Aliases for HELQ Gene
External Ids for HELQ Gene
Previous GeneCards Identifiers for HELQ Gene
HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 [PubMed 11751861]).[supplied by OMIM, Mar 2008]
GeneCards Summary for HELQ Gene
HELQ (Helicase, POLQ Like) is a Protein Coding gene. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is POLQ.
UniProtKB/Swiss-Prot for HELQ Gene
Single-stranded DNA-dependent ATPase and 5 to 3 DNA helicase (PubMed:11751861). Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links (PubMed:19995904).