Aliases for HEYL Gene
Aliases for HEYL Gene
External Ids for HEYL Gene
- HGNC: 4882
- Entrez Gene: 26508
- Ensembl: ENSG00000163909
- OMIM: 609034
- UniProtKB: Q9NQ87
Previous GeneCards Identifiers for HEYL Gene
- GC01M040119
- GC01M039093
- GC01M039553
- GC01M039503
- GC01M039492
- GC01M039741
- GC01M039862
- GC01M038207
Summaries for HEYL Gene
-
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for HEYL Gene
HEYL (Hes Related Family BHLH Transcription Factor With YRPW Motif-Like) is a Protein Coding gene. Diseases associated with HEYL include Cerebellopontine Angle Meningioma and Cerebellopontine Angle Tumor. Among its related pathways are HIV Life Cycle and Gastric cancer. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is HEY2.
UniProtKB/Swiss-Prot for HEYL Gene
-
Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5-CACGTG-3 (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HEYL Gene
Genomics for HEYL Gene
GeneHancer (GH) Regulatory Elements for HEYL Gene
Promoters and enhancers for HEYL Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around HEYL on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the HEYL gene promoter:
-
- AREB6
- SRF (504 AA)
- SRF
- E47
- Tal-1
- CREB
- deltaCREB
- LCR-F1
- Tal-1beta
Regulatory Element Products
Genomic Locations for HEYL Gene
Genomic Locations for HEYL Gene
- chr1:39,623,431-39,639,945
- (GRCh38/hg38)
- Size:
- 16,515 bases
- Orientation:
- Minus strand
- chr1:40,089,103-40,105,617
- (GRCh37/hg19)
- Size:
- 16,515 bases
- Orientation:
- Minus strand
Genomic View for HEYL Gene
Genes around HEYL on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.2 by Entrez Gene
- 1p34.2 by HGNC
- 1p34.2 by Ensembl
HEYL Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HEYL Gene
Proteins for HEYL Gene
-
Protein details for HEYL Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NQ87-HEYL_HUMAN
- Recommended name:
- Hairy/enhancer-of-split related with YRPW motif-like protein
- Protein Accession:
- Q9NQ87
- Q5TG99
Protein attributes for HEYL Gene
- Size:
- 328 amino acids
- Molecular mass:
- 35087 Da
- Quaternary structure:
-
- Self-associates. Interacts with GATA4, GATA6, HES1, HEY1 and HEY2. Interacts with HDAC1, NCOR1 and SIN3A.
Protein Expression for HEYL Gene
Post-translational modifications for HEYL Gene
Other Protein References for HEYL Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HEYL
-
Abcam antibodies for HEYL
- Invitrogen Antibodies for HEYL (AFLGC-HEYL)
- GeneTex HEYL Antibody for HEYL
-
Boster Bio Antibodies for HEYL
-
Santa Cruz Biotechnology (SCBT) Antibodies for HEYL
Protein Products
-
OriGene Purified Proteins for HEYL
- Search Origene for MassSpec and Protein Over-expression Lysates for HEYL
- Origene Custom Protein Services for HEYL
- Search GeneTex for Proteins for HEYL
Assay Products
- antibodies-online: Search results for 1 available HEYL Elisa Kits ranked by validation data
- Compare Top HEYL Elisa Kits
-
Recommended
No data available for DME Specific Peptides for HEYL Gene
Domains & Families for HEYL Gene
Gene Families for HEYL Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for HEYL Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for HEYL Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NQ87- Family:
-
- Belongs to the HEY family.
Function for HEYL Gene
Molecular function for HEYL Gene
- UniProtKB/Swiss-Prot Function:
- Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5-CACGTG-3 (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
- UniProtKB/Swiss-Prot Induction:
- By activation of the Notch signaling pathway.
Phenotypes From GWAS Catalog for HEYL Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | IEA | -- |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | NAS | 19274049 |
| GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | ISS,IEA | -- |
| GO:0000989 | transcription factor activity, transcription factor binding | IDA | 21290414 |
| GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | -- |
Phenotypes for HEYL Gene
- MGI mutant phenotypes for HEYL:
- inferred from 5 alleles
- GenomeRNAi human phenotypes for HEYL:
Animal Models for HEYL Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for HEYL
-
CRISPR Products
-
OriGene CRISPR knockouts for HEYL
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- genomics-online: gRNA clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- Applied Biological Materials CRISPR for HEYL
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HEYL
- GenScript: Design CRISPR guide RNA sequences for HEYL
miRNA for HEYL Gene
- miRTarBase miRNAs that target HEYL
-
- hsa-mir-93-3p (MIRT038777)
- hsa-mir-765 (MIRT475701)
- hsa-mir-6081 (MIRT475702)
- hsa-mir-4722-5p (MIRT475703)
- hsa-mir-4726-3p (MIRT475704)
- hsa-mir-6764-5p (MIRT475705)
- hsa-mir-1915-3p (MIRT475706)
- hsa-mir-6840-3p (MIRT475707)
- hsa-mir-4768-3p (MIRT475708)
- hsa-mir-761 (MIRT475709)
- hsa-mir-3619-5p (MIRT475710)
- hsa-mir-214-3p (MIRT475711)
- hsa-mir-4733-5p (MIRT475712)
- hsa-mir-6838-5p (MIRT475713)
- hsa-mir-6165 (MIRT475714)
- hsa-mir-497-5p (MIRT475715)
- hsa-mir-424-5p (MIRT475716)
- hsa-mir-195-5p (MIRT475717)
- hsa-mir-16-5p (MIRT475718)
- hsa-mir-15b-5p (MIRT475719)
- hsa-mir-15a-5p (MIRT475720)
- hsa-mir-4291 (MIRT495074)
- hsa-mir-668-5p (MIRT495075)
- hsa-mir-6787-3p (MIRT495076)
- hsa-mir-339-3p (MIRT495077)
- hsa-mir-5685 (MIRT495078)
- hsa-mir-4690-3p (MIRT495079)
- hsa-mir-922 (MIRT495080)
- hsa-mir-665 (MIRT544152)
- hsa-mir-1273e (MIRT544153)
- hsa-mir-6716-5p (MIRT544154)
- hsa-mir-4763-3p (MIRT544155)
- hsa-mir-1207-5p (MIRT544156)
- hsa-mir-7160-5p (MIRT544157)
- hsa-mir-6722-3p (MIRT544158)
- hsa-mir-1909-3p (MIRT544159)
- hsa-mir-6884-5p (MIRT544160)
- hsa-mir-485-5p (MIRT544161)
- hsa-mir-1827 (MIRT544162)
- hsa-mir-4649-3p (MIRT544163)
- hsa-mir-135b-5p (MIRT544164)
- hsa-mir-135a-5p (MIRT544165)
- hsa-mir-6783-5p (MIRT544166)
- hsa-mir-4478 (MIRT544167)
- hsa-mir-4419b (MIRT544168)
- hsa-mir-3929 (MIRT544169)
- hsa-mir-940 (MIRT544170)
- hsa-mir-6808-5p (MIRT544171)
- hsa-mir-6893-5p (MIRT544172)
- hsa-mir-2276-3p (MIRT623708)
- hsa-mir-7641 (MIRT640793)
- hsa-mir-4279 (MIRT640794)
- hsa-mir-642a-5p (MIRT640795)
- hsa-mir-4436b-5p (MIRT640796)
- hsa-mir-4695-3p (MIRT640797)
- hsa-mir-4469 (MIRT640798)
- hsa-mir-2276-5p (MIRT640799)
- hsa-mir-5092 (MIRT640800)
- hsa-mir-4638-5p (MIRT657446)
- hsa-mir-1307-3p (MIRT657447)
- hsa-mir-6741-3p (MIRT657448)
- hsa-mir-4693-5p (MIRT657449)
- hsa-mir-4699-3p (MIRT657450)
- hsa-mir-892c-3p (MIRT657451)
- hsa-mir-4676-3p (MIRT657452)
- hsa-mir-452-5p (MIRT657453)
- hsa-mir-6892-3p (MIRT657454)
- hsa-mir-24-3p (MIRT667960)
- hsa-mir-4284 (MIRT667961)
- hsa-mir-4772-3p (MIRT667962)
- hsa-mir-6880-3p (MIRT667963)
- hsa-mir-4485-5p (MIRT667964)
- hsa-mir-335-5p (MIRT667965)
- hsa-mir-5698 (MIRT671664)
- hsa-mir-6818-3p (MIRT671665)
- hsa-mir-143-5p (MIRT671666)
- hsa-mir-4430 (MIRT671667)
- hsa-mir-3652 (MIRT671668)
- hsa-mir-504-3p (MIRT671669)
- hsa-mir-3135b (MIRT671670)
- hsa-mir-6499-3p (MIRT671671)
- hsa-mir-3655 (MIRT671672)
- hsa-mir-1304-3p (MIRT671673)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HEYL
- Browse OriGene Inhibitory RNA Products For HEYL
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HEYL
- genomics-online: shRNA clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
Clone Products
- Sino Biological Human cDNA Clone for HEYL
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HEYL
- Applied Biological Materials Clones for HEYL
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
- ESI BIO PureStem ES-210, Ecto-ntu Progenitor for HEYL
-
Horizon Cell Lines for HEYL
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HEYL Gene
Localization for HEYL Gene
Subcellular locations from UniProtKB/Swiss-Prot for HEYL Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| mitochondrion | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
- Cytosol (2)
- Mitochondria (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 21454491 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA,ISS | -- |
Pathways & Interactions for HEYL Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by NOTCH1 | ||
| 2 | HIV Life Cycle |
.45
|
|
| 3 | Gastric cancer |
.62
|
|
| 4 | PI3K-Akt signaling pathway | ||
| 5 | Pathways in cancer | ||
Pathways by source for HEYL Gene
3 KEGG pathways for HEYL Gene
Interacting Proteins for HEYL Gene
Selected Interacting proteins:
Q9NQ87-HEYL_HUMAN
ENSP00000361943
for HEYL Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for HEYL
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0003151 | outflow tract morphogenesis | IEA,ISS | -- |
| GO:0003181 | atrioventricular valve morphogenesis | IEA,ISS | -- |
| GO:0003184 | pulmonary valve morphogenesis | IEA,ISS | -- |
| GO:0003198 | epithelial to mesenchymal transition involved in endocardial cushion formation | IEA,ISS | -- |
Transcripts for HEYL Gene
mRNA/cDNA for HEYL Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (139) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000372852 3661 bps (uc001cdp.4)
Unigene Clusters for HEYL Gene
CRISPR Products
-
OriGene CRISPR knockouts for HEYL
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HEYL
- genomics-online: gRNA clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- Applied Biological Materials CRISPR for HEYL
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HEYL
- GenScript: Design CRISPR guide RNA sequences for HEYL
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HEYL
- Browse OriGene Inhibitory RNA Products For HEYL
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HEYL
- genomics-online: shRNA clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
Clone Products
- Sino Biological Human cDNA Clone for HEYL
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HEYL
- Applied Biological Materials Clones for HEYL
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for HEYL Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Hair (Integumentary System)
- Fetal Matrix Cells Hair Follicle
- Fetal Inner Root Sheath Cells Inner Root Sheath
- Fetal Hair Shaft Cuticle Cells Hair Shaft
- Fetal Medulla Cells Hair Shaft
- Fetal Cortex Cells Hair Shaft
-
Epithelial Cells
- Fetal Matrix Cells Hair Follicle
- Fetal Inner Root Sheath Cells Inner Root Sheath
- Fetal Hair Shaft Cuticle Cells Hair Shaft
- Fetal Medulla Cells Hair Shaft
- Fetal Cortex Cells Hair Shaft
- Bone (Muscoskeletal System)
-
Kidney (Urinary System)
- Cortical Stroma Cells Interstitial Stroma
- Renal Vesicle
- Interstitial Stroma
- Metanephros
- Cartilage (Muscoskeletal System)
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
- Blood (Hematopoietic System)
- Neural Ectoderm (Nervous System)
mRNA differential expression in normal tissues according to GTEx for HEYL Gene
This gene is overexpressed in Artery - Coronary (x6.7), Artery - Tibial (x4.2), and Pancreas (x4.0).
This gene is overexpressed in Islet of Langerhans (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HEYL Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of HEYL Gene:
HEYLSOURCE GeneReport for Unigene cluster for HEYL Gene:
Hs.472566Evidence on tissue expression from TISSUES for HEYL Gene
- Muscle(4.4)
- Eye(2.6)
Primer Products
-
OriGene qPCR primer pairs for HEYL
-
OriGene qPCR primer pairs and template standards for HEYL
- genomics-online: primer clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HEYL Gene
Orthologs for HEYL Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HEYL 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HEYL 33 |
|
||
| cow (Bos Taurus) |
Mammalia | HEYL 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Heyl 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Heyl 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HEYL 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | HEYL 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HEYL 34 33 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | heyl 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Hey 34 35 |
|
OneToMany |
- Species where no ortholog for HEYL was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for HEYL Gene
- ENSEMBL:
- Gene Tree for HEYL (if available)
- TreeFam:
- Gene Tree for HEYL (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HEYL: view image
Paralogs for HEYL Gene
Variants for HEYL Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000031229 | -- | 39,634,341(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000139009 | -- | 39,641,668(-) | T/G | upstream_transcript_variant | |
| rs1000142660 | -- | 39,631,787(-) | A/T | intron_variant | |
| rs1000416735 | -- | 39,638,535(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000425551 | -- | 39,631,950(-) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3367103 | CNV | duplication | 20981092 |
| nsv1116447 | OTHER | inversion | 24896259 |
| nsv566 | CNV | insertion | 18451855 |
| nsv7177 | OTHER | inversion | 18451855 |
| nsv829649 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.64;
31.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HEYL Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HEYL Gene
Disorders for HEYL Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cerebellopontine angle meningioma |
|
|
| cerebellopontine angle tumor |
|
|
Search HEYL in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HEYL
No data available for UniProtKB/Swiss-Prot and Genatlas for HEYL Gene
Publications for HEYL Gene
- Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family. (PMID: 10860664) Steidl C … Gessler M (Genomics 2000) 2 3 4 22 58
- Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. (PMID: 15485867) Kathiriya IS … Nakagawa O (The Journal of biological chemistry 2004) 3 4 58
- Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes. (PMID: 10964718) Maier MM … Gessler M (Biochemical and biophysical research communications 2000) 3 4 58
- Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. (PMID: 11095750) Nakagawa O … Olson EN (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 4 58
- Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis. (PMID: 10415358) Leimeister C … Gessler M (Mechanisms of development 1999) 2 3 58
Products for HEYL Gene
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- Invitrogen Antibodies for HEYL (AFLGC-HEYL)
- Cyagen custom Knockout/knockin (KOKI) mouse models for HEYL
- antibodies-online: Search results for 53 available HEYL Antibodies ranked by validation data
- Compare Top HEYL Antibodies
- antibodies-online: Search results for 1 available HEYL Elisa Kits ranked by validation data
- Compare Top HEYL Elisa Kits
- Recommended
- antibodies-online: Search results for 6 available HEYL Proteins ranked by validation data
- Compare Top HEYL Proteins
- GeneTex HEYL Antibody for HEYL
- Search GeneTex for Proteins for HEYL
- Santa Cruz Biotechnology (SCBT) Antibodies for HEYL
- Search Santa Cruz Biotechnology (SCBT) for HEYL siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HEYL
- Horizon Cell Lines for HEYL
- genomics-online: cdna clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- orf clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- genomics-online: gRNA clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- genomics-online: primer clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- genomics-online: shRNA clones - Search results for 100 available HEYL gene related products
- Overview of 100 available HEYL gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HEYL
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HEYL
- GeneCopoeia miRNA 3'UTR Target clone products for HEYL
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HEYL
- Boster Bio Antibodies for HEYL
- Browse Boster Bio ELISA Kits
Sources for HEYL Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt