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HHIPL2 (HHIP Like 2) is a Protein Coding gene. Diseases associated with HHIPL2 include Breast Apocrine Carcinoma and Mowat-Wilson Syndrome. Gene Ontology (GO) annotations related to this gene include quinone binding and oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor. An important paralog of this gene is HHIPL1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003824 | catalytic activity | IEA | -- |
GO:0005515 | protein binding | IPI | 25416956 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | ||||||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | HHIPL2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | HHIPL2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Hhipl2 30 |
|
||
Dog (Canis familiaris) |
Mammalia | HHIPL2 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Hhipl2 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | HHIPL2 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | HHIPL2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | HHIPL2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | hhipl2 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | tthu-A-prov 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC560376 30 |
|
||
HHIPL2 31 |
|
OneToOne | |||
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G39970 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
709036 | Benign: not provided | 222,544,020(-) | T/TC | FRAMESHIFT_VARIANT | |
716062 | Benign: not provided | 222,522,729(-) | C/CA | FRAMESHIFT_VARIANT | |
720660 | Benign: not provided | 222,538,766(-) | G/T | MISSENSE_VARIANT | |
728848 | Benign: not provided | 222,543,922(-) | C/T | MISSENSE_VARIANT | |
776341 | Benign: not provided | 222,522,679(-) | C/T | SYNONYMOUS_VARIANT |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2762168 | CNV | loss | 21179565 |
nsv1160091 | CNV | duplication | 26073780 |
Disorder | Aliases | PubMed IDs |
---|---|---|
breast apocrine carcinoma |
|
|
mowat-wilson syndrome |
|
|