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Aliases for HES2 Gene
Aliases for HES2 Gene
External Ids for HES2 Gene
- HGNC: 16005
- NCBI Entrez Gene: 54626
- Ensembl: ENSG00000069812
- OMIM®: 609970
- UniProtKB/Swiss-Prot: Q9Y543
Previous GeneCards Identifiers for HES2 Gene
- GC01M006049
- GC01M006281
- GC01U900784
- GC01M006183
- GC01M006406
- GC01M005622
- GC01M006472
Summaries for HES2 Gene
GeneCards Summary for HES2 Gene
HES2 (Hes Family BHLH Transcription Factor 2) is a Protein Coding gene. Among its related pathways are Notch Signaling Pathway (sino) and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include transcription factor binding and double-stranded DNA binding. An important paralog of this gene is HES1.
UniProtKB/Swiss-Prot Summary for HES2 Gene
-
Transcriptional repressor of genes that require a bHLH protein for their transcription.
Additional gene information for HES2 Gene
- HGNC (16005)
- NCBI Entrez Gene (54626)
- Ensembl (ENSG00000069812)
- OMIM® (609970)
- UniProtKB/Swiss-Prot (Q9Y543)
- Open Targets Platform(ENSG00000069812)
- Search for HES2 at DataMed
- Search for HES2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HES2 Gene
Genomics for HES2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HES2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HES2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HES2
- Top Transcription factor binding sites by QIAGEN in the HES2 gene promoter:
-
- AhR
- AREB6
- Arnt
- c-Myc
- E47
- LCR-F1
- Max
- N-Myc
- Pax-4a
Genomic Locations for HES2 Gene
Latest Assembly
- chr1:6,412,418-6,424,670
- (GRCh38/hg38)
- Size:
- 12,253 bases
- Orientation:
- Minus strand
Previous Assembly
- chr1:6,475,292-6,479,979
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 4,688 bases
- Orientation:
- Minus strand
- chr1:6,472,478-6,484,730
- (GRCh37/hg19 by Ensembl)
- Size:
- 12,253 bases
- Orientation:
- Minus strand
Genomic View for HES2 Gene
Genes around HES2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.31 by HGNC
- 1p36.31 by Entrez Gene
- 1p36.31 by Ensembl
HES2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HES2 Gene
Proteins for HES2 Gene
-
Protein details for HES2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y543-HES2_HUMAN
- Recommended name:
- Transcription factor HES-2
- Protein Accession:
- Q9Y543
- A2RTZ9
- Q96EN4
- Q9Y542
Protein attributes for HES2 Gene
- Size:
- 173 amino acids
- Molecular mass:
- 18470 Da
- Quaternary structure:
-
- Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Protein Expression for HES2 Gene
Post-translational modifications for HES2 Gene
Other Protein References for HES2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ HES2 Antibody
- Novus Biologicals Antibodies for HES2
-
Abcam antibodies for HES2
- Invitrogen Antibodies for HES2 (AFLGC-HES2)
-
Boster Bio Antibodies for HES2
-
Santa Cruz Biotechnology (SCBT) Antibodies for HES2
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for HES2
- Origene Custom Protein Services for HES2
- Novus Biologicals proteins for HES2
- ProSpec Recombinant Proteins for HES2
- antibodies-online: Show 7 available HES2 Proteins ranked by validation data
- Compare Top HES2 Proteins
-
Quality Products:
-
Abcam proteins for HES2
Assay products for research
- antibodies-online: Search results for available HES2 related products ranked by validation data
No data available for DME Specific Peptides for HES2 Gene
Domains & Families for HES2 Gene
Gene Families for HES2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for HES2 Gene
- InterPro:
- Blocks:
-
- Basic helix-loop-helix dimerization domain bHLH
- Orange
- ProtoNet:
Suggested Antigen Peptide Sequences for HES2 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ33803 fis, clone CTONG2000561, highly similar to Transcription factor HES-2 (A2RTZ9_HUMAN)
- Hairy and enhancer of split 2 (HES2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y543UniProtKB/Swiss-Prot:
HES2_HUMAN :- Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
- Domain:
-
- Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
- The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
Function for HES2 Gene
Molecular function for HES2 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor of genes that require a bHLH protein for their transcription.
Phenotypes From GWAS Catalog for HES2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA,IBA | 21873635 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003690 | double-stranded DNA binding | IEA | -- |
Phenotypes for HES2 Gene
- GenomeRNAi human phenotypes for HES2:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Dynamic nuclei (hole, folded or small irregular)
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Increased Nanog expression
- Strongly decreased NFAT1-GFP nuclear translocation
- Decreased nuclei size in G2M
- Increased G2M DNA content
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for HES2 - Starting at $85 >
- * HES2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for HES2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HES2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HES2
miRNA for HES2 Gene
- miRTarBase miRNAs that target HES2
-
- hsa-miR-335-5p (MIRT018989)
- hsa-miR-1273e (MIRT449553)
- hsa-miR-509-3p (MIRT449554)
- hsa-miR-571 (MIRT449555)
- hsa-miR-5002-3p (MIRT449556)
- hsa-miR-219a-1-3p (MIRT449557)
- hsa-miR-4538 (MIRT449558)
- hsa-miR-4453 (MIRT449559)
- hsa-miR-552-5p (MIRT528065)
- hsa-miR-3074-5p (MIRT528066)
- hsa-miR-302d-5p (MIRT528067)
- hsa-miR-302b-5p (MIRT528068)
- hsa-miR-372-5p (MIRT528069)
- hsa-miR-6893-3p (MIRT528070)
- hsa-miR-370-3p (MIRT528071)
- hsa-miR-649 (MIRT528072)
- hsa-miR-490-3p (MIRT528073)
- mmu-miR-1933-3p (MIRT598683)
- hsa-miR-6848-3p (MIRT633562)
- hsa-miR-6843-3p (MIRT633563)
- hsa-miR-4454 (MIRT633564)
- hsa-miR-1224-3p (MIRT633565)
- hsa-miR-125a-3p (MIRT633566)
- hsa-miR-6813-3p (MIRT633567)
- hsa-miR-6783-3p (MIRT645118)
- hsa-miR-1343-3p (MIRT645119)
- hsa-miR-23b-5p (MIRT645120)
- hsa-miR-23a-5p (MIRT645121)
- hsa-miR-4772-3p (MIRT645122)
- hsa-miR-3920 (MIRT645123)
- hsa-miR-1304-3p (MIRT645124)
- hsa-miR-6742-3p (MIRT645125)
- hsa-miR-6852-5p (MIRT645126)
- hsa-miR-939-3p (MIRT645127)
- hsa-miR-660-3p (MIRT645128)
- hsa-miR-6890-3p (MIRT645129)
- hsa-miR-1306-5p (MIRT645130)
- hsa-miR-203b-3p (MIRT645131)
- hsa-miR-7158-3p (MIRT645132)
- hsa-miR-378a-5p (MIRT645133)
- hsa-miR-6821-3p (MIRT645134)
- hsa-miR-6790-3p (MIRT645135)
- hsa-miR-4680-5p (MIRT645136)
- hsa-miR-4635 (MIRT645137)
- hsa-miR-3653-5p (MIRT645138)
- hsa-miR-3934-5p (MIRT645139)
- hsa-miR-764 (MIRT645140)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HES2
- Browse OriGene Inhibitory RNA Products For HES2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HES2
Clone products for research
- Applied Biological Materials (abm): Clones for HES2 - Starting at $45 >
- * HES2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for HES2
- Addgene plasmids for HES2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HES2
Cell Lines for research
-
Horizon Cell Lines for HES2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for HES2 Gene
Localization for HES2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HES2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | ISA | -- |
| GO:0005634 | nucleus | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for HES2 Gene
Pathways & Interactions for HES2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | PI3K-Akt signaling pathway | ||
| 2 | Notch Signaling Pathway (sino) | ||
Pathways by source for HES2 Gene
1 Sino Biological pathway for HES2 Gene
1 KEGG pathway for HES2 Gene
Interacting Proteins for HES2 Gene
GPS-Prot Interaction Network for HES2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | 21873635 |
| GO:0009952 | anterior/posterior pattern specification | IBA | 21873635 |
| GO:0045892 | negative regulation of transcription, DNA-templated | IEA | -- |
No data available for SIGNOR curated interactions for HES2 Gene
Transcripts for HES2 Gene
mRNA/cDNA for HES2 Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000377834 4262 nts (view in UCSC)
- ENST00000377836 507 nts (view in UCSC)
- ENST00000377837 1222 nts (view in UCSC)
- ENST00000471190 349 nts (view in UCSC)
- ENST00000487437 968 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for HES2 - Starting at $85 >
- * HES2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for HES2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HES2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HES2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HES2
- Browse OriGene Inhibitory RNA Products For HES2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HES2
Clone products for research
- Applied Biological Materials (abm): Clones for HES2 - Starting at $45 >
- * HES2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for HES2
- Addgene plasmids for HES2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HES2
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||
| SP3: | |||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||
| SP6: | - | - | - | - | - |
Relevant External Links for HES2 Gene
- GeneLoc Exon Structure for
- HES2
Expression for HES2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for HES2 Gene
This gene is overexpressed in Esophagus - Mucosa (x13.1), Vagina (x8.2), Skin - Not Sun Exposed (Suprapubic) (x7.5), Skin - Sun Exposed (Lower leg) (x6.8), and Cervix - Ectocervix (x4.4).
This gene is overexpressed in Peripheral blood mononuclear cells (65.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HES2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HES2
SOURCE GeneReport for Unigene cluster for HES2 Gene:
Hs.118727mRNA Expression by UniProt/SwissProt for HES2 Gene:
Q9Y543-HES2_HUMAN
Tissue specificity:
Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.
Evidence on tissue expression from TISSUES for HES2 Gene
- Eye(4.1)
Primer products for research
-
OriGene qPCR primer pairs for HES2
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for HES2 Gene
Orthologs for HES2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HES2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | HES2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Hes2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Hes2 30 17 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | HES2 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | HES2 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | HES2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | hes2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | hes2.1 30 31 |
|
OneToMany | |
| hes2.2 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | h 31 |
|
ManyToMany | |
| Side 31 |
|
ManyToMany | |||
| dpn 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for HES2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for HES2 Gene
- ENSEMBL:
- Gene Tree for HES2 (if available)
- TreeFam:
- Gene Tree for HES2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HES2: view image
Paralogs for HES2 Gene
Variants for HES2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HES2 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs2235687 | - |
p.Pro139Ser |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Gene Damage Index Score:
3.36;
53.91% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HES2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HES2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HES2 Gene
Disorders for HES2 Gene
Additional Disease Information for HES2
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for HES2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HES2 Gene
Publications for HES2 Gene
- Identification and characterization of human HES2, HES3, and HES5 genes in silico. (PMID: 15254753) Katoh M … Katoh M (International journal of oncology 2004) 2 3 4 23
- Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. (PMID: 17611704) Katoh M … Katoh M (International journal of oncology 2007) 3 23
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for HES2 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for HES2
- Origene Custom Protein Services for HES2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HES2
- Browse OriGene Inhibitory RNA Products For HES2
- OriGene qPCR primer pairs for HES2
- OriGene CRISPR knockouts for HES2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HES2
- Sino Biological Human cDNA Clone for HES2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for HES2
- Novus Biologicals proteins for HES2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for HES2
- Abcam proteins for HES2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for HES2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for HES2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HES2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HES2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HES2
- Addgene plasmids for HES2
- antibodies-online: Show 6 available HES2 Antibodies ranked by validation data
- Compare Top HES2 Antibodies
- antibodies-online: Search results for available HES2 related products ranked by validation data
- antibodies-online: Show 7 available HES2 Proteins ranked by validation data
- Compare Top HES2 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for HES2
- Search Santa Cruz Biotechnology (SCBT) for HES2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HES2
- Horizon Cell Lines for HES2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HES2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HES2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HES2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HES2
- Boster Bio Antibodies for HES2
- Browse Boster Bio ELISA Kits
Sources for HES2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
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- (55) TGDB
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- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
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- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
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- (115) NCBI Bookshelf
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- (118) HPO
- (119) UDN
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- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
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- (130) CIViC
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- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB