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HCG4B Gene(RNA Gene)

HLA Complex Group 4B

GCID:
GC06M030345
GIFtS:
15
Genes Participants
UDN Logo

Aliases for HCG4B Gene

Subcategory (RNA class) for HCG4B Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for HCG4B Gene

  • HLA Complex Group 4B 2 3
  • HLA Complex Group 4B (Non-Protein Coding) 2 3 5
  • HLA Complex Group 4 Pseudogene 6 2 3
  • HCGIV-6 Pseudogene 2 3
  • BPG309N1.1 3
  • BQB90C11.3 3
  • BCX67J3.3 3
  • HCGIV-06 3
  • HCGIV-6 3
  • HCGIV.5 3
  • HCG4P6 3

External Ids for HCG4B Gene

Previous HGNC Symbols for HCG4B Gene

  • HCG4P6

Previous GeneCards Identifiers for HCG4B Gene

  • GC06M029898
  • GC06M029906
  • GC06M029921
  • GC06M029934
  • GC06M029954
  • GC06M030015
  • GC06M029958
  • GC06M030024
  • GC06M030045
  • GC06M030117
  • GC06M030067
  • GC06M030209
  • GC06M030268
  • GC06M030302

Summaries for HCG4B Gene

GeneCards Summary for HCG4B Gene

HCG4B (HLA Complex Group 4B) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for HCG4B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HCG4B Gene

Genomics for HCG4B Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for HCG4B Gene

Promoters and enhancers for HCG4B Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH06J029924 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 650.7 +1.1 1142 3.6 MLX ARID4B DMAP1 RFX5 YY1 KLF11 RXRA SMAD5 CEBPB ZHX2 HLA-K GC06M030389 HCG4B HLA-A MICD ZFP57 HLA-J HLA-H HCG4P3 RPL23AP1
GH06J029928 Enhancer 0.4 Ensembl dbSUPER 650.7 -1.5 -1486 0.2 GC06M030389 HCG4B PIR44105 HLA-H HLA-A HCG4P3 HLA-K
GH06J030715 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 19 -792.3 -792311 7.7 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 MDC1 TUBB DDX39B LY6G5B TRIM39 DHX16 PPP1R10 ZNRD1 PAIP1P1 NRM
GH06J028977 Promoter/Enhancer 2 Ensembl ENCODE dbSUPER 19 +946.8 946840 6.5 MLX DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC MEF2D TRE-CTC1-6 TRF-GAA1-2 ZKSCAN3 ZKSCAN8 ZKSCAN4 TRIM27 ZSCAN12 HLA-K ZSCAN9 ZNF311
GH06J030746 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 19.1 -824.2 -824212 9.5 PKNOX1 FOXA2 ARID4B NEUROD1 SIN3A FEZF1 ZNF2 YY1 ZNF766 FOS RN7SL353P MDC1 IER3 TRIM39 DDX39B DHX16 LY6G5B NRM ZNRD1 GTF2H4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HCG4B on UCSC Golden Path with GeneCards custom track

Genomic Locations for HCG4B Gene

Genomic Locations for HCG4B Gene
chr6:29,924,592-29,927,215
(GRCh38/hg38)
Size:
2,624 bases
Orientation:
Minus strand
chr6:29,892,369-29,893,428
(GRCh37/hg19)
Size:
1,060 bases
Orientation:
Minus strand

Genomic View for HCG4B Gene

Genes around HCG4B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HCG4B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HCG4B Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for HCG4B Gene

Proteins for HCG4B Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for HCG4B Gene

No Post-translational modifications

No data available for DME Specific Peptides for HCG4B Gene

Domains & Families for HCG4B Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HCG4B Gene

Function for HCG4B Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for HCG4B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HCG4B Gene

Localization for HCG4B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HCG4B Gene

Pathways & Interactions for HCG4B Gene

SuperPathways for HCG4B Gene

PathCards logo More details on SuperPathways for HCG4B
No Data Available

Interacting Proteins for HCG4B Gene

Gene Ontology (GO) - Biological Process for HCG4B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HCG4B Gene

Drugs & Compounds for HCG4B Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for HCG4B Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for HCG4B Gene

(3) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(1) RNA Central transcripts :

Unigene Clusters for HCG4B Gene

HLA complex group 4B (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HCG4B Gene

No ASD Table

Relevant External Links for HCG4B Gene

GeneLoc Exon Structure for
HCG4B
ECgene alternative splicing isoforms for
HCG4B

Expression for HCG4B Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HCG4B Gene

mRNA expression in normal human tissues for HCG4B Gene
mRNA expression by BioGPS for HCG4B Gene

NURSA nuclear receptor signaling pathways regulating expression of HCG4B Gene:

HCG4B

SOURCE GeneReport for Unigene cluster for HCG4B Gene:

Hs.661198
genes like me logo Genes that share expression patterns with HCG4B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HCG4B Gene

Orthologs for HCG4B Gene

Evolution for HCG4B Gene

ENSEMBL:
Gene Tree for HCG4B (if available)
TreeFam:
Gene Tree for HCG4B (if available)

No data available for Orthologs for HCG4B Gene

Paralogs for HCG4B Gene

No data available for Paralogs for HCG4B Gene

Variants for HCG4B Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for HCG4B Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1001533776 -- 29,926,859(-) C/T non_coding_transcript_variant
rs1001593383 -- 29,927,085(-) G/C non_coding_transcript_variant
rs1002330075 -- 29,925,712(-) T/C non_coding_transcript_variant
rs1002589118 -- 29,924,730(-) T/C non_coding_transcript_variant
rs1004745616 -- 29,926,839(-) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for HCG4B Gene

Variant ID Type Subtype PubMed ID
nsv965704 CNV duplication 23825009
nsv823470 CNV loss 20364138
nsv823469 CNV loss 20364138
nsv820564 CNV deletion 20802225
nsv601450 CNV gain 21841781
nsv601443 CNV loss 21841781
nsv601394 CNV gain+loss 21841781
nsv601331 CNV loss 21841781
nsv601264 CNV loss 21841781
nsv5240 CNV deletion 18451855
nsv508398 CNV deletion 20534489
nsv499693 CNV loss 21111241
nsv462733 CNV loss 19166990
nsv442976 CNV loss 18776908
nsv437962 CNV loss 16468122
nsv1161354 CNV deletion 26073780
nsv1144137 CNV deletion 24896259
nsv1122126 CNV deletion 24896259
nsv10810 CNV gain+loss 18304495
nsv1074389 CNV deletion 25765185
nsv1029669 CNV loss 25217958
esv6014 CNV loss 19470904
esv3890806 CNV loss 25118596
esv3608493 CNV loss 21293372
esv3570849 CNV loss 25503493
esv3567498 CNV deletion 23714750
esv3567496 CNV deletion 23714750
esv3415023 CNV duplication 20981092
esv3369212 CNV duplication 20981092
esv3332677 CNV duplication 20981092
esv32544 CNV gain+loss 17666407
esv3124 CNV loss 18987735
esv2763941 CNV gain+loss 21179565
esv2761013 CNV loss 21179565
esv2759412 CNV gain+loss 17122850
esv2756714 CNV loss 18971310
esv2756697 CNV loss 18971310
esv2731775 CNV deletion 23290073
esv2674187 CNV deletion 23128226
esv2670487 CNV deletion 23128226
esv2665698 CNV deletion 23128226
esv2659548 CNV deletion 23128226
esv25966 CNV gain+loss 19812545
esv2589773 CNV loss 19546169
dgv993e201 CNV deletion 23290073
dgv992e201 CNV deletion 23290073
dgv7e195 CNV deletion 20811451
dgv5939n100 CNV loss 25217958
dgv57e213 CNV loss 24956385
dgv3467e59 CNV duplication 20981092
dgv221n111 CNV duplication 26073780
dgv220n111 CNV duplication 26073780
dgv212e55 CNV loss 17911159
dgv211e55 CNV loss 17911159
dgv1735e212 CNV loss 25503493
dgv1734e212 CNV loss 25503493
dgv1733e212 CNV loss 25503493
dgv1731e212 CNV loss 25503493
dgv1729e212 CNV gain 25503493
dgv1728e212 CNV gain 25503493
dgv116n17 CNV loss 16327808
dgv1089e199 CNV deletion 23128226
dgv1088e199 CNV deletion 23128226
dgv1087e199 CNV deletion 23128226
dgv1086e199 CNV deletion 23128226
dgv10362n54 CNV loss 21841781
dgv10361n54 CNV loss 21841781
dgv10360n54 CNV loss 21841781
dgv10359n54 CNV loss 21841781
dgv10353n54 CNV loss 21841781
dgv10352n54 CNV loss 21841781
dgv10348n54 CNV loss 21841781
dgv10347n54 CNV loss 21841781
dgv10346n54 CNV loss 21841781
dgv10344n54 CNV loss 21841781
dgv10342n54 CNV loss 21841781

Additional Variant Information for HCG4B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HCG4B

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HCG4B Gene

Disorders for HCG4B Gene

Additional Disease Information for HCG4B

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for HCG4B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HCG4B Gene

Publications for HCG4B Gene

  1. Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region. (PMID: 10557312) Shiina T … Inoko H (Proceedings of the National Academy of Sciences of the United States of America 1999) 2 3 58
  2. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. (PMID: 16702430) Shiina T … Bahram S (Genetics 2006) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for HCG4B Gene

Sources for HCG4B Gene

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