Aliases for HCFC2 Gene
External Ids for HCFC2 Gene
Previous GeneCards Identifiers for HCFC2 Gene
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for HCFC2 Gene
HCFC2 (Host Cell Factor C2) is a Protein Coding gene. Diseases associated with HCFC2 include Herpes Simplex. Among its related pathways are Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity. An important paralog of this gene is HCFC1.