-J Gene

PathCards logo

SuperPathways for HLA-J Gene

genes like me logo Genes that share pathways with HLA-J: view

Pathways by source for HLA-J Gene

1 BioSystems pathway for HLA-J Gene

Gene Ontology (GO) - Biological Process for HLA-J Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for HLA-J Gene

Drugs & Compounds for HLA-J Gene

No Compound Related Data Available

Transcripts for HLA-J Gene

mRNA/cDNA for HLA-J Gene

4 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-J Gene

No ASD Table

Relevant External Links for HLA-J Gene

GeneLoc Exon Structure for
HLA-J

Expression for HLA-J Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for HLA-J Gene

mRNA differential expression in normal tissues according to GTEx for HLA-J Gene

This gene is overexpressed in Whole Blood (x7.3).

Protein differential expression in normal tissues from HIPED for HLA-J Gene

This gene is overexpressed in Skin (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for HLA-J Gene



Protein tissue co-expression partners for HLA-J Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HLA-J

SOURCE GeneReport for Unigene cluster for HLA-J Gene:

Hs.720762
genes like me logo Genes that share expression patterns with HLA-J: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HLA-J Gene

Orthologs for HLA-J Gene

Evolution for HLA-J Gene

ENSEMBL:
Gene Tree for HLA-J (if available)
TreeFam:
Gene Tree for HLA-J (if available)

No data available for Orthologs for HLA-J Gene

Paralogs for HLA-J Gene

genes like me logo Genes that share paralogs with HLA-J: view

No data available for Paralogs for HLA-J Gene

Variants for HLA-J Gene

Structural Variations from Database of Genomic Variants (DGV) for HLA-J Gene

Variant ID Type Subtype PubMed ID
dgv1088e199 CNV deletion 23128226
dgv993e201 CNV deletion 23290073
esv2641340 CNV deletion 19546169
esv2731777 CNV deletion 23290073
esv2731778 CNV deletion 23290073
esv2759412 CNV gain+loss 17122850
esv3411275 CNV duplication 20981092
esv3570888 CNV loss 25503493
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1144137 CNV deletion 24896259
nsv508398 CNV deletion 20534489
nsv601264 CNV loss 21841781
nsv601475 CNV loss 21841781
nsv981126 CNV duplication 23825009

Additional Variant Information for HLA-J Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HLA-J

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for HLA-J Gene

Disorders for HLA-J Gene

Additional Disease Information for HLA-J

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for HLA-J Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HLA-J Gene

Publications for HLA-J Gene

  1. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. (PMID: 20593013) Cree BA … IMSGC (PloS one 2010) 3 41
  2. HLA-J, a second inactivated class I HLA gene related to HLA-G and HLA-A. Implications for the evolution of the HLA-A-related genes. (PMID: 1602142) Messer G … Girdlestone J (Journal of immunology (Baltimore, Md. : 1950) 1992) 2 3
  3. Paradoxical downregulation of HLA-A expression by IFNγ associated with schizophrenia and noncoding genes. (PMID: 23083632) Gu S … Wank R (Immunobiology 2013) 3
  4. Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. (PMID: 21900946) Nakabayashi K … Shirasawa S (Journal of human genetics 2011) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3

Products for HLA-J Gene

Sources for HLA-J Gene