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Aliases for HCG18 Gene

Subcategory (RNA class) for HCG18 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for HCG18 Gene

  • HLA Complex Group 18 2 3 5
  • HLA Complex Group 18 (Non-Protein Coding) 2 3

External Ids for HCG18 Gene

Previous GeneCards Identifiers for HCG18 Gene

  • GC00U915705
  • GC06U900759
  • GC06M030259
  • GC06M030053

Summaries for HCG18 Gene

GeneCards Summary for HCG18 Gene

HCG18 (HLA Complex Group 18) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for HCG18 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HCG18 Gene

Genomics for HCG18 Gene

GeneHancer (GH) Regulatory Elements for HCG18 Gene

Promoters and enhancers for HCG18 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J030324 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 653.9 +0.9 856 3.8 SP1 CC2D1A ELF3 ZFX MNT NKRF MLLT1 POLR2A GTF2F1 CSDE1 HCG18 HCG17 TRIM39 MDC1 GTF2H4 ZNRD1ASP RPL23AP1 ABCF1 PAIP1P1 DHX16
GH06J030328 Promoter 0.6 EPDnew 600.7 -1.9 -1868 0.1 ZNF512 HCG18 TRIM39 TRIM39-RPP21 PIR50234
GH06J030162 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 106.9 +163.4 163371 2.8 ELF3 MNT POLR2A ZNF121 CEBPG AHR SP7 SP1 PPARG SP5 TRIM10 TRIM15 MDC1 GTF2H4 HCG18 ZNRD1ASP PPP1R10 TRIM39 ETF1P1 PAIP1P1
GH06J030715 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 67.9 -392.4 -392370 7.7 HDGF ZNF652 SP1 ZFX CC2D1A ELF3 CTCF ZKSCAN8 MNT SIX5 MDC1 TUBB LY6G5B DDX39B TRIM39 DHX16 HCG18 PPP1R10 GTF2H4 PAIP1P1
GH06J030907 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 73.1 -581.3 -581301 2.2 SP1 CC2D1A ELF3 ZKSCAN8 MNT SIX5 ZNF148 NKRF POLR2A MLLT1 GTF2H4 VARS2 GC06P032828 MDC1 DDX39B LY6G5B LSM2 TRIM39 PPP1R10 DHX16
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HCG18 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the HCG18 gene promoter:
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • Nkx2-5
  • p53
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for HCG18 Gene

Genomic Locations for HCG18 Gene
39,760 bases
Minus strand
39,754 bases
Minus strand

Genomic View for HCG18 Gene

Genes around HCG18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HCG18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HCG18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HCG18 Gene

No data available for DME Specific Peptides for HCG18 Gene

Domains & Families for HCG18 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HCG18 Gene

Function for HCG18 Gene

Phenotypes From GWAS Catalog for HCG18 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HCG18 Gene

Localization for HCG18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HCG18 Gene

Pathways & Interactions for HCG18 Gene

PathCards logo

SuperPathways for HCG18 Gene

No Data Available

Interacting Proteins for HCG18 Gene

Gene Ontology (GO) - Biological Process for HCG18 Gene


No data available for Pathways by source and SIGNOR curated interactions for HCG18 Gene

Drugs & Compounds for HCG18 Gene

No Compound Related Data Available

Transcripts for HCG18 Gene

mRNA/cDNA for HCG18 Gene

(7) Additional mRNA sequences :
(16) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(20) RNA Central transcripts :

Unigene Clusters for HCG18 Gene

HLA complex group 18 (non-protein coding):
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for HCG18 Gene

No ASD Table

Relevant External Links for HCG18 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for HCG18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HCG18 Gene

NURSA nuclear receptor signaling pathways regulating expression of HCG18 Gene:


SOURCE GeneReport for Unigene cluster for HCG18 Gene:

genes like me logo Genes that share expression patterns with HCG18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HCG18 Gene

Orthologs for HCG18 Gene

Evolution for HCG18 Gene

Gene Tree for HCG18 (if available)
Gene Tree for HCG18 (if available)

No data available for Orthologs for HCG18 Gene

Paralogs for HCG18 Gene

No data available for Paralogs for HCG18 Gene

Variants for HCG18 Gene

Sequence variations from dbSNP and Humsavar for HCG18 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000078658 -- 30,298,192(-) T/C intron_variant
rs1000187876 -- 30,310,481(-) C/A intron_variant
rs1000247515 -- 30,327,440(-) A/G upstream_transcript_variant
rs1000317461 -- 30,299,731(-) T/C intron_variant
rs1000348443 -- 30,299,524(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for HCG18 Gene

Variant ID Type Subtype PubMed ID
esv3411275 CNV duplication 20981092
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1144137 CNV deletion 24896259
nsv601264 CNV loss 21841781

Additional Variant Information for HCG18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HCG18 Gene

Disorders for HCG18 Gene

Additional Disease Information for HCG18

No disorders were found for HCG18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for HCG18 Gene

Publications for HCG18 Gene

  1. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. (PMID: 20622878) Remmers EF … Gül A (Nature genetics 2010) 45 58
  2. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PMID: 19010793) Baranzini SE … Oksenberg JR (Human molecular genetics 2009) 45 58
  3. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. (PMID: 18204098) Hom G … Behrens TW (The New England journal of medicine 2008) 45 58
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for HCG18 Gene

Sources for HCG18 Gene

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