Aliases for HAUS3 Gene
External Ids for HAUS3 Gene
Previous HGNC Symbols for HAUS3 Gene
Previous GeneCards Identifiers for HAUS3 Gene
This gene encodes a component of the HAUS augmin-like protein complex, which plays a key role in cytokinesis and mitosis. Disruption of the encoded protein causes mitotic defects resulting from fragmentation of centrosomes and microtubule destabilization. This gene shares its 5' exons with some transcripts from overlapping GeneID: 353497, which encodes a DNA polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
GeneCards Summary for HAUS3 Gene
HAUS3 (HAUS Augmin Like Complex Subunit 3) is a Protein Coding gene. Diseases associated with HAUS3 include Baritosis and Micronodular Basal Cell Carcinoma. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic.
UniProtKB/Swiss-Prot Summary for HAUS3 Gene
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.