Free for academic non-profit institutions. Other users need a Commercial license

Aliases for HCG18 Gene

Subcategory (RNA class) for HCG18 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HCG18 Gene

  • HLA Complex Group 18 (Non-Protein Coding) 2 3 5
  • HLA Complex Group 18 2

External Ids for HCG18 Gene

Previous GeneCards Identifiers for HCG18 Gene

  • GC00U915705
  • GC06U900759
  • GC06M030259
  • GC06M030053

Summaries for HCG18 Gene

GeneCards Summary for HCG18 Gene

HCG18 (HLA Complex Group 18 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for HCG18 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HCG18 Gene

Genomics for HCG18 Gene

GeneHancer (GH) Regulatory Elements for HCG18 Gene

Promoters and enhancers for HCG18 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I030324 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 591.2 +0.7 728 3.5 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 HCG18 HCG17 TRIM39 RPL23AP1 MICD GABBR1 HLA-E GTF2H4 VARS2 ZNRD1ASP
GH06I030328 Promoter 0.6 EPDnew 550.8 -1.8 -1774 0.1 ZNF512 HCG18 TRIM39-RPP21 HLA-U TRIM39 PIR50234
GH06I030162 Promoter/Enhancer 1.5 EPDnew ENCODE 107.1 +163.4 163390 2.8 ZFP64 ARID4B DMAP1 YY1 SLC30A9 ZNF213 ZNF302 SP3 SP5 ZC3H11A TRIM10 TRIM15 MDC1 GTF2H4 HCG18 ZNRD1ASP PPP1R10 TRIM39 ETF1P1 PAIP1P1
GH06I030907 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 73.1 -581.3 -581301 2.2 CLOCK DMAP1 YBX1 IRF4 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF548 GTF2H4 VARS2 GC06P031581 MDC1 DDX39B LY6G5B TRIM39 LSM2 PPP1R10 HCG18
GH06I030715 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 37.1 -392.4 -392370 7.7 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 MDC1 TUBB DDX39B TRIM39 DHX16 LY6G5B PPP1R10 ZNRD1 PAIP1P1 NRM
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around HCG18 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the HCG18 gene promoter:

Genomic Locations for HCG18 Gene

Genomic Locations for HCG18 Gene
chr6:30,287,397-30,327,156
(GRCh38/hg38)
Size:
39,760 bases
Orientation:
Minus strand
chr6:30,255,174-30,294,927
(GRCh37/hg19)

Genomic View for HCG18 Gene

Genes around HCG18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HCG18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HCG18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HCG18 Gene

Post-translational modifications for HCG18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HCG18 Gene

Domains & Families for HCG18 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HCG18 Gene

Function for HCG18 Gene

Phenotypes From GWAS Catalog for HCG18 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HCG18 Gene

Localization for HCG18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HCG18 Gene

Pathways & Interactions for HCG18 Gene

SuperPathways for HCG18 Gene

No Data Available

Interacting Proteins for HCG18 Gene

Gene Ontology (GO) - Biological Process for HCG18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HCG18 Gene

Drugs & Compounds for HCG18 Gene

No Compound Related Data Available

Transcripts for HCG18 Gene

mRNA/cDNA for HCG18 Gene

(9) Additional mRNA sequences :
(16) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HCG18 Gene

HLA complex group 18 (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for HCG18 Gene

No ASD Table

Relevant External Links for HCG18 Gene

GeneLoc Exon Structure for
HCG18
ECgene alternative splicing isoforms for
HCG18

Expression for HCG18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HCG18 Gene

NURSA nuclear receptor signaling pathways regulating expression of HCG18 Gene:

HCG18

SOURCE GeneReport for Unigene cluster for HCG18 Gene:

Hs.485041
genes like me logo Genes that share expression patterns with HCG18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HCG18 Gene

Orthologs for HCG18 Gene

Evolution for HCG18 Gene

ENSEMBL:
Gene Tree for HCG18 (if available)
TreeFam:
Gene Tree for HCG18 (if available)

No data available for Orthologs for HCG18 Gene

Paralogs for HCG18 Gene

No data available for Paralogs for HCG18 Gene

Variants for HCG18 Gene

Sequence variations from dbSNP and Humsavar for HCG18 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000078658 -- 30,298,192(-) T/C intron_variant
rs1000187876 -- 30,310,481(-) C/A intron_variant
rs1000247515 -- 30,327,440(-) A/G upstream_transcript_variant
rs1000317461 -- 30,299,731(-) T/C intron_variant
rs1000348443 -- 30,299,524(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for HCG18 Gene

Variant ID Type Subtype PubMed ID
esv3411275 CNV duplication 20981092
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1144137 CNV deletion 24896259
nsv601264 CNV loss 21841781

Additional Variant Information for HCG18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HCG18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HCG18 Gene

Disorders for HCG18 Gene

Additional Disease Information for HCG18

No disorders were found for HCG18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HCG18 Gene

Publications for HCG18 Gene

  1. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. (PMID: 20622878) Remmers EF … Gül A (Nature genetics 2010) 44 58
  2. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PMID: 19010793) Baranzini SE … Oksenberg JR (Human molecular genetics 2009) 44 58
  3. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. (PMID: 18204098) Hom G … Behrens TW (The New England journal of medicine 2008) 44 58
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for HCG18 Gene

Sources for HCG18 Gene

Content
Loading form....