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Aliases for HBB-HS-111 Gene

Aliases for HBB-HS-111 Gene

  • Beta-Globin Hypersensitive Site -111 3
  • HS-110 3
  • HS-111 3

External Ids for HBB-HS-111 Gene

Summaries for HBB-HS-111 Gene

Entrez Gene Summary for HBB-HS-111 Gene

  • This element represents a DNase I hypersensitive site located approximately 111 kb upstream of the HBE1 (hemoglobin, epsilon 1) gene in the beta-globin gene cluster. Chromosome conformation capture assays show that the orthologous mouse hypersensitive site is an integral part of the beta-globin active chromatin hub in erythroid cells, where it undergoes looping interactions with 3'HS1, which is located downstream of the beta-globin gene cluster, and this folding further enables interactions between the beta-globin locus control region (LCR) and active beta-globin gene promoters. [provided by RefSeq, Nov 2015]

GeneCards Summary for HBB-HS-111 Gene

HBB-HS-111 (Beta-Globin Hypersensitive Site -111) is a Biological Region gene.

Additional gene information for HBB-HS-111 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HBB-HS-111 Gene

Genomics for HBB-HS-111 Gene

Genomic Locations for HBB-HS-111 Gene

Genomic Locations for HBB-HS-111 Gene
chr11:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for HBB-HS-111 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for HBB-HS-111 Gene

No data available for GeneHancer (GH) Regulatory Elements for HBB-HS-111 Gene

Proteins for HBB-HS-111 Gene

Post-translational modifications for HBB-HS-111 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HBB-HS-111 Gene

Domains & Families for HBB-HS-111 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HBB-HS-111 Gene

Function for HBB-HS-111 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HBB-HS-111 Gene

Localization for HBB-HS-111 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HBB-HS-111 Gene

Pathways & Interactions for HBB-HS-111 Gene

PathCards logo

SuperPathways for HBB-HS-111 Gene

No Data Available

Interacting Proteins for HBB-HS-111 Gene

Gene Ontology (GO) - Biological Process for HBB-HS-111 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HBB-HS-111 Gene

Drugs & Compounds for HBB-HS-111 Gene

No Compound Related Data Available

Transcripts for HBB-HS-111 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for HBB-HS-111 Gene

No ASD Table

No data available for mRNA/cDNA for HBB-HS-111 Gene

Expression for HBB-HS-111 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HBB-HS-111 Gene

Orthologs for HBB-HS-111 Gene

No data available for Orthologs and Evolution for HBB-HS-111 Gene

Paralogs for HBB-HS-111 Gene

No data available for Paralogs for HBB-HS-111 Gene

Variants for HBB-HS-111 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for HBB-HS-111 Gene

Disorders for HBB-HS-111 Gene

No disorders were found for HBB-HS-111 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for HBB-HS-111 Gene

Publications for HBB-HS-111 Gene

  1. Epigenetic interplay at the β-globin locus. (PMID: 28161275) Lee WS … Vadolas J (Biochimica et biophysica acta. Gene regulatory mechanisms 2017) 3 58
  2. CTCF: the protein, the binding partners, the binding sites and their chromatin loops. (PMID: 23650640) Holwerda SJ … de Laat W (Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2013) 3 58
  3. β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications. (PMID: 24297746) Bian Q … Belmont AS (The Journal of cell biology 2013) 3 58
  4. Chromatin loop formation in the β-globin locus and its role in globin gene transcription. (PMID: 22610406) Kim A … Dean A (Molecules and cells 2012) 3 58
  5. Cohesin mediates chromatin interactions that regulate mammalian β-globin expression. (PMID: 21454523) Chien R … Yokomori K (The Journal of biological chemistry 2011) 3 58

No data available for External Links for HBB-HS-111 Gene

Products for HBB-HS-111 Gene

Sources for HBB-HS-111 Gene

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