Aliases for HEPACAM2 Gene
External Ids for HEPACAM2 Gene
- HGNC: 27364
- Entrez Gene: 253012
- Ensembl: ENSG00000188175
- OMIM: 614133
- UniProtKB: A8MVW5
Previous GeneCards Identifiers for HEPACAM2 Gene
- GC07M092656
- GC07M092817
- GC07M087426
Summaries for HEPACAM2 Gene
-
This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients. [provided by RefSeq, Oct 2016]
GeneCards Summary for HEPACAM2 Gene
HEPACAM2 (HEPACAM Family Member 2) is a Protein Coding gene. Diseases associated with HEPACAM2 include Myelodysplastic Syndrome. An important paralog of this gene is HEPACAM.
UniProtKB/Swiss-Prot for HEPACAM2 Gene
-
Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.
Additional gene information for HEPACAM2 Gene
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HEPACAM2 Gene
Genomics for HEPACAM2 Gene
GeneHancer (GH) Regulatory Elements for HEPACAM2 Gene
Promoters and enhancers for HEPACAM2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH07J093231 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 650.7 | +0.2 | 152 | 2.1 | PKNOX1 SMAD1 FOXA2 ARNT ARID4B SIN3A ZNF2 YY1 POLR2B ZNF766 | VPS50 HEPACAM2 KRIT1 LOC105375403 PEX1 SAMD9L GATAD1 FAM133B BET1 | |
| GH07J093219 | Promoter | 1 | EPDnew | 650.4 | +12.8 | 12773 | 0.1 | LEF1 TEAD4 TAL1 TCF12 CTBP1 POLR2A SCRT2 SOX6 MTA2 NCOA1 | HEPACAM2 SAMD9L | |
| GH07J093165 | Enhancer | 0.8 | FANTOM5 ENCODE | 10.6 | +66.6 | 66626 | 1.2 | SRF CEBPB CEBPG ATF7 MEF2B DPF2 RELA | HEPACAM2 SAMD9 SAMD9L | |
| GH07J093558 | Enhancer | 0.6 | Ensembl | 9.6 | -327.2 | -327204 | 1.4 | ATF1 NR2F1 ATF2 ZNF335 JUND ZNF692 CREB1 ATF7 KLF13 | MIR489 MIR653 HEPACAM2 CALCR LOC105375400 | |
| GH07J093217 | Enhancer | 0.4 | FANTOM5 | 4.6 | +14.4 | 14357 | 0.2 | ZBTB2 NFRKB | HEPACAM2 SAMD9L |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around HEPACAM2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the HEPACAM2 gene promoter:
-
- Nkx2-5
- Sox5
- Pax-6
- Nkx3-1
- MEF-2A
- aMEF-2
Regulatory Element Products
Genomic Locations for HEPACAM2 Gene
Genomic Locations for HEPACAM2 Gene
- chr7:93,188,586-93,232,297
- (GRCh38/hg38)
- Size:
- 43,712 bases
- Orientation:
- Minus strand
- chr7:92,817,899-92,855,837
- (GRCh37/hg19)
- Size:
- 37,939 bases
- Orientation:
- Minus strand
Genomic View for HEPACAM2 Gene
Genes around HEPACAM2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q21.2 by Entrez Gene
- 7q21.2 by HGNC
- 7q21.2 by Ensembl
HEPACAM2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HEPACAM2 Gene
Proteins for HEPACAM2 Gene
-
Protein details for HEPACAM2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A8MVW5-HECA2_HUMAN
- Recommended name:
- HEPACAM family member 2
- Protein Accession:
- A8MVW5
- B3KTT4
- B4DPJ1
- B9EG93
- E9PDV5
- Q6UXI0
Protein attributes for HEPACAM2 Gene
- Size:
- 462 amino acids
- Molecular mass:
- 51407 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for HEPACAM2 Gene
- Poly-ADP-ribosylated (PARsylated) by tankyrase TNKS during late G2 and prophase, leading to translocation to mitotic centrosomes.
- N-glycosylated.
- Glycosylation at Asn320, isoforms=2, 3288, isoforms=2, 3216, isoforms=2, 3165, Asn129, and Asn85
- Modification sites at PhosphoSitePlus
Other Protein References for HEPACAM2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for HEPACAM2
-
Abcam antibodies for HEPACAM2
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-
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-
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-
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Assay Products
No data available for DME Specific Peptides for HEPACAM2 Gene
Domains & Families for HEPACAM2 Gene
Gene Families for HEPACAM2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for HEPACAM2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HEPACAM2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for HEPACAM2 Gene
Function for HEPACAM2 Gene
Molecular function for HEPACAM2 Gene
- UniProtKB/Swiss-Prot Function:
- Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.
Phenotypes From GWAS Catalog for HEPACAM2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 22864114 |
Phenotypes for HEPACAM2 Gene
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-
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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-
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Horizon Cell Lines for HEPACAM2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HEPACAM2 Gene
Localization for HEPACAM2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HEPACAM2 Gene
- Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=In interphase, localizes to the Golgi apparatus. Localizes to centrosomes and spindles during prophase, prometaphase, and metaphase of mitosis, and to midbodies at telophase. Translocation to mitotic centrosomes is the result of poly-ADP-ribosylation (PARsylation). {ECO:0000269 PubMed:19358830, ECO:0000269 PubMed:22864114}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| golgi apparatus | 5 |
| plasma membrane | 3 |
| extracellular | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005794 | Golgi apparatus | IDA,IEA | 22864114 |
| GO:0005813 | centrosome | IDA | 22864114 |
| GO:0005815 | microtubule organizing center | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for HEPACAM2 Gene
Pathways & Interactions for HEPACAM2 Gene
No Data Available
Interacting Proteins for HEPACAM2 Gene
GPS-Prot Interaction Network for HEPACAM2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007098 | centrosome cycle | IMP | 22864114 |
| GO:0051301 | cell division | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for HEPACAM2 Gene
Transcripts for HEPACAM2 Gene
mRNA/cDNA for HEPACAM2 Gene
- (6) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (47) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000440868 2060 bps (uc010lff.5)
- ENST00000341723 2122 bps (uc003uml.5)
- ENST00000394468 2148 bps (uc003umm.5)
- ENST00000453812 1869 bps (uc011khy.4)
- ENST00000492616 787 bps (uc064fjh.1)
Unigene Clusters for HEPACAM2 Gene
CRISPR Products
-
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for HEPACAM2
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miRNA Products
Inhibitory RNA Products
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Clone Products
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for HEPACAM2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HEPACAM2
- Applied Biological Materials Clones for HEPACAM2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: |
Expression for HEPACAM2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Ventral Pancreatic Bud
-
Testis (Reproductive System)
- Secondary Spermatocyte Seminiferous Tubules
-
Gonad
- Secondary Spermatocyte Seminiferous Tubules
- Spleen (Hematopoietic System)
- Blood (Cardiovascular System)
- Neural Tube (Nervous System)
mRNA differential expression in normal tissues according to GTEx for HEPACAM2 Gene
This gene is overexpressed in Colon - Transverse (x22.6), Small Intestine - Terminal Ileum (x9.0), Pituitary (x5.7), and Kidney - Cortex (x5.0).
NURSA nuclear receptor signaling pathways regulating expression of HEPACAM2 Gene:
HEPACAM2SOURCE GeneReport for Unigene cluster for HEPACAM2 Gene:
Hs.443169mRNA Expression by UniProt/SwissProt for HEPACAM2 Gene:
A8MVW5-HECA2_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for HEPACAM2 Gene
- Kidney(4.2)
Primer Products
-
OriGene qPCR primer pairs for HEPACAM2
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for HEPACAM2 Gene
Orthologs for HEPACAM2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | HEPACAM2 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | HEPACAM2 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | HEPACAM2 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Hepacam2 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Hepacam2 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | HEPACAM2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | HEPACAM2 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | HEPACAM2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | hepacam2 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC558612 33 |
|
||
| hepacam2 34 |
|
OneToOne |
- Species where no ortholog for HEPACAM2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for HEPACAM2 Gene
- ENSEMBL:
- Gene Tree for HEPACAM2 (if available)
- TreeFam:
- Gene Tree for HEPACAM2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HEPACAM2: view image
Paralogs for HEPACAM2 Gene
Variants for HEPACAM2 Gene
| SNP ID | Clin | Chr 07 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs193921119 | uncertain-significance, Malignant tumor of prostate | 93,219,492(-) | C/T | initiator_codon_variant, intron_variant, missense_variant | |
| VAR_042976 | A breast cancer sample | p.Gly31Arg | |||
| rs1000022155 | -- | 93,222,801(-) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000176690 | -- | 93,195,105(-) | AAAA/AAA | intron_variant | |
| rs1000206833 | -- | 93,197,128(-) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2581618 | CNV | deletion | 19546169 |
| nsv528267 | CNV | loss | 19592680 |
Residual Variation Intolerance Score:
52.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.93;
49.02% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HEPACAM2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HEPACAM2 Gene
Disorders for HEPACAM2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myelodysplastic syndrome |
|
|
Search HEPACAM2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HEPACAM2
No data available for UniProtKB/Swiss-Prot and Genatlas for HEPACAM2 Gene
Publications for HEPACAM2 Gene
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 2 3 4 58
- Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation. (PMID: 22864114) Ozaki Y … Inaba T (Molecular cell 2012) 3 4 58
- Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome. (PMID: 19358830) Asou H … Inaba T (Biochemical and biophysical research communications 2009) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- GeneTex HEPACAM2 Antibody for HEPACAM2
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- Overview of 120 available HEPACAM2 gene related products
- genomics-online: primer clones - Search results for 120 available HEPACAM2 gene related products
- Overview of 120 available HEPACAM2 gene related products
- genomics-online: shRNA clones - Search results for 120 available HEPACAM2 gene related products
- Overview of 120 available HEPACAM2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HEPACAM2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HEPACAM2
- GeneCopoeia miRNA 3'UTR Target clone products for HEPACAM2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HEPACAM2
- Boster Bio Antibodies for HEPACAM2
- Browse Boster Bio ELISA Kits
Sources for HEPACAM2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt