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Aliases for HAS2-AS1 Gene

Subcategory (RNA class) for HAS2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for HAS2-AS1 Gene

  • HAS2 Antisense RNA 1 2 3 5
  • HAS2 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Hyaluronan Synthase 2 Antisense 2 3
  • HAS2 Antisense RNA (Non-Protein Coding) 2
  • Non-Protein Coding RNA 77 2
  • NCRNA00077 3
  • HAS2-AS 3
  • HAS2AS 3
  • HASNT 3

External Ids for HAS2-AS1 Gene

Previous HGNC Symbols for HAS2-AS1 Gene

  • HAS2AS
  • HAS2-AS

Previous GeneCards Identifiers for HAS2-AS1 Gene

  • GC08P122651

Summaries for HAS2-AS1 Gene

GeneCards Summary for HAS2-AS1 Gene

HAS2-AS1 (HAS2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with HAS2-AS1 include Oral Squamous Cell Carcinoma.

Additional gene information for HAS2-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HAS2-AS1 Gene

Genomics for HAS2-AS1 Gene

GeneHancer (GH) Regulatory Elements for HAS2-AS1 Gene

Promoters and enhancers for HAS2-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J121637 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 600.7 +0.9 859 7.5 CTCF ZNF148 SP7 PRDM1 RAD21 CREB1 CEBPG GLIS2 POLR2A ZBTB8A HAS2 HAS2-AS1 LINC02855 GC08M121582
GH08J121818 Enhancer 0.8 Ensembl ENCODE 11.5 +181.4 181433 6.2 RELA CREB1 SP1 ATF7 PKNOX1 JUNB NR2F2 BATF ATF2 NANOG HAS2 HAS2-AS1 PIR59127 GC08P121847
GH08J120932 Enhancer 0.9 Ensembl ENCODE 6.9 -706.0 -705957 2.2 ELF3 CEBPG PPARG ZNF644 ZNF7 RXRB RCOR2 ZNF341 GABPA IRF2 MRPL13 MTBP SNTB1 HAS2-AS1 ENSG00000253619 GC08P120906 LOC100133147
GH08J121784 Enhancer 0.5 Ensembl ENCODE 11 +145.4 145407 0.6 NR2F2 HAS2 HAS2-AS1 PIR59127 GC08M121742
GH08J121610 Enhancer 0.4 dbSUPER 11.4 -28.5 -28458 1.4 ZFHX2 EGR2 HAS2-AS1 HAS2 GC08M121582 GC08M121457
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around HAS2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for HAS2-AS1 Gene

Genomic Locations for HAS2-AS1 Gene
chr8:121,639,293-121,993,876
(GRCh38/hg38)
Size:
354,584 bases
Orientation:
Plus strand
chr8:122,651,533-122,657,565
(GRCh37/hg19)
Size:
6,033 bases
Orientation:
Plus strand

Genomic View for HAS2-AS1 Gene

Genes around HAS2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HAS2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HAS2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HAS2-AS1 Gene

Proteins for HAS2-AS1 Gene

Post-translational modifications for HAS2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for HAS2-AS1 Gene

Domains & Families for HAS2-AS1 Gene

Gene Families for HAS2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with HAS2-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HAS2-AS1 Gene

Function for HAS2-AS1 Gene

Phenotypes From GWAS Catalog for HAS2-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HAS2-AS1 Gene

Localization for HAS2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for HAS2-AS1 Gene

Pathways & Interactions for HAS2-AS1 Gene

PathCards logo

SuperPathways for HAS2-AS1 Gene

No Data Available

Interacting Proteins for HAS2-AS1 Gene

Gene Ontology (GO) - Biological Process for HAS2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HAS2-AS1 Gene

Drugs & Compounds for HAS2-AS1 Gene

No Compound Related Data Available

Transcripts for HAS2-AS1 Gene

mRNA/cDNA for HAS2-AS1 Gene

(3) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(9) RNA Central transcripts :

Unigene Clusters for HAS2-AS1 Gene

HAS2 antisense RNA 1:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for HAS2-AS1 Gene

No ASD Table

Relevant External Links for HAS2-AS1 Gene

GeneLoc Exon Structure for
HAS2-AS1
ECgene alternative splicing isoforms for
HAS2-AS1

Expression for HAS2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for HAS2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for HAS2-AS1 Gene

This gene is overexpressed in Testis (x9.2).

SOURCE GeneReport for Unigene cluster for HAS2-AS1 Gene:

Hs.668686
genes like me logo Genes that share expression patterns with HAS2-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for HAS2-AS1 Gene

Orthologs for HAS2-AS1 Gene

Evolution for HAS2-AS1 Gene

ENSEMBL:
Gene Tree for HAS2-AS1 (if available)
TreeFam:
Gene Tree for HAS2-AS1 (if available)

No data available for Orthologs for HAS2-AS1 Gene

Paralogs for HAS2-AS1 Gene

No data available for Paralogs for HAS2-AS1 Gene

Variants for HAS2-AS1 Gene

Sequence variations from dbSNP and Humsavar for HAS2-AS1 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1001127655 -- 121,641,253(+) A/G non_coding_transcript_variant
rs1002066268 -- 121,643,110(+) C/G intron_variant
rs1002128744 -- 121,642,644(+) T/G non_coding_transcript_variant
rs1002730767 -- 121,639,976(+) G/C non_coding_transcript_variant
rs1002773795 -- 121,641,908(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for HAS2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv1077067 CNV deletion 25765185
nsv831446 CNV loss 17160897

Additional Variant Information for HAS2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
HAS2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for HAS2-AS1 Gene

Disorders for HAS2-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for HAS2-AS1 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
oral squamous cell carcinoma
  • mouth squamous cell carcinoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for HAS2-AS1

genes like me logo Genes that share disorders with HAS2-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HAS2-AS1 Gene

Publications for HAS2-AS1 Gene

  1. Long noncoding RNA HAS2-AS1 mediates hypoxia-induced invasiveness of oral squamous cell carcinoma. (PMID: 28485478) Zhu G … Li L (Molecular carcinogenesis 2017) 2 3 58
  2. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. (PMID: 21357421) Michael DR … Bowen T (The Journal of biological chemistry 2011) 2 3 58
  3. HAS2-AS1 is a novel LH/hCG target gene regulating HAS2 expression and enhancing cumulus cells migration. (PMID: 30819231) Yung Y … Maman E (Journal of ovarian research 2019) 3 58
  4. Makin' sense of the antisense: HA expression and synthesis requires HAS2-AS1 and O-GlcNAcylation. (PMID: 25645084) Neill T … Zoeller J (Matrix biology : journal of the International Society for Matrix Biology 2015) 3 58
  5. Natural antisense transcript for hyaluronan synthase 2 (HAS2-AS1) induces transcription of HAS2 via protein O-GlcNAcylation. (PMID: 25183006) Vigetti D … Passi A (The Journal of biological chemistry 2014) 3 58

Products for HAS2-AS1 Gene

Sources for HAS2-AS1 Gene

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