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Aliases for HGH1 Gene

Aliases for HGH1 Gene

  • HGH1 Homolog 2 3 5
  • Family With Sequence Similarity 203, Member A 2 3
  • Family With Sequence Similarity 203, Member B 2 3
  • Brain Protein 16 2 3
  • C8orf30A 3 4
  • C8orf30B 3 4
  • FAM203A 3 4
  • FAM203B 3 4
  • Chromosome 8 Open Reading Frame 30A 2
  • Chromosome 8 Open Reading Frame 30B 2
  • HGH1 Homolog (S. Cerevisiae) 2
  • Brain Protein 16-Like 3
  • Protein HGH1 Homolog 3
  • Protein FAM203A 3
  • Protein FAM203B 3
  • BRP16L 3
  • BRP16 3

External Ids for HGH1 Gene

Previous HGNC Symbols for HGH1 Gene

  • C8orf30A
  • FAM203B
  • C8orf30B
  • FAM203A

Summaries for HGH1 Gene

GeneCards Summary for HGH1 Gene

HGH1 (HGH1 Homolog) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.

Additional gene information for HGH1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HGH1 Gene

Genomics for HGH1 Gene

GeneHancer (GH) Regulatory Elements for HGH1 Gene

Promoters and enhancers for HGH1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J144137 Promoter 1 EPDnew Ensembl 650.7 +0.1 132 1.4 HGH1 PIR34562 GC08P144119
GH08J144796 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 10 +661.2 661214 5 ARID4B SIN3A DMAP1 ZBTB7B YY1 POLR2B ZNF207 ZNF143 ZNF263 SP3 ZNF517 ZNF7 VPS28 CPSF1 RPL8 ZNF250 LRRC14 ZNF251 GPAA1 ADCK5
GH08J144101 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.2 -33.9 -33858 4 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 SP3 NFYC SHARPIN MAF1 ZNF623 ZNF7 ZNF16 ZNF251 ZNF250 ZNF517 CPSF1 ZNF696
GH08J143453 Enhancer 1.4 Ensembl ENCODE dbSUPER 10 -683.2 -683246 1.5 PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 E2F8 FOS ZNF592 MEF2D ZNF623 JRK TIGD5 CPSF1 VPS28 GPAA1 ENSG00000255050 SLC52A2 ZNF707 ZNF696
GH08J144412 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 5.5 +278.5 278463 7.3 HDGF PKNOX1 CLOCK MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B SLC39A4 VPS28 CPSF1 TONSL C8orf82 ENSG00000255182 HGH1 ZNF252P ENSG00000272115 GC08P144288
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HGH1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for HGH1 Gene

Genomic Locations for HGH1 Gene
3,075 bases
Plus strand
3,075 bases
Plus strand

Genomic View for HGH1 Gene

Genes around HGH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HGH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HGH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HGH1 Gene

Proteins for HGH1 Gene

  • Protein details for HGH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein HGH1 homolog
    Protein Accession:
    Secondary Accessions:
    • P0CB43

    Protein attributes for HGH1 Gene

    390 amino acids
    Molecular mass:
    42129 Da
    Quaternary structure:
    No Data Available

neXtProt entry for HGH1 Gene

Post-translational modifications for HGH1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for HGH1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for HGH1 Gene

Domains & Families for HGH1 Gene

Gene Families for HGH1 Gene

Protein Domains for HGH1 Gene

Suggested Antigen Peptide Sequences for HGH1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the HGH1 family.
  • Belongs to the HGH1 family.
genes like me logo Genes that share domains with HGH1: view

Function for HGH1 Gene

Phenotypes From GWAS Catalog for HGH1 Gene

Gene Ontology (GO) - Molecular Function for HGH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005488 binding IEA --
genes like me logo Genes that share ontologies with HGH1: view
genes like me logo Genes that share phenotypes with HGH1: view

Animal Model Products

miRNA for HGH1 Gene

miRTarBase miRNAs that target HGH1

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HGH1 Gene

Localization for HGH1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for HGH1 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for HGH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with HGH1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for HGH1 Gene

Pathways & Interactions for HGH1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for HGH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with HGH1: view

No data available for Pathways by source and SIGNOR curated interactions for HGH1 Gene

Drugs & Compounds for HGH1 Gene

No Compound Related Data Available

Transcripts for HGH1 Gene

mRNA/cDNA for HGH1 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HGH1 Gene

No ASD Table

Relevant External Links for HGH1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HGH1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HGH1 Gene

Protein differential expression in normal tissues from HIPED for HGH1 Gene

This gene is overexpressed in Bone (45.7) and Pancreas (16.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HGH1 Gene

Protein tissue co-expression partners for HGH1 Gene

NURSA nuclear receptor signaling pathways regulating expression of HGH1 Gene:

genes like me logo Genes that share expression patterns with HGH1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HGH1 Gene

Orthologs for HGH1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for HGH1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM203A 33
  • 99.11 (n)
-- 34
  • 98 (a)
(Canis familiaris)
Mammalia LOC609695 33
  • 84.17 (n)
-- 34
  • 80 (a)
(Bos Taurus)
Mammalia FAM203A 33
  • 84.13 (n)
-- 34
  • 82 (a)
(Mus musculus)
Mammalia Fam203a 34 33
  • 80.83 (n)
Hgh1 16
(Rattus norvegicus)
Mammalia Fam203a 33
  • 79.11 (n)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 61 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 54 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam203a 33
  • 60.79 (n)
Str.15925 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.22740 33
(Danio rerio)
Actinopterygii fam203a 34 33
  • 57.65 (n)
CABZ01049059.1 34
  • 41 (a)
Dr.16793 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3530 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001442 33
  • 51.04 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG6073 34 33
  • 48.27 (n)
(Caenorhabditis elegans)
Secernentea Y54H5A.2 34
  • 22 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AAL150W 33
  • 45.79 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F15433g 33
  • 43.59 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HGH1 34 33
  • 40.71 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G14300 33
  • 45.86 (n)
(Oryza sativa)
Liliopsida Os10g0406800 33
  • 41.89 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU08324 33
  • 48.78 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC26F1.12c 33
  • 46.38 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 41 (a)
Species where no ortholog for HGH1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for HGH1 Gene

Gene Tree for HGH1 (if available)
Gene Tree for HGH1 (if available)
Evolutionary constrained regions (ECRs) for HGH1: view image

Paralogs for HGH1 Gene

No data available for Paralogs for HGH1 Gene

Variants for HGH1 Gene

Sequence variations from dbSNP and Humsavar for HGH1 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000132029 -- 144,140,959(+) G/A downstream_transcript_variant
rs1000484401 -- 144,141,173(+) C/T downstream_transcript_variant
rs1001083812 -- 144,140,145(+) C/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1001523380 -- 144,136,612(+) G/C upstream_transcript_variant
rs1001536813 -- 144,139,950(+) C/T 3_prime_UTR_variant, genic_downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for HGH1 Gene

Variant ID Type Subtype PubMed ID
dgv12431n54 CNV loss 21841781
dgv906n27 CNV loss 19166990
esv2759651 CNV gain 17122850
esv29971 CNV loss 17803354
nsv1025071 CNV gain 25217958
nsv1030888 CNV gain 25217958
nsv1075598 CNV deletion 25765185
nsv1119194 CNV deletion 24896259
nsv1122205 CNV deletion 24896259
nsv1145205 CNV deletion 24896259
nsv428208 CNV gain 18775914
nsv466014 CNV loss 19166990
nsv470249 CNV loss 18288195
nsv515809 CNV gain+loss 19592680
nsv612915 CNV loss 21841781
nsv824802 CNV gain 20364138
nsv824803 CNV gain 20364138
nsv8395 CNV gain+loss 18304495
nsv950016 CNV deletion 24416366

Variation tolerance for HGH1 Gene

Gene Damage Index Score: 0.13; 2.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for HGH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HGH1 Gene

Disorders for HGH1 Gene

Additional Disease Information for HGH1

No disorders were found for HGH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HGH1 Gene

Publications for HGH1 Gene

  1. N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P … Aldabe R (Proceedings of the National Academy of Sciences of the United States of America 2012) 3 4 58
  2. Initial characterization of the human central proteome. (PMID: 21269460) Burkard TR … Colinge J (BMC systems biology 2011) 3 4 58
  3. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen JV … Mann M (Science signaling 2010) 3 4 58
  4. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S … Mohammed S (Analytical chemistry 2009) 3 4 58
  5. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N … Gygi SP (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 4 58

Products for HGH1 Gene

Sources for HGH1 Gene

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