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Aliases for HCAR2 Gene
Aliases for HCAR2 Gene
External Ids for HCAR2 Gene
- HGNC: 24827
- NCBI Entrez Gene: 338442
- Ensembl: ENSG00000182782
- OMIM®: 609163
- UniProtKB/Swiss-Prot: Q8TDS4
Previous HGNC Symbols for HCAR2 Gene
- GPR109A
Previous GeneCards Identifiers for HCAR2 Gene
- GC12M123187
Summaries for HCAR2 Gene
GeneCards Summary for HCAR2 Gene
HCAR2 (Hydroxycarboxylic Acid Receptor 2) is a Protein Coding gene. Diseases associated with HCAR2 include Pellagra and Diversion Colitis. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and nicotinic acid receptor activity. An important paralog of this gene is HCAR3.
UniProtKB/Swiss-Prot Summary for HCAR2 Gene
-
Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
Additional gene information for HCAR2 Gene
- HGNC (24827)
- NCBI Entrez Gene (338442)
- Ensembl (ENSG00000182782)
- OMIM® (609163)
- UniProtKB/Swiss-Prot (Q8TDS4)
- Open Targets Platform(ENSG00000182782)
- Search for HCAR2 at DataMed
- Search for HCAR2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for HCAR2 Gene
Genomics for HCAR2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for HCAR2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around HCAR2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for HCAR2
Genomic Locations for HCAR2 Gene
Latest Assembly
- chr12:122,701,293-122,703,357
- (GRCh38/hg38)
- Size:
- 2,065 bases
- Orientation:
- Minus strand
Previous Assembly
- chr12:123,185,840-123,187,904
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 2,065 bases
- Orientation:
- Minus strand
- chr12:123,185,840-123,187,890
- (GRCh37/hg19 by Ensembl)
- Size:
- 2,051 bases
- Orientation:
- Minus strand
Genomic View for HCAR2 Gene
Genes around HCAR2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.31 by Entrez Gene
- 12q24.31 by Ensembl
HCAR2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for HCAR2 Gene
Proteins for HCAR2 Gene
-
Protein details for HCAR2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TDS4-HCAR2_HUMAN
- Recommended name:
- Hydroxycarboxylic acid receptor 2
- Protein Accession:
- Q8TDS4
- A0PJL5
- A7LGG3
Protein attributes for HCAR2 Gene
- Size:
- 363 amino acids
- Molecular mass:
- 41850 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for HCAR2 Gene
Other Protein References for HCAR2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for HCAR2
- Novus Biologicals Antibodies for HCAR2
-
Abcam antibodies for HCAR2
- Invitrogen Antibodies for HCAR2 (AFLGC-HCAR2)
-
Biorbyt antibodies for HCAR2
-
Boster Bio Antibodies for HCAR2
-
Custom Antibody ServicesProSci Antibodies for HCAR2
-
Santa Cruz Biotechnology (SCBT) Antibodies for HCAR2
Protein products for research
-
OriGene Purified Proteins for HCAR2
- Search Origene for MassSpec and Protein Over-expression Lysates for HCAR2
- Origene Custom Protein Services for HCAR2
Assay products for research
- antibodies-online: Show 4 available HCAR2 Elisa Kits ranked by validation data
- Compare Top HCAR2 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for HCAR2 Gene
Domains & Families for HCAR2 Gene
Gene Families for HCAR2 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- FDA approved drug targets
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for HCAR2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for HCAR2 Gene
- GenScript: Design optimal peptide antigens:
-
- Nicotinic acid receptor (HCAR2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8TDS4- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for HCAR2 Gene
Molecular function for HCAR2 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
Phenotypes From GWAS Catalog for HCAR2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0070553 | nicotinic acid receptor activity | ISS | -- |
Phenotypes for HCAR2 Gene
- MGI mutant phenotypes for HCAR2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for HCAR2:
Animal Models for HCAR2 Gene
- MGI Knock Outs for HCAR2:
-
- Hcar2 Hcar2<tm1Soff>
Animal Models for research
-
Taconic Biosciences Mouse Models for HCAR2
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for HCAR2 - Starting at $85 >
- * HCAR2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for HCAR2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HCAR2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HCAR2
miRNA for HCAR2 Gene
- miRTarBase miRNAs that target HCAR2
-
- hsa-miR-4446-5p (MIRT657477)
- hsa-miR-5006-3p (MIRT657478)
- hsa-miR-623 (MIRT657479)
- hsa-miR-4755-5p (MIRT657480)
- hsa-miR-2467-3p (MIRT657481)
- hsa-miR-6832-3p (MIRT657482)
- hsa-miR-5582-5p (MIRT657483)
- hsa-miR-33a-3p (MIRT657484)
- hsa-miR-409-3p (MIRT657485)
- hsa-miR-204-5p (MIRT657486)
- hsa-miR-211-5p (MIRT657487)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HCAR2
- Browse OriGene Inhibitory RNA Products For HCAR2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HCAR2
Clone products for research
- Applied Biological Materials (abm): Clones for HCAR2 - Starting at $45 >
- * HCAR2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for HCAR2
- Addgene plasmids for HCAR2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HCAR2
Cell Lines for research
-
Horizon Cell Lines for HCAR2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for HCAR2 Gene
Localization for HCAR2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for HCAR2 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cell Junctions (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0030054 | cell junction | IDA | -- |
Pathways & Interactions for HCAR2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
| 2 | Signaling by GPCR | ||
| 3 | cAMP signaling pathway | ||
| 4 | Hydroxycarboxylic acid-binding receptors | ||
Pathways by source for HCAR2 Gene
7 Reactome pathways for HCAR2 Gene
1 KEGG pathway for HCAR2 Gene
Interacting Proteins for HCAR2 Gene
GPS-Prot Interaction Network for HCAR2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001781 | neutrophil apoptotic process | IDA | 17932499 |
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | TAS | -- |
| GO:0033031 | positive regulation of neutrophil apoptotic process | IDA | 17932499 |
No data available for SIGNOR curated interactions for HCAR2 Gene
Drugs & Compounds for HCAR2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Niacin | Approved, Investigational | Nutra | Agonist, Full agonist, Target | 471,471 | ||
| Acipimox | Approved, Investigational | Pharma | Agonist, Full agonist | 23 | ||
| Clotrimazole | Approved, Vet_approved | Pharma | Target, partial agonist | 3138 | ||
| Inositol nicotinate | Approved, Withdrawn | Pharma | Target, agonist | 0 | ||
| Mepenzolate | Approved | Pharma | antagonist | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
(5) Tocris Compounds for HCAR2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 3,5-DHBA | Selective HCA1 agonist | 99-10-5 |
| Acifran | Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors | 72420-38-3 |
| IBC 293 | Selective agonist for the GPR109B (HM74) receptor. Antilipolytic | 306935-41-1 |
| LUF 6283 | HCA2 (GPR109A) partial agonist | 92933-48-7 |
| MK 1903 | Potent and selective GPR109A (HCA2) agonist | 1268882-43-4 |
(7) ApexBio Compounds for HCAR2 Gene
Transcripts for HCAR2 Gene
mRNA/cDNA for HCAR2 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000328880 2065 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for HCAR2 - Starting at $85 >
- * HCAR2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for HCAR2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HCAR2
-
Santa Cruz Biotechnology (SCBT) CRISPR for HCAR2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HCAR2
- Browse OriGene Inhibitory RNA Products For HCAR2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HCAR2
Clone products for research
- Applied Biological Materials (abm): Clones for HCAR2 - Starting at $45 >
- * HCAR2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for HCAR2
- Addgene plasmids for HCAR2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HCAR2
Relevant External Links for HCAR2 Gene
- GeneLoc Exon Structure for
- HCAR2
Expression for HCAR2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for HCAR2
SOURCE GeneReport for Unigene cluster for HCAR2 Gene:
Hs.524812mRNA Expression by UniProt/SwissProt for HCAR2 Gene:
Q8TDS4-HCAR2_HUMAN
Tissue specificity:
Expression largely restricted to adipose tissue and spleen. Expressed on mature neutrophils but not on immature neutrophils or eosinophils.
Evidence on tissue expression from TISSUES for HCAR2 Gene
- Pancreas(4.3)
- Blood(3.9)
- Spleen(3)
- Lung(2.8)
- Intestine(2.6)
- Skin(2.3)
- Liver(2.2)
- Lymph node(2.2)
- Nervous system(2.1)
- Bone marrow(2.1)
Primer products for research
-
OriGene qPCR primer pairs for HCAR2
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for HCAR2 Gene
Orthologs for HCAR2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GPR109A 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
| Rat (Rattus norvegicus) |
Mammalia | Niacr1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Niacr1 30 31 |
|
OneToMany | |
| Hcar2 17 |
|
||||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| Zebrafish (Danio rerio) |
Actinopterygii | hcar1-2 31 |
|
ManyToMany |
- Species where no ortholog for HCAR2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for HCAR2 Gene
- ENSEMBL:
- Gene Tree for HCAR2 (if available)
- TreeFam:
- Gene Tree for HCAR2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for HCAR2: view image
Paralogs for HCAR2 Gene
Paralogs for HCAR2 Gene
(14) SIMAP similar genes for HCAR2 Gene using alignment to 1 proteins:
- HCAR2_HUMAN
Variants for HCAR2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv308e214 | CNV | loss | 21293372 |
| esv26589 | CNV | gain | 19812545 |
| esv2746500 | CNV | deletion | 23290073 |
| esv3630980 | CNV | gain | 21293372 |
| esv8582 | CNV | loss | 19470904 |
| esv8843 | CNV | loss | 19470904 |
| nsv973132 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
56.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.42;
27.89% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for HCAR2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- HCAR2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for HCAR2 Gene
Disorders for HCAR2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| pellagra |
|
|
| diversion colitis |
|
|
Search HCAR2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for HCAR2
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for HCAR2 Gene
Publications for HCAR2 Gene
- Molecular identification of high and low affinity receptors for nicotinic acid. (PMID: 12522134) Wise A … Pike NB (The Journal of biological chemistry 2003) 2 3 4 26
- Molecular identification of nicotinic acid receptor. (PMID: 12646212) Soga T … Furuichi K (Biochemical and biophysical research communications 2003) 2 3 23 26
- International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B). (PMID: 21454438) Offermanns S … IJzerman AP (Pharmacological reviews 2011) 2 3 4
- Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A). (PMID: 17932499) Kostylina G … Simon HU (Cell death and differentiation 2008) 3 4 23
- Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A. (PMID: 16018973) Zhang Y … Cao G (Biochemical and biophysical research communications 2005) 3 23 26
ExternalLinks
Products for HCAR2 Gene
- View all 14 R&D Systems HCAR2 (HM74A/PUMA-G/GPR109A) Products
- View all 12 R&D Systems HCAR2 (HM74A/PUMA-G/GPR109A) Primary Antibodies
- View all R&D Systems HCAR2 (HM74A/PUMA-G/GPR109A) Small Molecules
- View all R&D Systems HCAR2 (HM74A/PUMA-G/GPR109A) cDNA Clones
- Learn more about R&D Systems custom HCAR2 antibody, protein, and immunoassay development services
- Custom Antibody ServicesOriGene Antibodies for HCAR2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for HCAR2
- Search Origene for MassSpec and Protein Over-expression Lysates for HCAR2
- Origene Custom Protein Services for HCAR2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for HCAR2
- Browse OriGene Inhibitory RNA Products For HCAR2
- OriGene qPCR primer pairs for HCAR2
- OriGene CRISPR knockouts for HCAR2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For HCAR2
- Sino Biological Human cDNA Clone for HCAR2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for HCAR2
- Novus Biologicals proteins and lysates for HCAR2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for HCAR2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for HCAR2
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for HCAR2 (AFLGC-HCAR2)
- ApexBio compounds for HCAR2
- VectorBuilder Custom and pre-made DNA vectors for HCAR2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for HCAR2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for HCAR2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for HCAR2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for HCAR2
- Addgene plasmids for HCAR2
- antibodies-online: Show 10 available HCAR2 Antibodies ranked by validation data
- Compare Top HCAR2 Antibodies
- antibodies-online: Show 4 available HCAR2 Elisa Kits ranked by validation data
- Compare Top HCAR2 Elisa Kits
- Quality Products:
- antibodies-online: Search results for available HCAR2 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for HCAR2
- Search Santa Cruz Biotechnology (SCBT) for HCAR2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for HCAR2
- Horizon Cell Lines for HCAR2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for HCAR2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for HCAR2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for HCAR2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for HCAR2
- Boster Bio Antibodies for HCAR2
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for HCAR2
Sources for HCAR2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
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- (166) Modomics
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- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB