Aliases for HINFP Gene
External Ids for HINFP Gene
Previous HGNC Symbols for HINFP Gene
Previous GeneCards Identifiers for HINFP Gene
This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011]
GeneCards Summary for HINFP Gene
HINFP (Histone H4 Transcription Factor) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and enzyme binding.
UniProtKB/Swiss-Prot Summary for HINFP Gene
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.