Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012] See more...
Aliases for HERC3 Gene
Aliases for HERC3 Gene
External Ids for HERC3 Gene
- HGNC: 4876
- NCBI Entrez Gene: 8916
- Ensembl: ENSG00000287542
- OMIM®: 605200
- UniProtKB/Swiss-Prot: Q15034
Previous GeneCards Identifiers for HERC3 Gene
- GC04P089671
- GC04P089815
- GC04P089906
- GC04P089972
- GC04P089870
- GC04U900479
- GC04P089513
- GC04P085266
- GC04P089444
- GC04P088521
- GC04P088592
- GC04P088534
Summaries for HERC3 Gene
-
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
GeneCards Summary for HERC3 Gene
HERC3 (HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 3) is a Protein Coding gene. Diseases associated with HERC3 include Epidural Abscess. Among its related pathways are Ubiquitin mediated proteolysis and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is HERC4.
UniProtKB/Swiss-Prot Summary for HERC3 Gene
-
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Additional gene information for HERC3 Gene
- HGNC (4876)
- NCBI Entrez Gene (8916)
- Ensembl (ENSG00000287542)
- OMIM® (605200)
- UniProtKB/Swiss-Prot (Q15034)
- Search for HERC3 at DataMed
- Search for HERC3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HERC3 Gene
Genomics for HERC3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HERC3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HERC3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HERC3
- Top Transcription factor binding sites by QIAGEN in the HERC3 gene promoter:
-
- aMEF-2
- AREB6
- Brachyury
- FOXL1
- FOXO4
- MEF-2A
- p53
- Pax-4a
- POU3F2
- POU6F1 (c2)
Genomic Locations for HERC3 Gene
Latest Assembly
- chr4:88,523,810-88,709,303
- (GRCh38/hg38)
- Size:
- 185,494 bases
- Orientation:
- Plus strand
Previous Assembly
- chr4:89,444,994-89,629,690
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 184,697 bases
- Orientation:
- Plus strand
Genomic View for HERC3 Gene
Genes around HERC3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q22.1 by HGNC
- 4q22.1 by Entrez Gene
- 4q22.1 by Ensembl
HERC3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HERC3 Gene
Proteins for HERC3 Gene
-
Protein details for HERC3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15034-HERC3_HUMAN
- Recommended name:
- Probable E3 ubiquitin-protein ligase HERC3
- Protein Accession:
- Q15034
- A8K1S5
- Q8IXX3
Protein attributes for HERC3 Gene
- Size:
- 1050 amino acids
- Molecular mass:
- 117188 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA04945.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for HERC3 Gene
Selected DME Specific Peptides for HERC3 Gene
- Q15034:
-
- FLLFLTGSDRIPI
- NLLDLPKY
- QVAAGGAHSF
- GGVFTFGAG
- EETFCLNFTI
- NRQEFVDAYV
- FPLALYKKLL
Post-translational modifications for HERC3 Gene
- Ubiquitinated; which promotes degradation by the proteasome.
-
Ubiquitination at Lys63 and Lys920
- NX_Q15034 (NX_Q15034-1)
- Modification sites at PhosphoSitePlus
Other Protein References for HERC3 Gene
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for HERC3
- Novus Biologicals Antibodies for HERC3
-
Abcam antibodies for HERC3
- Invitrogen Antibodies for HERC3 (AFLGC-HERC3)
-
Boster Bio Antibodies for HERC3
-
Santa Cruz Biotechnology (SCBT) Antibodies for HERC3
Protein products for research
-
OriGene Purified Proteins for HERC3
- Search Origene for MassSpec and Protein Over-expression Lysates for HERC3
- Origene Custom Protein Services for HERC3
-
Abcam proteins for HERC3
Assay products for research
Domains & Families for HERC3 Gene
Gene Families for HERC3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for HERC3 Gene
- InterPro:
- Blocks:
-
- HECT domain (Ubiquitin-protein ligase)
- Regulator of chromosome condensation, RCC1
- ProtoNet:
Suggested Antigen Peptide Sequences for HERC3 Gene
- GenScript: Design optimal peptide antigens:
-
- HECT domain and RCC1-like domain-containing protein 3 (HERC3_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for HERC3 Gene
Function for HERC3 Gene
Molecular function for HERC3 Gene
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.26;.
Enzyme Numbers (IUBMB) for HERC3 Gene
Phenotypes From GWAS Catalog for HERC3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IEA | -- |
Phenotypes for HERC3 Gene
- MGI mutant phenotypes for HERC3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for HERC3:
Animal Models for HERC3 Gene
- MGI Knock Outs for HERC3:
-
- Herc3 Herc3<tm1a(EUCOMM)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for HERC3 - Starting at $85 >
- * HERC3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for HERC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HERC3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HERC3
miRNA for HERC3 Gene
- miRTarBase miRNAs that target HERC3
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HERC3
- Browse OriGene Inhibitory RNA Products For HERC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HERC3
Clone products for research
- Applied Biological Materials (abm): Clones for HERC3 - Starting at $45 >
- * HERC3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for HERC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HERC3
Cell Lines for research
-
Horizon Cell Lines for HERC3
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HERC3 Gene
Localization for HERC3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HERC3 Gene
- Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | IDA | -- |
| GO:0031410 | cytoplasmic vesicle | IEA | -- |
Pathways & Interactions for HERC3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Ubiquitin mediated proteolysis | ||
| 3 | Innate Immune System |
.61
|
|
Pathways by source for HERC3 Gene
4 Reactome pathways for HERC3 Gene
1 KEGG pathway for HERC3 Gene
UniProtKB/Swiss-Prot Q15034-HERC3_HUMAN
- Pathway: Protein modification; protein ubiquitination.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016567 | protein ubiquitination | IEA | -- |
No data available for SIGNOR curated interactions for HERC3 Gene
Transcripts for HERC3 Gene
mRNA/cDNA for HERC3 Gene
- 10 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000512194 4967 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for HERC3 - Starting at $85 >
- * HERC3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for HERC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HERC3
-
Santa Cruz Biotechnology (SCBT) CRISPR for HERC3
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HERC3
- Browse OriGene Inhibitory RNA Products For HERC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HERC3
Clone products for research
- Applied Biological Materials (abm): Clones for HERC3 - Starting at $45 >
- * HERC3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for HERC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HERC3
Relevant External Links for HERC3 Gene
- GeneLoc Exon Structure for
- HERC3
Expression for HERC3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
-
Eye (Sensory Organs)
- Mature Rod Cells Outer Nuclear Layer
-
Neurons
- Mature Rod Cells Outer Nuclear Layer
-
Limb (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
-
Bone (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
-
Cartilage (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
-
Thyroid (Endocrine System)
This gene is overexpressed in Urine (13.4), Platelet (13.3), Colon muscle (12.1), Plasma (10.6), and Stomach (8.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for HERC3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HERC3
SOURCE GeneReport for Unigene cluster for HERC3 Gene:
Hs.35804Evidence on tissue expression from TISSUES for HERC3 Gene
- Nervous system(4.8)
- Skin(4.3)
- Bone marrow(4.2)
Primer products for research
-
OriGene qPCR primer pairs for HERC3
-
OriGene qPCR primer pairs and template standards for HERC3
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for HERC3 Gene
Orthologs for HERC3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | HERC3 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | HERC3 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | HERC3 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Herc3 30 17 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | Herc3 30 |
|
||
| Chicken (Gallus gallus) |
Aves | HERC3 30 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | herc3 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | herc3 30 |
|
||
| Dr.16537 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7420 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9153 32 |
|
|
|
| Worm (Caenorhabditis elegans) |
Secernentea | herc-1 30 |
|
||
| Y48G8AL.1 32 |
|
|
- Species where no ortholog for HERC3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for HERC3 Gene
- ENSEMBL:
- Gene Tree for HERC3 (if available)
- TreeFam:
- Gene Tree for HERC3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HERC3: view image
Paralogs for HERC3 Gene
Paralogs for HERC3 Gene
(17) SIMAP similar genes for HERC3 Gene using alignment to 10 proteins:
- HERC3_HUMAN
- C9J6Z1_HUMAN
- C9J8E7_HUMAN
- C9JFL2_HUMAN
- C9JKA7_HUMAN
- D6RAT5_HUMAN
- F5GWU0_HUMAN
- H0Y8G9_HUMAN
- Q4W5H5_HUMAN
- Q8IXX3_HUMAN
Variants for HERC3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for HERC3 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs187220478 | Likely Benign: not provided | 88,697,328(+) |
C/T NM_153757.4(NAP1L5):c.427G>A (p.Glu143Lys) |
MISSENSE_VARIANT,INTRON | |
| rs1804080 | - |
p.Glu946Gln |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2850n106 | CNV | deletion | 24896259 |
| esv1953449 | CNV | deletion | 18987734 |
| esv2278581 | CNV | deletion | 18987734 |
| esv2640318 | CNV | deletion | 19546169 |
| esv2657218 | CNV | deletion | 23128226 |
| esv2727952 | CNV | deletion | 23290073 |
| esv2727953 | CNV | deletion | 23290073 |
| esv3564216 | CNV | deletion | 23714750 |
| esv5387 | CNV | loss | 18987735 |
| nsv1073354 | CNV | deletion | 25765185 |
| nsv291508 | CNV | deletion | 16902084 |
| nsv461575 | CNV | gain | 19166990 |
| nsv461576 | CNV | gain | 19166990 |
| nsv594805 | CNV | gain | 21841781 |
| nsv594806 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
6.67% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.28;
85.15% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HERC3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HERC3
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HERC3 Gene
Disorders for HERC3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epidural abscess |
|
|
Search HERC3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HERC3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for HERC3 Gene
Publications for HERC3 Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- HERC3 binding to and regulation by ubiquitin. (PMID: 11163799) Cruz C … Rosa JL (FEBS letters 2001) 3 4
- The human HERC3 gene maps to chromosome 4q21 by fluorescence in situ hybridization. (PMID: 10702688) Cruz C … Rosa JL (Cytogenetics and cell genetics 1999) 2 3
- Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PMID: 7584026) Nomura N … Tabata S (DNA research : an international journal for rapid publication of reports on genes and genomes 1994) 3 4
- The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. (PMID: 31586073) Capalbo L … D'Avino PP (Nature communications 2019) 3
ExternalLinks
Products for HERC3 Gene
- Custom Antibody ServicesOriGene Antibodies for HERC3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HERC3
- Search Origene for MassSpec and Protein Over-expression Lysates for HERC3
- Origene Custom Protein Services for HERC3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HERC3
- Browse OriGene Inhibitory RNA Products For HERC3
- OriGene qPCR primer pairs for HERC3
- OriGene qPCR primer pairs and template standards for HERC3
- OriGene CRISPR knockouts for HERC3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HERC3
- Sino Biological Human cDNA Clone for HERC3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for HERC3
- Novus Biologicals proteins and lysates for HERC3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for HERC3
- Abcam proteins for HERC3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for HERC3 (AFLGC-HERC3)
- VectorBuilder Custom and pre-made DNA vectors for HERC3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for HERC3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HERC3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HERC3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HERC3
- antibodies-online: Show 12 available HERC3 Antibodies ranked by validation data
- Compare Top HERC3 Antibodies
- Quality Products:
- antibodies-online: Search results for available HERC3 related products ranked by validation data
- antibodies-online: Search results for available HERC3 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for HERC3
- Search Santa Cruz Biotechnology (SCBT) for HERC3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HERC3
- Horizon Cell Lines for HERC3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HERC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HERC3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HERC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HERC3
- Boster Bio Antibodies for HERC3
- Browse Boster Bio ELISA Kits
Sources for HERC3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB