Aliases for HLA-B Gene
Aliases for HLA-B Gene
- Major Histocompatibility Complex, Class I, B 2 3 5
- HLAB 3 4
- HLA Class I Histocompatibility Antigen, B-12 Alpha Chain 4
- HLA Class I Histocompatibility Antigen, B-21 Alpha Chain 4
- HLA Class I Histocompatibility Antigen, B-5 Alpha Chain 4
- HLA Class I Histocompatibility Antigen, B Alpha Chain 3
- MHC Class I Antigen HLA-B Alpha Chain 3
- MHC Class I Antigen HLA-B Heavy Chain 3
- MHC HLA-B Transmembrane Glycoprotein 3
- MHC HLA-B Cell Surface Glycoprotein 3
- Leukocyte Antigen Class I-B 3
- HLA Class I Antigen HLA-B 3
- MHC Class I Antigen SHCHA 3
- MHC Class I Antigen B*13 4
- MHC Class I Antigen B*14 4
- MHC Class I Antigen B*15 4
- MHC Class I Antigen B*18 4
- MHC Class I Antigen B*27 4
- MHC Class I Antigen B*35 4
- MHC Class I Antigen B*37 4
- MHC Class I Antigen B*38 4
- MHC Class I Antigen B*39 4
- MHC Class I Antigen B*40 4
- MHC Class I Antigen B*41 4
- MHC Class I Antigen B*42 4
- MHC Class I Antigen B*44 4
- MHC Class I Antigen B*45 4
- MHC Class I Antigen B*46 4
- MHC Class I Antigen B*47 4
- MHC Class I Antigen B*48 4
- MHC Class I Antigen B*49 4
- MHC Class I Antigen B*50 4
- MHC Class I Antigen B*51 4
- MHC Class I Antigen B*52 4
- MHC Class I Antigen B*53 4
- MHC Class I Antigen B*54 4
- MHC Class I Antigen B*55 4
- MHC Class I Antigen B*56 4
- MHC Class I Antigen B*57 4
- MHC Class I Antigen B*58 4
- MHC Class I Antigen B*59 4
- MHC Class I Antigen B*67 4
- MHC Class I Antigen B*73 4
- MHC Class I Antigen B*78 4
- MHC Class I Antigen B*81 4
- MHC Class I Antigen B*82 4
- MHC Class I Antigen B*7 4
- MHC Class I Antigen B*8 4
- Ankylosing Spondylitis 2
- MHC Class I Molecule 3
- MHC Class 1 Antigen 3
- B-4901 3
- Bw-22 4
- Bw-41 4
- Bw-44 4
- Bw-45 4
- Bw-46 4
- Bw-47 4
- Bw-48 4
- Bw-50 4
- Bw-52 4
- Bw-53 4
- Bw-54 4
- Bw-55 4
- Bw-56 4
- Bw-57 4
- Bw-58 4
- Bw-60 4
- Bw-4 4
- BDT 4
- AS 3
External Ids for HLA-B Gene
- HGNC: 4932
- Entrez Gene: 3106
- Ensembl: ENSG00000234745
- OMIM: 142830
- UniProtKB: P01889
- UniProtKB: P03989
- UniProtKB: P10319
- UniProtKB: P18463
- UniProtKB: P18464
- UniProtKB: P18465
- UniProtKB: P30460
- UniProtKB: P30461
- UniProtKB: P30462
- UniProtKB: P30464
- UniProtKB: P30466
- UniProtKB: P30475
- UniProtKB: P30479
- UniProtKB: P30480
- UniProtKB: P30481
- UniProtKB: P30483
- UniProtKB: P30484
- UniProtKB: P30485
- UniProtKB: P30486
- UniProtKB: P30487
- UniProtKB: P30488
- UniProtKB: P30490
- UniProtKB: P30491
- UniProtKB: P30492
- UniProtKB: P30493
- UniProtKB: P30495
- UniProtKB: P30498
- UniProtKB: P30685
- UniProtKB: Q04826
- UniProtKB: Q29718
- UniProtKB: Q29836
- UniProtKB: Q29940
- UniProtKB: Q31610
- UniProtKB: Q31612
- UniProtKB: Q95365
Previous HGNC Symbols for HLA-B Gene
- AS
Previous GeneCards Identifiers for HLA-B Gene
- GC06M031376
- GC06M031426
- GC06M031342
- GC06M031429
- GC06M031345
- GC06M031321
- GC06M031112
- GC06M031354
Summaries for HLA-B Gene
-
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for HLA-B Gene
HLA-B (Major Histocompatibility Complex, Class I, B) is a Protein Coding gene. Diseases associated with HLA-B include Severe Cutaneous Adverse Reaction and Spondyloarthropathy 1. Among its related pathways are Cytokine Signaling in Immune system and Allograft rejection. Gene Ontology (GO) annotations related to this gene include receptor binding and peptide antigen binding. An important paralog of this gene is HLA-C.
UniProtKB/Swiss-Prot for HLA-B Gene
- 1B07_HUMAN,P01889
- 1B08_HUMAN,P30460
- 1B13_HUMAN,P30461
- 1B14_HUMAN,P30462
- 1B15_HUMAN,P30464
- 1B18_HUMAN,P30466
- 1B27_HUMAN,P03989
- 1B35_HUMAN,P30685
- 1B37_HUMAN,P18463
- 1B38_HUMAN,Q95365
- 1B39_HUMAN,P30475
- 1B40_HUMAN,Q04826
- 1B41_HUMAN,P30479
- 1B42_HUMAN,P30480
- 1B44_HUMAN,P30481
- 1B45_HUMAN,P30483
- 1B46_HUMAN,P30484
- 1B47_HUMAN,P30485
- 1B48_HUMAN,P30486
- 1B49_HUMAN,P30487
- 1B50_HUMAN,P30488
- 1B51_HUMAN,P18464
- 1B52_HUMAN,P30490
- 1B53_HUMAN,P30491
- 1B54_HUMAN,P30492
- 1B55_HUMAN,P30493
- 1B56_HUMAN,P30495
- 1B57_HUMAN,P18465
- 1B58_HUMAN,P10319
- 1B59_HUMAN,Q29940
- 1B67_HUMAN,Q29836
- 1B73_HUMAN,Q31612
- 1B78_HUMAN,P30498
- 1B81_HUMAN,Q31610
- 1B82_HUMAN,Q29718
-
Involved in the presentation of foreign antigens to the immune system.
Additional gene information for HLA-B Gene
- HGNC(4932)
- Entrez Gene(3106)
- Ensembl(ENSG00000234745)
- OMIM(142830)
- UniProtKB(P01889)
- UniProtKB(P03989)
- UniProtKB(P10319)
- UniProtKB(P18463)
- UniProtKB(P18464)
- UniProtKB(P18465)
- UniProtKB(P30460)
- UniProtKB(P30461)
- UniProtKB(P30462)
- UniProtKB(P30464)
- UniProtKB(P30466)
- UniProtKB(P30475)
- UniProtKB(P30479)
- UniProtKB(P30480)
- UniProtKB(P30481)
- UniProtKB(P30483)
- UniProtKB(P30484)
- UniProtKB(P30485)
- UniProtKB(P30486)
- UniProtKB(P30487)
- UniProtKB(P30488)
- UniProtKB(P30490)
- UniProtKB(P30491)
- UniProtKB(P30492)
- UniProtKB(P30493)
- UniProtKB(P30495)
- UniProtKB(P30498)
- UniProtKB(P30685)
- UniProtKB(Q04826)
- UniProtKB(Q29718)
- UniProtKB(Q29836)
- UniProtKB(Q29940)
- UniProtKB(Q31610)
- UniProtKB(Q31612)
- UniProtKB(Q95365)
- Monarch Initiative
- Search for HLA-B at DataMed
- Search for HLA-B at HumanCyc
No data available for CIViC summary , Tocris Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-B Gene
Genomics for HLA-B Gene
GeneHancer (GH) Regulatory Elements for HLA-B Gene
Promoters and enhancers for HLA-B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around HLA-B on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for HLA-B Gene
Genomic Locations for HLA-B Gene
- chr6:31,269,491-31,357,212
- (GRCh38/hg38)
- Size:
- 87,722 bases
- Orientation:
- Minus strand
- chr6:31,321,649-31,324,989
- (GRCh37/hg19)
Genomic View for HLA-B Gene
Genes around HLA-B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.33 by Ensembl
- 6p21.33 by Entrez Gene
- 6p21.33 by HGNC
HLA-B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HLA-B Gene
Proteins for HLA-B Gene
-
Protein details for HLA-B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P01889-1B07_HUMAN
- Recommended name:
- HLA class I histocompatibility antigen, B-7 alpha chain
- Protein Accession:
- P01889
- Q29638
- Q29681
- Q29854
- Q29861
- Q31613
- Q5SRJ2
- Q9GIX1
- Q9TP95
Protein attributes for HLA-B Gene
- Size:
- 362 amino acids
- Molecular mass:
- 40460 Da
- Quaternary structure:
-
- Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein (By similarity). Interacts with HTLV-1 accessory protein p12I.
Protein Expression for HLA-B Gene
Post-translational modifications for HLA-B Gene
-
Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).
- P01889-1B07_HUMAN
- P03989-1B27_HUMAN
- P10319-1B58_HUMAN
- P18463-1B37_HUMAN
- P18464-1B51_HUMAN
- P18465-1B57_HUMAN
- P30460-1B08_HUMAN
- P30461-1B13_HUMAN
- P30462-1B14_HUMAN
- P30464-1B15_HUMAN
- P30466-1B18_HUMAN
- P30475-1B39_HUMAN
- P30479-1B41_HUMAN
- P30480-1B42_HUMAN
- P30481-1B44_HUMAN
- P30483-1B45_HUMAN
- P30484-1B46_HUMAN
- P30485-1B47_HUMAN
- P30486-1B48_HUMAN
- P30487-1B49_HUMAN
- P30488-1B50_HUMAN
- P30490-1B52_HUMAN
- P30491-1B53_HUMAN
- P30492-1B54_HUMAN
- P30493-1B55_HUMAN
- P30495-1B56_HUMAN
- P30498-1B78_HUMAN
- P30685-1B35_HUMAN
- Q04826-1B40_HUMAN
- Q29718-1B82_HUMAN
- Q29836-1B67_HUMAN
- Q29940-1B59_HUMAN
- Q31610-1B81_HUMAN
- Q31612-1B73_HUMAN
- Q95365-1B38_HUMAN
- Glycosylation at posLast=110110
- Glycosylation at isoforms=110
Other Protein References for HLA-B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HLA-B
-
Abcam antibodies for HLA-B
-
Cloud-Clone Corp. Antibodies for HLA-B
- Invitrogen Antibodies for HLA-B
- antibodies-online: Search results for 126 available HLA-B Antibodies ranked by validation data
- Compare Top HLA-B Antibodies
-
Recommended
- 1 ICC Antibody (anti-human)
- 2 CyTox Antibodies (anti-human)
- 19 IF Antibodies (anti-human)
- 20 FACS Antibodies (anti-human)
- 74 WB Antibodies (anti-human)
- 2 FACS Antibodies (anti-monkey)
- 1 ICC Antibody (anti-human)
- 2 CyTox Antibodies (anti-human)
- 19 IF Antibodies (anti-human)
- 20 FACS Antibodies (anti-human)
- 74 WB Antibodies (anti-human)
- 2 FACS Antibodies (anti-monkey)
- GeneTex HLA-B antibody for HLA-B
-
Santa Cruz Biotechnology (SCBT) Antibodies for HLA-B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for HLA-B
- Origene Custom Protein Services for HLA-B
- Novus Biologicals lysates for HLA-B
-
Cloud-Clone Corp. Proteins for HLA-B
- Search GeneTex for Proteins for HLA-B
Assay Products
-
Cloud-Clone Corp. Assay Kits for HLA-B
No data available for DME Specific Peptides for HLA-B Gene
Domains & Families for HLA-B Gene
Gene Families for HLA-B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for HLA-B Gene
Suggested Antigen Peptide Sequences for HLA-B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P01889- Family:
-
- Belongs to the MHC class I family.
Function for HLA-B Gene
Molecular function for HLA-B Gene
- GENATLAS Biochemistry:
- HLA-B,beta chain,44kDa,class Ia (see MHC1)
- UniProtKB/Swiss-Prot Function:
-
Involved in the presentation of foreign antigens to the immune system.
- 1B07_HUMAN,P01889
- 1B08_HUMAN,P30460
- 1B13_HUMAN,P30461
- 1B14_HUMAN,P30462
- 1B15_HUMAN,P30464
- 1B18_HUMAN,P30466
- 1B27_HUMAN,P03989
- 1B35_HUMAN,P30685
- 1B37_HUMAN,P18463
- 1B38_HUMAN,Q95365
- 1B39_HUMAN,P30475
- 1B40_HUMAN,Q04826
- 1B41_HUMAN,P30479
- 1B42_HUMAN,P30480
- 1B44_HUMAN,P30481
- 1B45_HUMAN,P30483
- 1B46_HUMAN,P30484
- 1B47_HUMAN,P30485
- 1B48_HUMAN,P30486
- 1B49_HUMAN,P30487
- 1B50_HUMAN,P30488
- 1B51_HUMAN,P18464
- 1B52_HUMAN,P30490
- 1B53_HUMAN,P30491
- 1B54_HUMAN,P30492
- 1B55_HUMAN,P30493
- 1B56_HUMAN,P30495
- 1B57_HUMAN,P18465
- 1B58_HUMAN,P10319
- 1B59_HUMAN,Q29940
- 1B67_HUMAN,Q29836
- 1B73_HUMAN,Q31612
- 1B78_HUMAN,P30498
- 1B81_HUMAN,Q31610
- 1B82_HUMAN,Q29718
Phenotypes From GWAS Catalog for HLA-B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | receptor binding | IBA | -- |
| GO:0005515 | protein binding | IPI | 18322206 |
| GO:0042605 | peptide antigen binding | ISS,IBA | -- |
Phenotypes for HLA-B Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for HLA-B
-
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-B gene
- Search ViGene Biosciences for HLA-B
CRISPR Products
- Browse CRISPR knockouts for HLA-B
- genomics-online: gRNA clones - Search results for 45 available HLA-B gene related products
- Overview of 45 available HLA-B gene related products
-
Recommended
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- Applied Biological Materials CRISPR for HLA-B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HLA-B
- GenScript: Design CRISPR guide RNA sequences for HLA-B
miRNA for HLA-B Gene
- miRTarBase miRNAs that target HLA-B
-
- hsa-mir-615-3p (MIRT039965)
- hsa-mir-3653-3p (MIRT392124)
- hsa-mir-30e-3p (MIRT486949)
- hsa-mir-30d-3p (MIRT486950)
- hsa-mir-30a-3p (MIRT486951)
- hsa-mir-5047 (MIRT486952)
- hsa-mir-1301-3p (MIRT486953)
- hsa-mir-7156-3p (MIRT486954)
- hsa-mir-222-5p (MIRT486955)
- hsa-mir-4660 (MIRT486956)
- hsa-mir-548ax (MIRT486957)
- hsa-mir-548ao-5p (MIRT486958)
- hsa-mir-3129-5p (MIRT486959)
- hsa-mir-199b-3p (MIRT486960)
- hsa-mir-199a-3p (MIRT486961)
- hsa-mir-936 (MIRT486962)
- hsa-mir-10b-3p (MIRT486963)
- hsa-mir-9500 (MIRT486964)
- hsa-mir-6822-5p (MIRT486965)
- hsa-mir-5584-5p (MIRT486966)
- hsa-mir-6750-5p (MIRT486967)
- hsa-mir-495-5p (MIRT486968)
- hsa-mir-6818-3p (MIRT716680)
- hsa-mir-3620-5p (MIRT716681)
- hsa-mir-1587 (MIRT716682)
- hsa-mir-4417 (MIRT716683)
- hsa-mir-593-3p (MIRT716684)
- hsa-mir-6895-3p (MIRT716685)
- hsa-mir-654-5p (MIRT716686)
- hsa-mir-541-3p (MIRT716687)
- hsa-mir-6766-5p (MIRT716688)
- hsa-mir-6756-5p (MIRT716689)
- hsa-mir-4741 (MIRT716690)
- hsa-mir-4675 (MIRT716691)
- hsa-mir-762 (MIRT716692)
- hsa-mir-5001-5p (MIRT716693)
- hsa-mir-4498 (MIRT716694)
- hsa-mir-4492 (MIRT716695)
- hsa-mir-6829-5p (MIRT716696)
- hsa-mir-4656 (MIRT716697)
- hsa-mir-6876-3p (MIRT716698)
- hsa-mir-626 (MIRT716699)
- hsa-mir-6845-3p (MIRT716700)
- hsa-mir-1306-5p (MIRT716701)
miRNA Products
- Search ViGene Biosciences for HLA-B
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for 45 available HLA-B gene related products
- Overview of 45 available HLA-B gene related products
-
Recommended
- pPB-His-MBP
- pPB-C-His
- pPB-N-His
- pUC19
- pPM-C-His
- pPM-C-HA
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pPM-N-D-C-HA
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-B gene
Clone Products
- Sino Biological Human cDNA Clone for HLA-B
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for HLA-B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HLA-B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 45 available HLA-B gene related products
- Overview of 45 available HLA-B gene related products
-
Recommended
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- orf clones - Search results for 45 available HLA-B gene related products
- Overview of 45 available HLA-B gene related products
-
Recommended
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pPM-N-D-C-HA
- pPM-C-HA
- pPM-C-His
- pUC19
- pPB-N-His
- pPB-C-His
- pPB-His-MBP
- pPB-His-GST
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pCMV6-AC-GFP
- pCMV6-Entry
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- Applied Biological Materials Clones for HLA-B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for HLA-B
-
ViGene Biosciences adenoviral particle packaged cDNA for HLA-B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for HLA-B gene
- Search ViGene Biosciences for HLA-B
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for HLA-B Gene
Localization for HLA-B Gene
Subcellular locations from UniProtKB/Swiss-Prot for HLA-B Gene
- Membrane; Single-pass type I membrane protein.
-
- P01889-1B07_HUMAN
- P03989-1B27_HUMAN
- P10319-1B58_HUMAN
- P18463-1B37_HUMAN
- P18464-1B51_HUMAN
- P18465-1B57_HUMAN
- P30460-1B08_HUMAN
- P30461-1B13_HUMAN
- P30462-1B14_HUMAN
- P30464-1B15_HUMAN
- P30466-1B18_HUMAN
- P30475-1B39_HUMAN
- P30479-1B41_HUMAN
- P30480-1B42_HUMAN
- P30481-1B44_HUMAN
- P30483-1B45_HUMAN
- P30484-1B46_HUMAN
- P30485-1B47_HUMAN
- P30486-1B48_HUMAN
- P30487-1B49_HUMAN
- P30488-1B50_HUMAN
- P30490-1B52_HUMAN
- P30491-1B53_HUMAN
- P30492-1B54_HUMAN
- P30493-1B55_HUMAN
- P30495-1B56_HUMAN
- P30498-1B78_HUMAN
- P30685-1B35_HUMAN
- Q04826-1B40_HUMAN
- Q29718-1B82_HUMAN
- Q29836-1B67_HUMAN
- Q29940-1B59_HUMAN
- Q31610-1B81_HUMAN
- Q31612-1B73_HUMAN
- Q95365-1B38_HUMAN
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| endoplasmic reticulum | 5 |
| golgi apparatus | 5 |
| endosome | 4 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| cytosol | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005783 | endoplasmic reticulum | ISS | -- |
| GO:0005794 | Golgi apparatus | ISS | -- |
| GO:0005886 | plasma membrane | TAS,IBA | -- |
| GO:0005887 | integral component of plasma membrane | NAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for HLA-B Gene
Pathways & Interactions for HLA-B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Allograft rejection | ||
| 2 | Antigen processing-Cross presentation | ||
| 3 | Innate Immune System |
.61
|
|
| 4 | Immune response Role of DAP12 receptors in NK cells | ||
| 5 | Class I MHC mediated antigen processing and presentation | ||
Pathways by source for HLA-B Gene
3 BioSystems pathways for HLA-B Gene
15 Reactome pathways for HLA-B Gene
17 KEGG pathways for HLA-B Gene
2 GeneGo (Thomson Reuters) pathways for HLA-B Gene
2 Qiagen pathways for HLA-B Gene
Interacting Proteins for HLA-B Gene
Selected Interacting proteins:
ENSP00000399168
P30461-1B13_HUMAN
P30480-1B42_HUMAN
P01889-1B07_HUMAN
P30466-1B18_HUMAN
P30481-1B44_HUMAN
P30460-1B08_HUMAN
P03989-1B27_HUMAN
P30483-1B45_HUMAN
Q31612-1B73_HUMAN
P18464-1B51_HUMAN
P30493-1B55_HUMAN
P18463-1B37_HUMAN
P30462-1B14_HUMAN
P30492-1B54_HUMAN
P30491-1B53_HUMAN
P30484-1B46_HUMAN
P10319-1B58_HUMAN
P30498-1B78_HUMAN
P30685-1B35_HUMAN
Q29940-1B59_HUMAN
P30464-1B15_HUMAN
Q31610-1B81_HUMAN
Q29836-1B67_HUMAN
Q95365-1B38_HUMAN
Q04826-1B40_HUMAN
Q29718-1B82_HUMAN
P30475-1B39_HUMAN
P18465-1B57_HUMAN
P30485-1B47_HUMAN
P30486-1B48_HUMAN
P30495-1B56_HUMAN
P30488-1B50_HUMAN
P30487-1B49_HUMAN
P30490-1B52_HUMAN
P30479-1B41_HUMAN
for HLA-B Gene via
STRING
MINT
IID
UniProtKB