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HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochr... See more...
Aliases for HERC6 Gene
Aliases for HERC6 Gene
External Ids for HERC6 Gene
- HGNC: 26072
- Entrez Gene: 55008
- Ensembl: ENSG00000138642
- OMIM: 609249
- UniProtKB: Q8IVU3
Previous GeneCards Identifiers for HERC6 Gene
- GC04U900413
- GC04P089603
- GC04P089518
- GC04P089299
- GC04P085051
Summaries for HERC6 Gene
-
HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
GeneCards Summary for HERC6 Gene
HERC6 (HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 6) is a Protein Coding gene. Diseases associated with HERC6 include Marburg Hemorrhagic Fever. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is HERC5.
UniProtKB/Swiss-Prot Summary for HERC6 Gene
-
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Additional gene information for HERC6 Gene
- HGNC(26072)
- Entrez Gene(55008)
- Ensembl(ENSG00000138642)
- OMIM(609249)
- UniProtKB(Q8IVU3)
- Open Targets Platform(ENSG00000138642)
- Monarch Initiative
- Search for HERC6 at DataMed
- Search for HERC6 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HERC6 Gene
Genomics for HERC6 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HERC6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HERC6 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HERC6
- Top Transcription factor binding sites by QIAGEN in the HERC6 gene promoter:
-
- AML1a
- AP-4
- NF-AT
- NF-AT1
- NF-AT2
- NF-AT3
- NF-AT4
- Nkx3-1 v2
- Nkx3-1 v3
- Nkx3-1 v4
Genomic Locations for HERC6 Gene
Genomic Locations for HERC6 Gene
- chr4:88,378,485-88,443,097
- (GRCh38/hg38)
- Size:
- 64,613 bases
- Orientation:
- Plus strand
- chr4:89,299,891-89,364,263
- (GRCh37/hg19)
- Size:
- 64,373 bases
- Orientation:
- Plus strand
Genomic View for HERC6 Gene
Genes around HERC6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q22.1 by HGNC
- 4q22.1 by Entrez Gene
- 4q22.1 by Ensembl
HERC6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HERC6 Gene
Proteins for HERC6 Gene
-
Protein details for HERC6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IVU3-HERC6_HUMAN
- Recommended name:
- Probable E3 ubiquitin-protein ligase HERC6
- Protein Accession:
- Q8IVU3
- B4DIY5
- Q5GC90
- Q5GRH3
- Q5HYM6
- Q5JPB6
- Q6PIF4
- Q8NAN3
- Q9NWS4
Protein attributes for HERC6 Gene
- Size:
- 1022 amino acids
- Molecular mass:
- 115126 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA91303.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC03879.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI46056.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI46151.1; Type=Erroneous initiation; Evidence={ECO:0000305};
- Miscellaneous:
-
- [Isoform 1]: Major transcript.
- [Isoform 2]: Minor transcript.
- [Isoform 3]: Minor transcript.
Protein Expression for HERC6 Gene
Selected DME Specific Peptides for HERC6 Gene
- Q8IVU3:
-
- QVAAGGAHSF
- YHSLALSK
- FPLALYKKLL
Post-translational modifications for HERC6 Gene
Other Protein References for HERC6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences HERC6 Antibody
-
Custom Antibody ServicesOriGene Antibodies for HERC6
- Novus Biologicals Antibodies for HERC6
-
Abcam antibodies for HERC6
- Invitrogen Antibodies for HERC6 (AFLGC-HERC6)
-
Biorbyt antibodies for HERC6
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for HERC6
- Origene Custom Protein Services for HERC6
- antibodies-online: Show 4 available HERC6 Proteins ranked by validation data
- Compare Top HERC6 Proteins
-
Quality Products:
-
Abcam proteins for HERC6
Assay Products
-
Signalway ELISA kits for HERC6
Domains & Families for HERC6 Gene
Gene Families for HERC6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for HERC6 Gene
- InterPro:
- Blocks:
-
- HECT domain (Ubiquitin-protein ligase)
- ProtoNet:
Suggested Antigen Peptide Sequences for HERC6 Gene
- GenScript: Design optimal peptide antigens:
-
- HECT domain and RCC1-like domain-containing protein 6 (HERC6_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for HERC6 Gene
Function for HERC6 Gene
Molecular function for HERC6 Gene
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.26;.
Enzyme Numbers (IUBMB) for HERC6 Gene
Phenotypes From GWAS Catalog for HERC6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for HERC6 Gene
- MGI mutant phenotypes for HERC6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for HERC6:
Animal Models for HERC6 Gene
- MGI Knock Outs for HERC6:
-
- Herc6 Herc6<tm1b(EUCOMM)Hmgu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HERC6 - Select products 50% OFF >
- * HERC6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HERC6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HERC6
-
Santa Cruz Biotechnology (SCBT) CRISPR for HERC6
miRNA for HERC6 Gene
- miRTarBase miRNAs that target HERC6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HERC6
- Browse OriGene Inhibitory RNA Products For HERC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HERC6
Clone Products
- Applied Biological Materials (abm): Clones for HERC6 - Select products 50% OFF >
- * HERC6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HERC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HERC6
Cell Line Products
-
Horizon Cell Lines for HERC6
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HERC6 Gene
Localization for HERC6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HERC6 Gene
- Cytoplasm, cytosol.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (3)
- Nucleoplasm (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for HERC6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for HERC6 Gene
4 Reactome pathways for HERC6 Gene
UniProtKB/Swiss-Prot Q8IVU3-HERC6_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for HERC6 Gene
GPS-Prot Interaction Network for HERC6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000209 | protein polyubiquitination | TAS | -- |
| GO:0002244 | hematopoietic progenitor cell differentiation | IEA | -- |
| GO:0009617 | response to bacterium | IEA | -- |
| GO:0016567 | protein ubiquitination | IEA | -- |
No data available for SIGNOR curated interactions for HERC6 Gene
Transcripts for HERC6 Gene
mRNA/cDNA for HERC6 Gene
- 5 REFSEQ mRNAs :
- 16 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000264346 3776 nts (view in UCSC)
- ENST00000273960 3473 nts (view in UCSC)
- ENST00000380265 3781 nts (view in UCSC)
- ENST00000502870 557 nts (view in UCSC)
- ENST00000504905 517 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for HERC6 - Select products 50% OFF >
- * HERC6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for HERC6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HERC6
-
Santa Cruz Biotechnology (SCBT) CRISPR for HERC6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HERC6
- Browse OriGene Inhibitory RNA Products For HERC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HERC6
Clone Products
- Applied Biological Materials (abm): Clones for HERC6 - Select products 50% OFF >
- * HERC6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for HERC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HERC6
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
| ExUns: | 20 | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||
| SP2: | - | - | |||||||||||||
| SP3: | - | - | |||||||||||||
| SP4: | - | - | |||||||||||||
| SP5: | |||||||||||||||
| SP6: | |||||||||||||||
| SP7: | |||||||||||||||
| SP8: |
Relevant External Links for HERC6 Gene
- GeneLoc Exon Structure for
- HERC6
Expression for HERC6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Germ Cells (Reproductive System)
- Gonad
-
Esophagus (Gastrointestinal Tract)
This gene is overexpressed in Fetal heart (17.8), Heart (12.4), Liver (11.6), Plasma (10.3), Monocytes (8.7), and Platelet (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HERC6 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HERC6
SOURCE GeneReport for Unigene cluster for HERC6 Gene:
Hs.529317mRNA Expression by UniProt/SwissProt for HERC6 Gene:
Q8IVU3-HERC6_HUMAN
Tissue specificity:
Detected in brain, heart, placenta and testis.
Evidence on tissue expression from TISSUES for HERC6 Gene
- Nervous system(4.4)
- Blood(4.3)
- Lymph node(4.3)
- Heart(4.3)
Primer Products
-
OriGene qPCR primer pairs for HERC6
-
OriGene qPCR primer pairs and template standards for HERC6
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for HERC6 Gene
Orthologs for HERC6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HERC6 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | HERC6 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | HERC6 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Herc6 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Herc6 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | HERC6 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | HERC6 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | herc6 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG6678 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | K11D2.1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for HERC6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Zebrafish (Danio rerio)
Evolution for HERC6 Gene
- ENSEMBL:
- Gene Tree for HERC6 (if available)
- TreeFam:
- Gene Tree for HERC6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HERC6: view image
Paralogs for HERC6 Gene
Paralogs for HERC6 Gene
(9) SIMAP similar genes for HERC6 Gene using alignment to 3 proteins:
- HERC6_HUMAN
- D6RCT4_HUMAN
- H0Y9U0_HUMAN
Variants for HERC6 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HERC6 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 709772 | Benign: not provided | 88,423,879(+) | G/A | MISSENSE_VARIANT | |
| 782443 | Benign: not provided | 88,424,608(+) | C/T | MISSENSE_VARIANT,INTRON_VARIANT | |
| 785099 | Benign: not provided | 88,436,931(+) | C/A | MISSENSE_VARIANT | |
| 785100 | Benign: not provided | 88,442,262(+) | T/C | SYNONYMOUS_VARIANT | |
| 785101 | Benign: not provided | 88,442,360(+) | C/A | MISSENSE_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3601302 | CNV | loss | 21293372 |
| esv3601304 | CNV | loss | 21293372 |
| nsv1073353 | CNV | deletion | 25765185 |
| nsv1074734 | CNV | deletion | 25765185 |
| nsv1136886 | CNV | deletion | 24896259 |
| nsv1142613 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
96.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.31;
81.41% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HERC6 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HERC6 Gene
Disorders for HERC6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| marburg hemorrhagic fever |
|
|
Search HERC6 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HERC6
No data available for UniProtKB/Swiss-Prot and Genatlas for HERC6 Gene
Publications for HERC6 Gene
- The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects. (PMID: 15676274) Hochrainer K … Kroismayr R (Genomics 2005) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. (PMID: 29643511) Pao KC … Virdee S (Nature 2018) 3
- The essential player in adipogenesis GRP78 is a novel KCTD15 interactor. (PMID: 29665387) Smaldone G … Pedone E (International journal of biological macromolecules 2018) 3
ExternalLinks
Products for HERC6 Gene
- Custom Antibody ServicesOriGene Antibodies for HERC6
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for HERC6
- Origene Custom Protein Services for HERC6
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HERC6
- Browse OriGene Inhibitory RNA Products For HERC6
- OriGene qPCR primer pairs for HERC6
- OriGene qPCR primer pairs and template standards for HERC6
- OriGene CRISPR knockouts for HERC6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HERC6
- Sino Biological Human cDNA Clone for HERC6
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for HERC6
- Novus Biologicals proteins and lysates for HERC6
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for HERC6
- Abcam proteins for HERC6
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for HERC6 (AFLGC-HERC6)
- VectorBuilder Custom and pre-made DNA vectors for HERC6 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for HERC6 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HERC6 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HERC6 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HERC6
- antibodies-online: Show 29 available HERC6 Antibodies ranked by validation data
- Compare Top HERC6 Antibodies
- antibodies-online: Search results for available HERC6 related products ranked by validation data
- antibodies-online: Show 4 available HERC6 Proteins ranked by validation data
- Compare Top HERC6 Proteins
- Quality Products:
- Horizon Cell Lines for HERC6
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HERC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HERC6
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HERC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HERC6
- Biorbyt antibodies for HERC6
- Signalway ELISA kits for HERC6
Sources for HERC6 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
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